Skip to main content
Log in

Nekrotisierende Fasziitis – eine klinische Diagnose

Necrotizing fasciitis – a clinical diagnosis

  • Kasuistiken
  • Published:
Der Orthopäde Aims and scope Submit manuscript

Zusammenfassung

Die nekrotisierende Fasziitis ist ein lebensbedrohliches Krankheitsbild, welches bei verzögerter Diagnostik und inadäquater Therapie zu Multiorganversagen und Tod führt. Wir berichten im Folgenden von einem 68-jährigen Patienten mit nekrotisierender Fasziitis des rechten Ellenbogens nach Bagatelltrauma und fulminantem septischem Verlauf mit Multiorganversagen und Langzeitbeatmung, dessen Leben und Extremität durch rechtzeitige Erstoperation und radikales Debridement erhalten werden konnte. Anhand dieses Fallberichtes werden die Besonderheiten der nekrotisierenden Fasziitis erläutert und ein Überblick über die aktuelle wissenschaftliche Literatur präsentiert.

Abstract

Necrotizing fasciitis is a life-threatening clinical pattern, which may lead to multi-organ failure and death with delayed diagnosis or inadequate treatment. We report on a 68-year old patient who developed necrotizing fasciitis of the right elbow with multiorgan failure and long-term ventilation after an accidental and minor injury. The patient survived as a result of an early diagnosis and surgical intervention. In this case report we want to clarify the diagnosis and treatment of necrotizing fasciitis and give an overview of the recent literature on the topic.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Abb. 1
Abb. 2
Abb. 3
Abb. 4
Abb. 5
Abb. 6

Literatur

  1. Anaya DA, Dellinger EP (2007) Necrotizing soft-tissue infection: diagnosis and management. Clin Infect Dis 44(5):705–710

    Article  CAS  PubMed  Google Scholar 

  2. Anaya DA, McMahon K, Nathens AB, Sullivan SR, Foy H, Bulger E (2005) Predictors of mortality and limb loss in necrotizing soft tissue infections. Arch Surg 140(2):151–157 (discussion 8)

    Article  PubMed  Google Scholar 

  3. Baer W et al (2002) Diagnosis and therapy of necrotizing fasciitis. Orthopade 31:551–555

    Article  CAS  PubMed  Google Scholar 

  4. Baharestani M (2008) Negative pressure wound therapy in the adjunctive management of necrotizing fasciitis: examining clinical outcomes. Ostomy Wound Manage 54(4):44–50

    PubMed  Google Scholar 

  5. Bisno AL, Stevens DL (1996) Streptococcal infections of the skin and the soft tissues. N Engl J Med 334:240–245

    Article  CAS  PubMed  Google Scholar 

  6. Carter PS, Banwell PE (2004) Necrotising fasciitis: a new management algorithm based on clinical classification. Int Wound J 1(3):189–198

    Article  PubMed  Google Scholar 

  7. Chao WN, Tsai SJ, Tsai CF, Su CH, Chan KS, Lee YT, Ueng KC, Lin DB, Chen CC, Chen SC (2012) The laboratory risk indicator for necrotizing fasciitis score for discernment of necrotizing fasciitis originated from vibrio vulnificus infections. J Trauma Acute Care Surg 73(6):1576–1582

    Article  PubMed  Google Scholar 

  8. Heitmann C, Pelzer M, Bickert B, Menke H, Germann G (2001) Chirurgisches Konzept und Ergebnisse bei nekrotisierender Fasciitis. Chirurg 72(2):168–173

    Article  CAS  PubMed  Google Scholar 

  9. Childers BJ, Potyondy LD, Nachreiner R, Rogers FR, Childers ER, Oberg KC et al (2002) Necrotizing fasciitis: a fourteen-year retrospective study of 163 consecutive patients. Am Surg 68(2):109–116

    PubMed  Google Scholar 

  10. Elliot D et al (2000) The microbiology of necrotizing soft tissue infections. Am J Surg 179:361–366

    Article  Google Scholar 

  11. Fontes RA Jr., Ogilvie CM, Miclau T (2000) Necrotizing soft-tissue infections. J Am Acad Orthop Surg 8(3):151–158

    Article  PubMed  Google Scholar 

  12. Glass GE, Sheil F, Ruston JC, Butler PE (2015) Necrotising soft tissue infection in a UK metropolitan population. Ann R Coll Surg Engl 97(1):46–51

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  13. Goh T, Goh LG, Ang CH, Wong CH (2014) Early diagnosis of necrotizing fasciitis. Br J Surg 101(1):e119–e125

    Article  CAS  PubMed  Google Scholar 

  14. Hackett SP, Stevens DL, Dahlstrom JJ, Long WB 3rd (2008) Modern concepts of the diagnosis and treatment of purpura fulminans. J Environ Pathol Toxicol Oncol 27(3):191–196

    Article  Google Scholar 

  15. Hahn H et al (2009) Medizinische Mikrobiologie und Infektiologie. Springer, Heildelberg

    Book  Google Scholar 

  16. Herr M, Grabein B et al (2011) Nekrotisierende Fasziitis Update 2011. Unfallchirurg 3:197

    Article  Google Scholar 

  17. Horas U, Herbst U, Hamann A, Ernst S (2008) Nekrotisierende Fasziitis durch Gruppe-G-Streptokokken. Orthopädie 37:592–594

    Article  CAS  Google Scholar 

  18. Ryssel H, Germann G, Riedel K, Kölensperger E (2007) Chirugisches Konzept und Ergebnisse bei nekrotisierender Fasziitis. Chirurg 78:1123–1129

    Article  CAS  PubMed  Google Scholar 

  19. Jones J (1870) Surgical memoirs of the War of the Rebellion: investigation upon the nature, casues, and treatment of hospital gangrene as prevailes on the Confederate Armes 1861–1865. Published for the United States Sanitary Commission by Hurd and Houghton, New York

    Google Scholar 

  20. Kayser et al (2005) Medizinische Mikrobiologie. Thieme, Stuttgart

    Google Scholar 

  21. Al Alayed K et al (2015) Red flags for necrotizing fasciitis: a case control study. Int J Infect Dis 36:15–20

    Article  PubMed  Google Scholar 

  22. Kujath P, Eckmann C (1996) Hyperbare Oxygenation als ergänzende Therapieform der nekrotisierenden Fasciitis. Dtsch Med Wochenschr 121:117

    Google Scholar 

  23. Kujath P, Eckmann C (1998) Die nekrotisierende Fasziitis und schwere Weichteilinfektionen durch Gruppe A‑Streptokokken-Diagnose, Therapie und Prognose. Dtsch Arztebl 95(8):A-408

    Google Scholar 

  24. Levenson RB, Singh AK, Novelline RA (2008) Fournier gangrene: role of imaging. Radiographics 28(2):519–528

    Article  PubMed  Google Scholar 

  25. McHenry CR, Piotrowski JJ, Petrinic D, Malangoni MA (1995) Determinants of mortality for necrotizing soft-tissue infections. Ann Surg 221(5):558–563 (discussion 63–65)

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  26. Naidoo SL, Campbell DL, Miller LM, Nicastro A (2005) Necrotizing fasciitis: areview. J Am Anim Hosp Assoc 41(2):104–109

    Article  PubMed  Google Scholar 

  27. Nordqvist G et al (2015) Ten years of treating necrotizing fasciitis. Infect Dis 47:319–325

    Article  Google Scholar 

  28. Kaul R, McGeer A, Low D, Green K (1997) Population based surveillaande for group a strptococal necrotizing fasciitis: clinical features. Prognostic indicators and microbiologic analysis of seventy cases. Am J Med 103(1):18–24. doi:10.1016/s0002-9343(97)00160-5

    Article  CAS  PubMed  Google Scholar 

  29. Roje Z, Matic D, Librenjak D, Dokuzovic S, Varvodic J (2011) Necrotizing fasciitis: literature review of contemporary strategies for diagnosing and management with three case reports: torso, abdominal wall, upper and lower limbs. World J Emerg Surg 6(1):46

    Article  PubMed  PubMed Central  Google Scholar 

  30. Rouse TM, Malangoni MA, Schulte WJ (1992) Necrotizing fasciitis – a preventable disaster. Surgery 92:765–770

    Google Scholar 

  31. Sarani B, Strong M, Pascual J, Schwab CW (2009) Necrotizing fasciitis: current concepts and review of the literature. J Am Coll Surg 208(2):279–288

    Article  PubMed  Google Scholar 

  32. Sarkar B et al (2010) Necrotizing soft tissue infections. Minerva Chir 65:347–362

    CAS  PubMed  Google Scholar 

  33. Schöneberg I (2008) In Deutschland selten auftretende Infektionskrankheiten - Ergebnisse aus der Meldepflicht. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 51(5):539–546. doi:10.1007/s00103-008-0521-x

    Article  PubMed  Google Scholar 

  34. Schulze M et al (2008) Necrotizing fasciitis: imaging findings. Rofo 180:587–590

    Article  CAS  PubMed  Google Scholar 

  35. Silberstein J et al (2008) Use of vacuum-assisted device for Fournier’s gangrene: a new paradigm. Rev Urol 10:76–80

    PubMed  PubMed Central  Google Scholar 

  36. Steinstrasser I, Sand M, Steinau HU (2009) Giant VAC in a patient with extensive necrotizing fasciitis. Int J Low Extrem Wounds 8(1):28–30

    Article  Google Scholar 

  37. Sudarsky LA, Laschinger GF, Coppa FC, Spencer C (1987) Improved results from a standardized approach in treating patients with necrotizing fasciitis. Ann Surg 206:661–665

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  38. Thomas AJ, Meyer TK (2012) Retrospective evaluation of laboratory-based diagnostic tools for cervical necrotizing fasciitis. Laryngoscope 122(12):2683–2687

    Article  PubMed  Google Scholar 

  39. Wall DB et al (2000) Objective criteria may assist in distinguishing necrotizing fasciitis from nonnecrotizin soft tissue infection. Am Surg 179:17–21

    Article  CAS  Google Scholar 

  40. Wilson B (1952) Necrotizing fasciitis. Am Surg 18(4):416–431

    CAS  PubMed  Google Scholar 

  41. Wong CH, Chang HC, Pasupathy S, Khin LW, Tan JL, Low CO (2003) Necrotizing fasciitis:clinical presentation, microbiology, and determinants of mortality. J Bone Joint Surg Am 85-A(8):1454–1460

    Article  PubMed  Google Scholar 

  42. Wong CH, Khin LW (2005) Clinical relevance of the LRINEC (Laboratory Risk Indicator for Necrotizing Fasciitis) Score for assessment of early necrotizing fasciitis. Crit Care Med 33(7):1677–1680

    Article  PubMed  Google Scholar 

  43. Wong CH et al (2008) Approach to debridement in necrotizing fasciitis. Am J Surg 196:859–863

    Google Scholar 

  44. Wysoki MG et al (1997) Necrotizing fasciitis: CT characteristics. Radiology 203:859–863

    Article  CAS  PubMed  Google Scholar 

  45. Yoneda A et al (2010) MRI can determine the adequate area for debridement in case of Fourniers gangrene. Int Surg 95:76–79

    PubMed  Google Scholar 

  46. Zimbelmann J et al (1999) Improved outcome of clindamycin with beta-lactam antibiotic treatment for invasive streptococcus pyogenes infection. Pediatr Infect Dis J 18:1096–1100

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to M. Jäger.

Ethics declarations

Interessenkonflikt

C. Scheid, M. Dudda und M. Jäger geben an, dass kein Interessenkonflikt besteht.

Dieser Beitrag beinhaltet keine von den Autoren durchgeführten Studien an Menschen oder Tieren. Alle Patienten, die über Bildmaterial oder anderweitige Angaben innerhalb des Manuskripts zu identifizieren sind, haben hierzu ihre schriftliche Einwilligung gegeben.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Scheid, C., Dudda, M. & Jäger, M. Nekrotisierende Fasziitis – eine klinische Diagnose. Orthopäde 45, 1072–1079 (2016). https://doi.org/10.1007/s00132-016-3318-x

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00132-016-3318-x

Schlüsselwörter

Keywords

Navigation