Zusammenfassung
In dieser Übersicht werden neue Erkenntnisse zum Nierenzellkarzinom (NZK) dargestellt. Die Suche nach neuen Zielstrukturen der Target-Therapie sowie diagnostischen und prognostischen Markern bleibt nach wie vor ein begehrtes Forschungsgebiet. Es wird der Einsatz sowohl bereits etablierter als auch neuer Therapeutika beim metastasierten NZK (mNZK) sowie die immer großzügiger gestellte Indikation zur organerhaltenden Nierentumorchirurgie untersucht. Das Ansprechen auf die systemische Therapie beim mNZK wird weiterhin auch in definierten Subpopulationen evaluiert.
Abstract
This overview presents new insights into renal cell carcinoma (RCC). The search for new target structures for targeted therapy as well as diagnostic and prognostic markers continues to remain a desirable area of research. Investigations are focusing on the use of well-established and new therapeutic agents for metastatic RCC and an increasingly liberal indication for organ-sparing surgery for renal tumors. The response to systemic treatment in metastatic RCC is also being evaluated in defined subpopulations.
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Tsaur, I., Haferkamp, A. Nierenzellkarzinom: Was gibt es Neues im Jahr 2010?. Urologe 50 (Suppl 1), 216 (2011). https://doi.org/10.1007/s00120-011-2676-6
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DOI: https://doi.org/10.1007/s00120-011-2676-6