Skip to main content

Advertisement

Log in

Assessment of physical etiologies for mood and anxiety disorders in structured diagnostic interviews

  • ORIGINAL PAPER
  • Published:
Social Psychiatry and Psychiatric Epidemiology Aims and scope Submit manuscript

Abstract

Background

Structured diagnostic inter- views include items that evaluate physical etiologies for mood and anxiety disorders. The objective of this article was to assess the impact of such items.

Method

A mental health survey in Canada collected data from n = 36,984 household residents. The lifetime prevalence of mood and anxiety disorders was calculated with and without exclusions due to physical causes.

Results

Approximately 10% of subjects with a lifetime depressive disorder reported that all of their episodes were due to one or more physical cause. Many of the reported etiologies were implausible given the DSM-IV requirement that the disturbance be a “direct physiological consequence” of the physical cause. The results were similar for manic episodes and anxiety disorders.

Conclusions

Structured diagnostic interviews assess physical etiologies in ways that are subject to inconsistency and inaccuracy. Physical etiology items may bias estimates by introducing etiological opinions into the assessment of disorder frequency.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. American Psychiatric Association (2000) Diagnostic and Statistical Manual of Mental Disorders (DSM-IV-TR). American Psychiatric Association, Washington

    Google Scholar 

  2. American Psychiatric Association (2002) Diagnostic and Statistical Manual of Mental Disorders (DSM-IV-TR). American Psychiatric Association, Washington, DC

    Google Scholar 

  3. Bair MJ, Robinson RL, Katon W, Kroenke K (2003) Depression and pain comorbidity. A literature revew. Arch Intern Med 163:2433–2445

    Article  PubMed  Google Scholar 

  4. Bunevicius R, Velickiene D, Prange AJ Jr (2005) Mood and anxiety disorders in women with treated hyperthyroidism and ophthalmopathy caused by Graves’ disease. Gen Hosp Psychiatry 27:133–139

    Article  PubMed  Google Scholar 

  5. Burmeister LA, Ganguli M, Dodge HH, Toczek T, DeKosky ST, Nebes RD (2001) Hypothyroidism and cognition: Preliminary evidence for a specific defect in memory. Thyroid 11:1177–1185

    Article  PubMed  CAS  Google Scholar 

  6. Carpenter KM, Hasin DS, Allison DB, Faith MS (2000) Relationships between obesity and DSM-IV major depressive disorder, suicide ideation, and suicide attempts: results from a general population study. Am J Public Health 90:251–257

    Article  PubMed  CAS  Google Scholar 

  7. Constant EL, Adam S, Bruyer SR, Seghers A, Daumerie C (2005) Anxiety and depression, attention and executive functions in hypothyroidism. J Int Neuropsychol Soc 11:535–544

    Article  PubMed  CAS  Google Scholar 

  8. Engum A, Bjøro T, Mykletun A, Dahl AA (2002) An association between depression, anxiety and thyroid function—a clinical fact or an artifact? Acta Psychiatr Scand 106:27–34

    Article  PubMed  CAS  Google Scholar 

  9. Engum A, Bjøro T, Mykletun A, Dahl AA (2005) Thyroid autoimmunity, depression and anxiety; are there any connections? An epidemiological study of a large population. J Psychosom Res 59:263–268

    Article  PubMed  Google Scholar 

  10. ESEMeD/MHEDEA 2000 Investigators (2004) Prevalence of mental disorders in Europe: results from the European Study of the Epidemiology of Mental Disorders (ESEMeD) project. Acta Psychiatr Scand 109(Suppl. 420):21–27

    Article  Google Scholar 

  11. Forman-Hoffman V, Philibert RA (2006) Lower TSH and higher T4 levels are associated with current depressive syndrome in young adults. Acta Psychiatr Scand 114:132–139

    Article  PubMed  CAS  Google Scholar 

  12. Gravel R, Béland Y (2005) The Canadian Community Health Survey: Mental Health and Well-Being. Can J Psychiatry 50:573–579

    PubMed  Google Scholar 

  13. Holland JC, Korzun AH, Tross S, Silberfarb P, Perry M, Comis R, Oster M (1986) Comparative psychological disturbance in patients with pancreatic and gastric cancer. Am J Psychiatry 143:982–986

    PubMed  CAS  Google Scholar 

  14. Joffe RT, Rubinow DR, Denicoff KD, Maher M, Sindelar WF (1986) Depression and carcinoma of the pancreas. Gen Hosp Psychiatry 8:241–245

    Article  PubMed  CAS  Google Scholar 

  15. Johnston E, Johnson S, McLeod P, Johnston M (2004) The relation of body mass index to depressive symptoms. Can J Public Health 95:179–183

    PubMed  Google Scholar 

  16. Kessler RC, Berglund P, Demler O, Jin R, Koretz D, Merikangas KR, Rush JA, Waters EE, Wang PS (2003) The epidemiology of major depressive disorder: results from the National Comorbidity Survey Replication (NCS-R). JAMA 289:3095–3105

    Article  PubMed  Google Scholar 

  17. Kessler RC, Ustun TB (2004) The World Mental Health (WMH) Survey Initiative Version of the World Health Organization (WHO) Composite International Diagnostic Interview (CIDI). Int J Methods Psychiatr Res 13:83–121

    Google Scholar 

  18. Lindeman S, Hämäläinen J, Isometsä E, Kaprio J, Poikolainen K, Heikkinen M, Aro H (2000) The 12-month prevalence and risk factors for major depressive episode in Finland: representative sample of 5993 adults. Acta Psychiatr Scand 102:178–184

    Article  PubMed  CAS  Google Scholar 

  19. McIntyre RS, Konarksi JZ, Wilkins K, Soczynska JK, Kennedy SH (2006) Obesity in bipolar disorder and major depressive disorder: results from a national community health survey on mental health and well-being. Can J Psychiatry 51:274–280

    PubMed  Google Scholar 

  20. Patten SB, Barbui C (2004) Drug-induced depression: a systematic review to inform clinical practice. Psychother Psychosom 73:207–215

    Article  PubMed  Google Scholar 

  21. Peeters L, Andrews G (1995) Procedural validity of the computerized version of the Composite International Diagnostic Interview (CIDI-Auto) in anxiety disorders. Psychol Med 25:1269–1280

    Article  Google Scholar 

  22. Placidi GPA, Boldrini M, Patronelli A, Fiore E, Chiovato L, Perugi G, Marazziti D (1998) Prevalence of psychiatric disorders in thyroid diseased patients. Neuropsychobiology 38:222–225

    Article  PubMed  CAS  Google Scholar 

  23. Roberts LM, Pattison H, Roalfe A, Franklyn J, Wilson S, Hobbs R, Parle JV (2006) Is subclinical thyroid dysfunction in the elderly associated with depression or cognitive dysfunction? Ann Int Med 145:573–581

    PubMed  Google Scholar 

  24. Rothman KJ (2002) Epidemiology in clinical settings. Epidemiology. An introduction. Oxford University Press, Oxford: 198–217

    Google Scholar 

  25. Rothman KJ (1976) Causes. Am J Epidemiol 104:587–592

    PubMed  CAS  Google Scholar 

  26. SAS Institute Inc. (8.1). 2000. Cary, NC, SAS Institute Inc.

  27. Simon GE, Von Korff M, Saunders K, Miglioretti DL, Crane PK, van Belle G, Kessler RC (2006) Association between obesity and psychiatric disorders in the US adult population. Arch Gen Psychiatry 63:824–830

    Article  PubMed  Google Scholar 

  28. Tagay S, Herpertz S, Langkafel M, Erim Y, Freudenberg L, Schöpper N, Bockisch A, Senf W, Görges R (2005) Health-related quality of life, anxiety and depression in thyroid cancer patients under short-term hypothyroidism and TSH-suppressive levothyroxine treatment. Eur J Epidemiol 153:755–763

    CAS  Google Scholar 

  29. Trzepacz PT, McCue M, Klein I, Levey GS, Greenhouse J (2006) A psychiatric and neuropsychological study of patients with untreated Graves’ disease. Gen Hosp Psychiatry 10:49–55

    Article  Google Scholar 

  30. Whybrow PC, Prange AJ, Treadway CR (1969) Mental changes accompanying thryoid gland dysfunction. Arch Gen Psychiatry 20:48–63

    PubMed  CAS  Google Scholar 

  31. World Health Organization (1994) The Composite International Diagnostic Interview, Version 1.1, Researcher’s Manual. World Health Organization, Geneva

    Google Scholar 

Download references

Acknowledgments

This project was funded by a grant from the Institute for Health Economics (http://www.ihe.ab.ca). Dr. Patten is a Health Scholar with the Alberta Heritage Foundation for Medical Research and a Fellow with the Institute of Health Economics.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Scott B. Patten MD, PhD.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Patten, S., Williams, J. Assessment of physical etiologies for mood and anxiety disorders in structured diagnostic interviews. Soc Psychiat Epidemiol 42, 462–466 (2007). https://doi.org/10.1007/s00127-007-0195-y

Download citation

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00127-007-0195-y

Key words

Navigation