Zusammenfassung
Die schwergradige Osteoporose stellt in der instrumentierenden Wirbelsäulenchirurgie ein großes Problem dar. Neben Anschlusskyphosierungen und -frakturen sind Schraubenlockerungen und Implantatausrisse ein alltägliches Problem bei der osteoporotischen Wirbelsäule. Es ist hinreichend bekannt, dass die Knochendichte neben Schraubendicke und -länge den größten Einfluss auf die Stabilität einer Schraube hat. Bei einer schweren Osteoporose kann durch die Zementaugmentierung die Ausrissfestigkeit einer Pedikelschraube um 96–278% verbessert werden. Bis heute haben sich zwei verschiedene Vorgehensweisen etabliert: Zementierung des Wirbelkörpers vor Einbringen der Schraube in den noch weichen Zement oder Zementaugmentierung nach Einbringung einer perforierten Schraube.
Das größte Problem der Augmentierung ist das Auftreten von Leckagen. Zementleckagen können bei beiden Techniken auftreten. Bei der Augmentation über die perforierte Schraube scheint aber das Problem eine geringere Rolle zu spielen, da die Zementierung bei einer beginnenden Leckage sofort beendet werden kann. Die Revision der zementierten Schrauben stellt nach aktuellen biomechanischen Erkenntnissen kein größeres klinisches Problem dar. Auch die initial zementierten Schrauben können im Revisionsfall 1 mm dicker gewählt werden und ebenfalls erneut zementiert werden.
Abstract
Severe osteoporosis is a serious problem in the instrumentation during spine surgery. Besides kyphosis, adjacent vertebral fractures and of course pedicle screw loosening and implant pullout are frequent challenges in instrumentation of the osteoporotic spine. In addition to screw diameter and length, bone mineral density has the most important impact on the stability of a pedicle screw. In cases of severe osteoporosis cement augmentation increases the stability of a pedicle screw. Pullout force can be increased with augmentation by 96–278%. Nowadays, there are two different procedures for augmentation: cement augmentation of the vertebra before inserting the screw into the soft, fresh cement or augmentation via a perforated screw that has already been inserted.
The main problem in augmentation techniques are cement leakages. In both techniques leakages may occur. The problem of leakages seems to be less severe in the augmentation technique via the perforated screw, because cement application can be stopped immediately if the onset of leakage is noticed. Even surgical revision of cement augmented screws is not a major clinical problem based on recent biomechanical studies. The revision screw can be chosen 1 mm thicker and can be cement augmented again without technical problems.
Literatur
Blattert TR, Glasmacher S, Riesner HJ, Josten C (2009) Revision characteristics of cement-augmented, cannulated-fenestrated pedicle screws in the osteoporotic vertebral body: a biomechanical in vitro investigation. Technical note. J Neurosurg Spine 11:23–27
Bullmann V, Schmoelz W, Richter M et al (2010) Revision of cannulated and perforated cement-augmented pedicle screws: a biomechanical study in human cadavers. Spine (in press)
Burval DJ, McLain RF, Milks R, Inceoglu S (2007) Primary pedicle screw augmentation in osteoporotic lumbar vertebrae: biomechanical analysis of pedicle fixation strength. Spine 32:1077–1083
Chang MC, Liu CL, Chen TH (2008) Polymethylmethacrylate augmentation of pedicle screw for osteoporotic spinal surgery: a novel technique. Spine 33:317–324
Chen LH, Tai CL, Lai PL et al (2009) Pullout strength for cannulated pedicle screws with bone cement augmentation in severely osteoporotic bone: influences of radial hole and pilot hole tapping. Clin Biomech 24:613–618
Cook SD, Salkeld SL, Stanley T et al (2004) Biomechanical study of pedicle screw fixation in severely osteoporotic bone. Spine J 4:402–408
Daftari TK, Horton WC, Hutton WC (1994) Correlations between screw hole preparation, torque of insertion, and pullout strength for spinal screws. J Spinal Disord Tech 7:139–145
Derincek A, Wu C, Mehbod A, Transfeldt EE (2006) Biomechanical comparison of anatomic trajectory pedicle screw versus injectable calcium sulfate graft-augmented pedicle screw for salvage in cadaveric thoracic bone. J Spinal Disord Tech 19:286–291
Frankel BM, D’Agostino S, Wang C (2007) A biomechanical cadaveric analysis of polymethylmethacrylate-augmented pedicle screw fixation. J Neurosurg Spine 7:47–53
Frankel BM, Jones T, Wang C (2007) Segmental polymethylmethacrylate-augmented pedicle screw fixation in patients with bone softening caused by osteoporosis and metastatic tumor involvement: a clinical evaluation. Neurosurgery 61:531–538
Hackenberg L, Link T, Liljenqvist U (2002) Axial and tangential fixation strength of pedicle screws versus hooks in the thoracic spine in relation to bone mineral density. Spine 27:937–942
Halvorson TL, Kelley LA, Thomas KA et al (1994) Effects of bone mineral density on pedicle screw fixation. Spine 19:2415–2420
Hirano T, Hasegawa K, Takahashi HE et al (1997) Structural characteristics of the pedicle and its role in screw stability. Spine (Phila Pa 1976) 22:2504–2510
Inceoglu S, Ferrara L, McLain RF (2004) Pedicle screw fixation strength: pullout versus insertional torque. Spine J 4:513–518
Kiner DW, Wybo CD, Sterba W et al (2008) Biomechanical analysis of different techniques in revision spinal instrumentation: larger diameter screws versus cement augmentation. Spine 33:2618–2622
Lehman RA Jr, Kuklo TR (2003) Use of the anatomic trajectory for thoracic pedicle screw salvage after failure/violation using the straight-forward technique: a biomechanical analysis. Spine 28:2072–2077
McKoy BE, An YH (2000) An injectable cementing screw for fixation in osteoporotic bone. J Biomed Mater Res A 53:216–220
McLain RF, Fry MF, Moseley TA, Sharkey NA (1995) Lumbar pedicle screw salvage: pullout testing of three different pedicle screw designs. J Spinal Disord 8:62–68
Myers BS, Belmont PJ Jr, Richardson WJ et al (1996) The role of imaging and in situ biomechanical testing in assessing pedicle screw pull-out strength. Spine 21:1962–1968
Okuyama K, Sato K, Abe E et al (1993) Stability of transpedicle screwing for the osteoporotic spine. An in vitro study of the mechanical stability. Spine 18:2240–2245
Pfeifer BA, Krag MH, Johnson C (1994) Repair of failed transpedicle screw fixation. A biomechanical study comparing polymethylmethacrylate, milled bone, and matchstick bone reconstruction. Spine 19:350–353
Polly DW Jr, Orchowski JR, Ellenbogen RG (1998) Revision pedicle screws. Bigger, longer shims–what is best? Spine 23:1374–1379
Renner SM, Lim TH, Kim WJ et al (2004) Augmentation of pedicle screw fixation strength using an injectable calcium phosphate cement as a function of injection timing and method. Spine 29:212–216
Rohmiller MT, Schwalm D, Glattes RC et al (2002) Evaluation of calcium sulfate paste for augmentation of lumbar pedicle screw pullout strength. Spine J 2:255–260
Sarzier JS, Evans AJ, Cahill DW (2002) Increased pedicle screw pullout strength with vertebroplasty augmentation in osteoporotic spines. J Neurosurg 96:309–312
Soshi S, Shiba R, Kondo H, Murota K (1991) An experimental study on transpedicular screw fixation in relation to osteoporosis of the lumbar spine. Spine 16:1335–1341
Tan JS, Singh S, Zhu QA et al (2008) The effect of cement augmentation and extension of posterior instrumentation on stabilization and adjacent level effects in the elderly spine. Spine 33:2728–2740
Taniwaki Y, Takemasa R, Tani T et al (2003) Enhancement of pedicle screw stability using calcium phosphate cement in osteoporotic vertebrae: in vivo biomechanical study. J Orthop Sci 8:408–414
Wittenberg RH, Lee KS, Shea M et al (1993) Effect of screw diameter, insertion technique, and bone cement augmentation of pedicular screw fixation strength. Clin Orthop Relat Res 278–287
Wuisman PI, Van Dijk M, Staal H, Van Royen BJ (2000) Augmentation of (pedicle) screws with calcium apatite cement in patients with severe progressive osteoporotic spinal deformities: an innovative technique. Eur Spine J 9:528–533
Yazu M, Kin A, Kosaka R et al (2005) Efficacy of novel-concept pedicle screw fixation augmented with calcium phosphate cement in the osteoporotic spine. J Orthop Sci 10:56–61
Yerby SA, Toh E, McLain RF (1998) Revision of failed pedicle screws using hydroxyapatite cement. A biomechanical analysis. Spine 23:1657–1661
Zindrick MR, Wiltse LL, Widell EH et al (1986) A biomechanical study of intrapeduncular screw fixation in the lumbosacral spine. Clin Orthop Relat Res 99–112
Interessenkonflikt
Der korrespondierende Autor weist auf folgende Beziehung hin: Frau PD Dr. V. Bullmann ist als Referentin für die Firma Ulrich medical® und Depuy Spine tätig.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Bullmann, V., Liljenqvist, U., Rödl, R. et al. Pedikelschraubenaugmentation aus biomechanischer Sicht. Orthopäde 39, 673–678 (2010). https://doi.org/10.1007/s00132-010-1602-8
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00132-010-1602-8