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Effect of Sub-lethal Concentrations of Endosulfan on Phagocytic and Hematological Parameters in Nile Tilapia (Oreochromis niloticus)

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Abstract

The effect of endosulfan (6,7,8,9,10,10-hexachloro-1,5,5a,6,9,9a-hexahydro-6,9-methano-2,4,3-benzodioxathiepin-3-oxide), an organochlorine pesticide, was evaluated on phagocytic (phagocytic index and percentage of active cells) and hematological parameters in Nile tilapia. Experimental data showed that an acute exposure to endosulfan (4.0 and 7.0 μg/L) induces a significant decrease in the phagocytic index and the percentage of active cells in peripherical blood of Nile tilapia. However, hemoglobin concentration (Hb), hematocrit (Hto), red blood cell count (RBC), mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH), and mean corpuscular hemoglobin concentration (MCHC) were not significantly altered in fish exposed to endosulfan compared with control group.

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References

  • Ainsworth AJ, Dexiang C, Waterstrat PR Greenway T (1991) Effect of temperature on the immune system of channel catfish (Ictalurus punctatus)-I. Leucocyte distribution and phagocyte function in the anterior kidney at 10°C. Comp Biochem Physiol 100A:907–912

    Article  Google Scholar 

  • Ayub S, Verna J, Das N (2003) Effect of endosulfan and malathion on lipid peroxidation, nitrite and TNF-α release by rat peritoneal macrophages. Int Immunopharmacol 3:1819–1828

    Article  CAS  Google Scholar 

  • Caldas ED, Coelho R, Souza LCR, Siba SC (1999) Organochlorine pesticides in water, sediment, and fish of Paranoá Lake of Brasilia, Brazil. Bull Environ Contam Toxicol 62:199–206

    Article  CAS  Google Scholar 

  • Casas-Sólis J, Santerre A, Girón-Pérez MI, Reynoso-Orozco R, Zaitseva G (2007) Comparative study of phagocytic activity and lymphoproliferative response in five varieties of tilapia (Oreochromis spp.) J Fish Biol 71:1541–1545

    Article  Google Scholar 

  • Cox C, Surgan M (2006) Unidentified inert ingredients in pesticides: implications for human and environmental health. Environ Health Persp 114:1803–1806

    CAS  Google Scholar 

  • Fitzsimmons K (2000) Future trends of tilapia aquaculture in the Americas. In Costa-Pierce BA, Rakocy JE (eds) Tilapia aquaculture in the Americas, vol 2. The World Aquaculture Society, Baton Rouge, Louisiana, pp 252–264

  • Girón-Pérez MI, Barcelos-García R, Vidal-Chavez ZG, Romero-Bañuelos CA, Robledo-Marenco ML (2006) Effect of chlorpyrifos on the hematology and phagocytic activity of Nile tilapia cells (Oreochromis niloticus). Toxicol Mech Methods 16:495–499

    Article  Google Scholar 

  • Harford AJ, O’Halloran K, Wright PFA (2005) The effect of in vitro pesticide exposures on the phagocytic function of four native Australian freshwater fish. Aquat Toxicol 75:330–342

    Article  CAS  Google Scholar 

  • Hemmer MJ, Hemmer BL, Bowman CJ, Kroll KJ, Folmar LC, Marcovich D, Hoglund MD, Denslow ND (2001) Effects of p-nonylphenol, methoxychlor and endosulfan on vitellogenin induction and expression in sheephead minnow (Cyprinodon variegates). Environ Toxicol Chem 20:336–343

    Article  CAS  Google Scholar 

  • Jenkins F, Smith J, Hajanna B, Shameen H, Umadevi K, Sandhya V, Madhavi R (2003) Effect of sub-lethal concentrations of endosulfan on hematological and serum biochemical parameters in the carp Cyprinus carpio Bull Environ Contam Toxicol 70:993–997

    Article  CAS  Google Scholar 

  • Luskova V (1996) Annual cycles and normal values of hematological parameters in fishes. Acta Sci Nat Brno 31:1–70

    Google Scholar 

  • Muñiz JMI, Ribeiro KS, de Paula CVN, Junqueira LF (2006) Effects of pravastatin on the in vitro phagocytic function and hydrogen peroxide production by monocytes of healthy individuals. Int Immunopharmacol 6:53–60

    Article  Google Scholar 

  • Neumann NF, Stafford JL, Barreda D, Ainsworth AJ, Belosevic M (2001) Antimicrobial mechanisms of fish phagocytic and their role in host defense. Dev Comp Immunol 25:807–825

    Article  CAS  Google Scholar 

  • Sunderam RIM, Thompson GB, Chapman JC, Cheng DMH (1994) Acute and chronic toxicity of endosulfan to two Australian cladocerans and their applicability in deriving water quality criteria. Environ Toxicol Chem 27:541–545

    CAS  Google Scholar 

  • Van Dyk LP, Greeff CG (1977) Endosulfan pollution of rivers and streams in the Loskop dam cotton growing area. Agrochemophysia 9:71–75

    Google Scholar 

  • Watanuki N, Takahashi A, Yasuda A, Sakai M (1999) Kidney leucocytes of rainbow trout, Oncorhynchus mykiss, are activated by intraperitoneal injection of β-endorphin. Vet Immunol Immunopatol 71:89–97

    Article  CAS  Google Scholar 

  • Zhou HY, Cheung RYH, Wong MH (1999) Residues of organochlorines in sediments and tilapia collected from inland water systems of Hong Kong. Arch Environ Con Toxicol 36:424–431

    Article  CAS  Google Scholar 

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Acknowledgments

This research was partially supported by University of Nayarit. We gratefully acknowledge SAGARPA Nayarit Delegation, particularly Julio Alfonso Gómez Gurrola, for their help. The authors wish to thank Anne Santerre Lucas and Jesús Velázquez Fernández for their help in reviewing the manuscript.

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Authors and Affiliations

  1. Laboratorio de Inmunotoxicología, Posgrado CBAP, Universidad Autónoma de Nayarit, Cd. de la Cultura Amado Nervo, Tepic, Nayarit, 63000, Mexico

    M. I. Girón-Pérez

  2. Laboratorio de Contaminación y Toxicología Ambiental, Universidad Autónoma de Nayarit, Cd. de la Cultura Amado Nervo, Tepic, Nayarit, 63000, Mexico

    M. Montes-López, L. A. García-Ramírez, C. A. Romero-Bañuelos & M. L. Robledo-Marenco

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  1. M. I. Girón-Pérez
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  2. M. Montes-López
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  3. L. A. García-Ramírez
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  4. C. A. Romero-Bañuelos
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  5. M. L. Robledo-Marenco
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Correspondence to M. I. Girón-Pérez.

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Girón-Pérez, M.I., Montes-López, M., García-Ramírez, L.A. et al. Effect of Sub-lethal Concentrations of Endosulfan on Phagocytic and Hematological Parameters in Nile Tilapia (Oreochromis niloticus). Bull Environ Contam Toxicol 80, 266–269 (2008). https://doi.org/10.1007/s00128-008-9358-0

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  • DOI: https://doi.org/10.1007/s00128-008-9358-0

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