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Assessment of ancestry probabilities in the presence of genotyping errors

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Abstract

This paper extends an approach for estimating the ancestry probability, the probability that an inbred line is an ancestor of a given hybrid, to account for genotyping errors. The effect of such errors on ancestry probability estimates is evaluated through simulation. The simulation study shows that if misclassification is ignored, then ancestry probabilities may be slightly overestimated. The sensitivity of ancestry probability calculations to the assumed genotyping error rate is also assessed.

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Authors and Affiliations

  1. Department of Mathematics and Statistics, The University of West Florida, Pensacola, FL, 32514, USA

    Hongmei Zhang

  2. Department of Statistics, The University of California, Irvine, CA, 92697, USA

    Hal Stern

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  1. Hongmei Zhang
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  2. Hal Stern
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Correspondence to Hongmei Zhang.

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Communicated by A. E. Melchinger

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Zhang, H., Stern, H. Assessment of ancestry probabilities in the presence of genotyping errors. Theor Appl Genet 112, 472–482 (2006). https://doi.org/10.1007/s00122-005-0148-3

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  • DOI: https://doi.org/10.1007/s00122-005-0148-3

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