Skip to main content

Advertisement

Log in

Predictors of suicidality in depressive spectrum disorders in the general population: results of the Netherlands Mental Health Survey and Incidence Study

  • Original Paper
  • Published:
Social Psychiatry and Psychiatric Epidemiology Aims and scope Submit manuscript

Abstract

Objective

The aim was to assess determinants of suicidality (suicidal ideation and suicide attempts) in a general population cohort with depressive spectrum disorders, and to compare determinants for suicidal ideation and determinants for suicide attempts in this cohort.

Method

The Netherlands Mental Health Survey and Incidence Study is a epidemiologic survey in the adult population (N = 7,076), using the Composite International Diagnostic Interview (CIDI).

Results

In a cohort of 586 persons with a depressive spectrum disorder, 97 (16.6%) reported suicidal ideation and 19 (3.2%) suicide attempts in a period of 2 years. In a multivariate model, male gender (OR 0.54, 95% CI 0.30–0.99, p = 0.05), longer (>13 months) duration of depression (OR 2.86, 95%CI 1.21–6.73, p = 0.02; OR 2.71, 95% CI 1.24–5.91, p = 0.01), anhedonia (OR 2.00, 95% CI 1.01–5.91, p = 0.05), feeling worthless (OR 1.99, 95% CI 1.05–3.74, p = 0.03), comorbid anxiety (OR 2.46, 95% CI 1.38–4.40, p < 0.01), previous suicidal ideation (OR 3.50, 95% CI 1.96–6.24, p < 0.001) and use of professional care (OR 1.96, 95% CI 1.01–3.79, p = 0.05) were significantly related to suicidality. Determinants of suicidal ideation differed from determinants of suicide attempts.

Limitations

Suicidality (and not actual suicides) was assessed with only two questions from the CIDI and some determinants for suicidality were assessed in the same time period as suicidality.

Conclusions

Features of depression were the most important determinants of suicidality in a depressive spectrum cohort. Determinants for suicidal ideation differed from suicide attempts. These findings could be helpful in identifying those who need more intense treatment strategies in order to prevent suicidality and eventually suicide.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. American Psychiatric Association (1987) Diagnostic and Statistical Manual of Mental disorders (3rd edn, revised) (DSM-III-R). APA, Washington, DC

    Google Scholar 

  2. Angst J, Sellaro R, Merikangas KR (2000) Depressive spectrum diagnoses. Compr Psychiatry 41:39–47

    Article  CAS  PubMed  Google Scholar 

  3. Bernal M, Haro JM, Bernert S, Brugha T, de Graaf R, Bruffaerts R, The ESEMED/MHEDEA Investigators et al (2007) Risk factors for suicidality in Europe: results from the ESEMED study. J Affect Disord 101:27–34

    Article  CAS  PubMed  Google Scholar 

  4. Bijl RV, van Zessen G, Ravelli A (1998) The Netherlands Mental Health Survey and Incidence Study (NEMESIS). Soc Psychiatry Psychiatr Epidemiol 33:581–586

    Article  CAS  PubMed  Google Scholar 

  5. Brent D (2007) Antidepressant and suicidal behaviour: cause or cure? Am J Psychiatry 164:989–991

    Article  PubMed  Google Scholar 

  6. Bolton JM, Shay-Lee B, Enns MW, Cox BJ, Sareen J (2008) Exploring the correlates of suicide attempts among individuals with major depressive disorder: findings from the national epidemiologic survey on alcohol and related conditions. J Clin Psychiatry 69:1139–1149

    Article  PubMed  Google Scholar 

  7. Bostwick JM, Pankratz VS (2000) Affective disorders and suicide risk: a re-examination. Am J Psychiatry 157:1925–1932

    Article  CAS  PubMed  Google Scholar 

  8. Brown GW, Harris TO (1987) Social origins of depression: a study of psychiatric disorder in women. Tavistock, London

    Google Scholar 

  9. Chen YW, Dilsaver SC (1996) Lifetimes rates of suicide attempts among subjects with bipolar and unipolar disorders relative to subjects with other Axis I disorders. Biol Psychiatry 39:896–899

    Article  CAS  PubMed  Google Scholar 

  10. Casey P, Dunn G, Kelly BD, Lehtinen V, Dalgard OS, Dowrick C, Ayuso-Mateos JL (2008) The prevalence of suicidal ideation in the general population: results from the Outcome of Depression International network (ODIN) study. Soc Psychiatry Psychiatr Epidemiol 43:299–304

    Article  PubMed  Google Scholar 

  11. Cuijpers P, Smit F, van Straten A (2007) Psychological treatments of subthreshold depression: a meta-analytic review. Acta Psychiatr Scand 115:434–441

    Article  CAS  PubMed  Google Scholar 

  12. Dennis M, Baillon S, Brugha T, Lindesay J, Stewart R, Meltzer H (2007) The spectrum of suicidal ideation in Great Britain: comparison across a 16–74 age range. Psychol Med 37:795–805

    Article  PubMed  Google Scholar 

  13. Doeglas D, Suurmeijer T, Briancon S, Moum T, Krol B, Bjelle A et al (1996) An international study on measuring social support: interactions and satisfaction. Soc Sci Med 43:389–1397

    Article  Google Scholar 

  14. Fairweather-Schmidt AK, Anstey KJ, Mackinnon AJ (2009) Is suicidality distinguishable from depression? Evidence from a community-based sample. Aust N Z J Psychiatry 43:208–215

    Article  PubMed  Google Scholar 

  15. Gibbons RD, Brown CH, Hur K, Marcus SM, Bhaumik DK, Mann JJ (2007) Relationship between antidepressants and suicide attempts: an analysis of the veteran health administration data sets. Am J Psychiatry 164:1044–1049

    Article  PubMed  Google Scholar 

  16. de Graaf R, Bijl RV, Smit F (2000) Psychiatric and sociodemographic predictors of attrition in a longitudinal study: the Netherlands Mental Health Survey and Incidence Study (NEMESIS). Am J Epidemiol 152:1039–1047

    Article  PubMed  Google Scholar 

  17. Graaf R, de Bijl RV, Vollebergh WAM (2000) Response and non-response third wave: the Netherlands Mental Health Survey and Incidence Study (NEMESIS) Technical Report no. 11. Trimbos-institute, Utrecht

    Google Scholar 

  18. Have ten M, Graaf de R, Dorsselaer van S, Verdurmen J, van’t Land H, Vollebergh W, Beekman A (2009) Incidence and course of suicidal ideation and suicide attempts in the general population. Can J Psychiatry (in press)

  19. Hegerl U, Althaus D, Schmidtke A, Niklewiski G (2006) The alliance against depression: a 2-year evaluation of a community-based intervention to reduce suicidality. Psychol Med 36:1225–1233

    Article  PubMed  Google Scholar 

  20. Henriksson S, Isacsson G (2006) Increased antidepressant use and fewer suicides in Jamtland country, Sweden, after a primary care educational program on the treatment of depression. Acta Psychiatr Scand 114:159–167

    Article  CAS  PubMed  Google Scholar 

  21. Hintikaa J, Koivumaa-Honkanen H, Lehto SM, Tolmunen T, Honkalampi K, Haatainen K, Viinamaki H (2009) Are factors associated with suicidal ideation true risk factors? A 3-year prospective follow-up study in a general population. Soc Psychiatry Psychiatr Epidemiol 44:29–33

    Article  Google Scholar 

  22. Isacsson G, Bergman U, Rich CL (1996) Epidemiological data suggest antidepressant reduce suicide risk among depressives. J Affect Disord 41:1–8

    Article  CAS  PubMed  Google Scholar 

  23. Keilp JG, Gorlyn M, Oquendo MA, Brodsky B, Ellis SP, Stanley B, Mann JJ (2006) Aggressiveness, not impulsiveness or hostility, distinguishes suicide attempters with major depression. Psychol Med 36:1779–1788

    Article  PubMed  Google Scholar 

  24. Kuo WH, Gallo JJ, Eaton WW (2004) Hopelessness, depression, substance disorder and suicidality, a 13 year community based study. Soc Psychiatry Psychiatr Epidemiol 39:497–501

    Article  PubMed  Google Scholar 

  25. Luoma JB, Martin CE, Pearson LJ (2002) Contact with mental health and primary care providers before suicide: a review of the evidence. Am J Psychiatry 159:909–916

    Article  PubMed  Google Scholar 

  26. Lyketsos CG, Nestadt G, Cwi J (1994) The life chart interview: a standardized method to describe the course of psychopathology. Int J Methods Psychiatr Res 4:143–155

    Google Scholar 

  27. McCullough JP (2000) Treatment for chronic depression. Cognitive behavorial analysis system of psychotherapy (CBASP). Guilford Press, New York

    Google Scholar 

  28. Mulder RT, Joyce PR, Frampton CMA, Luty SE (2008) Antidepressant treatment is associated with a reduction in suicidal ideation and suicide attempts. Acta Psychiatr Scand 118:116–122

    Article  CAS  PubMed  Google Scholar 

  29. Neeleman J, de Graaf R, Vollebergh W (2004) The suicidal process; prospective comparison between early and later stages. J Aff Dis 82:43–52

    Article  Google Scholar 

  30. Ormel H (1980) Moeite met leven of een moeilijk leven. Thesis. University Groningen

  31. Oquendo MA, Currier D, Mann JJ (2006) Prospective studies of suicidal behaviour in major depressive and bipolar disorders: what is the evidence for predictive risk factors? Review article. Acta Psychiatr Scand 114:151–158

    Article  CAS  PubMed  Google Scholar 

  32. Pearlin IP, Schooler C (1978) The structure of coping. J Health Soc Behav 19:2–21

    Article  CAS  PubMed  Google Scholar 

  33. Smeets RMW, Dingemans PMAJ (1993) Composite International Diagnostic Interview (CIDI), version 1.1. World Health Organization, Amsterdam/Geneva

    Google Scholar 

  34. Smolders M, Laurant M, Akkermans R, Wensing M, Grol R (2008) GP’s assessment of suicide risk in depressed patients. Prim Care Comm Psychiatry 13:138–140

    Google Scholar 

  35. Spijker J, Bijl RV, de Graaf R, Beekman ATF, Ormel H, Nolen WA (2002) Duration of major depressive episodes in the general population. Results from the Netherlands Mental Health Survey and Incidence Study (NEMESIS). Br J Psychiatry 181:208–213

    Article  PubMed  Google Scholar 

  36. Spijker J, de Graaf R, Bijl RV, Beekman ATF, Ormel J, Nolen WA (2004) Determinants of persistence of major depressive episodes in the general population. Results from the Netherlands Mental Health Survey and Incidence Study (NEMESIS). J Affect Disord 81:231–240

    Article  PubMed  Google Scholar 

  37. Suurmeijer TP, Doeglas DM, Briancon S, Krijnen WP, Krol B, Bjelle A et al (1996) The measurement of social support in the ‘European Research on Incapacitating Diseases and Social Support’: the development of the Social Support Questionnaire for Transactions (SSQT). Soc Sci Med 40:1221–1229

    Article  Google Scholar 

  38. Wittchen HU (1994) Reliability and validity studies of the WHO–CIDI: a critical review. J Psychiatr Res 28:57–84

    Article  CAS  PubMed  Google Scholar 

  39. World Health Organization (1990) Composite Diagnostic Interview (CIDI), version 1.0. World Health Organization, Geneva

    Google Scholar 

Download references

Acknowledgments

NEMESIS is supported by the Netherlands Ministry of Health, Welfare and Sport (VWS), the Medical Sciences Department of the Netherlands Organisation for Scientific Research (NWO), and the National Institute for Public Health and Environment (RIVM).

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Jan Spijker.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Spijker, J., de Graaf, R., ten Have, M. et al. Predictors of suicidality in depressive spectrum disorders in the general population: results of the Netherlands Mental Health Survey and Incidence Study. Soc Psychiat Epidemiol 45, 513–521 (2010). https://doi.org/10.1007/s00127-009-0093-6

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00127-009-0093-6

Keywords

Navigation