Skip to main content
SpringerLink
Log in

Testikulärer Keimzelltumor und Sarkoidose

Eine diagnostische Herausforderung

Coincidence of testicular germ cell tumor and sarcoidosis

A diagnostic challenge

  • Kasuistiken
  • Published:
Der Urologe Aims and scope Submit manuscript

Zusammenfassung

In Fallberichten und kleinen Fallserien wurden bislang 66 Patienten mit Sarkoidose und Hodentumor in der Literatur dokumentiert. Anhand von 3 weiteren Fallberichten aus unserer Klinik wird die potentielle Problematik eines simultanen Auftretens von Sarkoidose und testikulären Keimzelltumor in Bezug auf die radiologischen und pathologischen Befunde diskutiert. Die Sarkoidose, die mit einem Keimzelltumor assoziiert sein kann, sollte stets in die Differentialdiagnose integriert werden.

Abstract

Several case reports and small case series have described a total of 66 patients with sarcoidosis and testicular cancer so far. This report describes three additional cases. We highlight the association of sarcoidosis and testicular cancer and comment on the potential impact of this connection on the interpretation of the radiological and pathological findings in suspected cancer relapse. Sarcoidosis, a condition that can be combined with testicular cancer, should always be considered in the differential diagnosis.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Abb. 1
Abb. 2
Abb. 3
Abb. 4

Literatur

  1. Brincker H, Wilbek E (1974) The incidence of malignant tumours in patients with respiratory sarcoidosis. Br J Cancer 29(3): 247–251

    PubMed  Google Scholar 

  2. Brincker H (1986) Sarcoid reactions in malignant tumours. Cancer Treat Rev 13(3): 147–156

    Article  PubMed  Google Scholar 

  3. Brincker H, Pedersen NT (1991) Immunohistologic separation of B-cell-positive granulomas from B-cell-negative granulomas in paraffin-embedded tissues with special reference to tumor-related sarcoid reactions. APMIS 99(3): 282–290

    PubMed  Google Scholar 

  4. Colebunders R, Bultinck J, Servais J, Denis L (1984) A patient with testis seminoma, sarcoidosis, and neutropenic enterocolitis. Hum Pathol 15(4): 394–396

    PubMed  Google Scholar 

  5. Gels ME, Hoekstra HJ, Sleijfer DT et al. (1995) Detection of recurrence in patients with clinical stage I nonseminomatous testicular germ cell tumors and consequences for further follow-up: a single-center 10-year experience. J Clin Oncol 13(5): 1188–1194

    PubMed  Google Scholar 

  6. Karapetis CS, Strickland AH, Yip D et al. (2001) PET and PLAP in suspected testicular cancer relapse: beware sarcoidosis. Ann Oncol 12(10): 1485–1488

    Article  PubMed  Google Scholar 

  7. Klumpen HJ, Westermann AM (2004) Diagnostic dilemma in a man with seminoma. Lancet 364(9452): 2230

    Article  PubMed  Google Scholar 

  8. Rayson D, Burch PA, Richardson RL (1998) Sarcoidosis and testicular carcinoma. Cancer 83(2): 337–343

    Article  PubMed  Google Scholar 

  9. SultanAli I, Zaman M, Yende S (2005) Sarcoidosis mimicking disseminated testicular cancer. South Med J 98(9): 935–936

    Article  PubMed  Google Scholar 

  10. Tjan-Heijnen VC, Vlasveld LT, Pernet FP, Pauwels P, De Mulder PH (1998) Coincidence of seminoma and sarcoidosis: a myth or fact? Ann Oncol 9(3): 321–325

    Article  PubMed  Google Scholar 

  11. Toner GC, Bosl GJ (1990) Sarcoidosis, „Sarcoid-like lymphadenopathy,“ and testicular germ cell tumors. Am J Med 89(5): 651–656

    Article  PubMed  Google Scholar 

  12. Venissac N, Alifano M, Mouroux J (2003) Video-assisted mediastinoscopy: experience from 240 consecutive cases. Ann Thorac Surg 76(1): 208–212

    Article  PubMed  Google Scholar 

Download references

Interessenkonflikt

Es besteht kein Interessenkonflikt. Der korrespondierende Autor versichert, dass keine Verbindungen mit einer Firma, deren Produkt in dem Artikel genannt ist, oder einer Firma, die ein Konkurrenzprodukt vertreibt, bestehen. Die Präsentation des Themas ist unabhängig und die Darstellung der Inhalte produktneutral.

Author information

Authors and Affiliations

  1. Urologische Klinik, Carl-Thiem-Klinikum, Akademisches Lehrkrankenhaus der Universitätsklinik Charité zu Berlin, Thiemstraße 111, 03048, Cottbus

    M. May, C. Helke & B. Hoschke

  2. Pathologisches Institut, Carl-Thiem-Klinikum, Cottbus

    S. Gunia & O. Kaufmann

  3. Urologische Klinik, Vivantes-Klinikum Am Urban, Berlin

    M. Siegsmund

  4. Urologische Universitätsklinik, Charité, Campus Mitte, Berlin

    A. H. Wille

Authors
  1. M. May
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. S. Gunia
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. M. Siegsmund
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. O. Kaufmann
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. C. Helke
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. B. Hoschke
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. A. H. Wille
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to M. May.

Rights and permissions

Reprints and permissions

About this article

Cite this article

May, M., Gunia, S., Siegsmund, M. et al. Testikulärer Keimzelltumor und Sarkoidose. Urologe 45, 1176–1180 (2006). https://doi.org/10.1007/s00120-006-1052-4

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00120-006-1052-4

Schlüsselwörter

Keywords

Search

Navigation