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Versorgung der erektilen Dysfunktion nach radikaler Prostatektomie in Deutschland

Einschätzung durch den Urologen vs. Patientenbefragung

Management of erectile dysfunction after radical prostatectomy

Urologists’ assessment vs patient survey responses

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Zusammenfassung

Einleitung

Nach radikaler Prostatovesikulektomie (RPX) besteht in Abhängigkeit von der Operationstechnik bei einem Großteil der Patienten eine erektile Dysfunktion (ED), die meist auch zum Therapiewunsch führt. Ziel dieser nationalen Studie war es, die ED-Versorgung nach RPX (ohne postoperative adjuvante Therapie und ohne Rezidiv) aus Patienten- und Urologensicht gegenüberzustellen.

Material und Methoden

Im Mai 2003 wurden 1063 in Deutschland niedergelassene Urologen und 801 rezidivfreie Patienten nach RPX ohne adjuvante Therapie angeschrieben. Gefragt wurde nach erhaltener Potenz nach RPX ohne Hilfsmittel, vorhandenem Therapiewunsch, empfohlenen bzw. getesteten Therapiemöglichkeiten (oral, transurethral, Schwellkörperautoinjektionstherapie (SKAT), Vakuumerektionshilfe, Schwellkörperimplantat) sowie der langfristigen Versorgung (Rücklauf: Patienten 80%, Urologen 27%).

Ergebnisse

Ohne Hilfsmittel postoperativ GV-fähig sind nach Urologenangaben 9,1% ihrer betroffenen Patienten, jedoch nur 4,7% der befragten Betroffenen. Ein Therapiewunsch wird nach Aussage der Urologen von 46,1% ihrer Patienten geäußert, wohingegen 44,8% bei ED keinen Therapiewunsch angeben. Nach Patientenaussage wünschen 59,3% eine Therapie, nur 28,5% wollen keine Versorgung in Anspruch nehmen. Während die Urologen schätzen, dass bei 26,1% ihrer betroffenen Patienten mit Therapiewunsch langfristig keine ED-Behandlung erfolgt, sind dies nach Patientenaussage 69,7%. Nur 30,3% der Patienten nehmen nach eigenen Aussagen langfristig eine ED-Therapie wahr, während die Urologen diesen Anteil auf 73,9% schätzen. Die ED-Einstellung erfolgt nach Urologenschätzungen langfristig: oral 38,4%, MUSE® 3,6%, SKAT 37,3%, Vakuumerektionshilfe 20,4%, Schwellkörperimplantat 0,3%. Die Betroffenen selbst verwenden dagegen langfristig nachstehende Mittel: oral 19,8%, MUSE® 1,7%, SKAT 26,7%, Vakuumerektionshilfe 50,9%, Schwellkörperimplantat 0,9%. Die Urologen schätzen die Therapiezufriedenheit ihrer Patienten durchschnittlich auf 46,2%, dagegen liegt die tatsächliche Rate bei den Patienten bei 28,9%.

Schlussfolgerungen

Die Gegenüberstellung der Patienten- und Urologenaussagen zeigt eine deutlich unterschiedliche Einschätzung der ED-Situation nach RPX. Der Anteil der Patienten mit Therapiewunsch und der Anteil, der mit der Behandlung unzufriedenen Patienten, liegt aus Patientensicht deutlich höher. Dies reflektiert eine Unterversorgung der ED-Patienten nach RPX, der auch unter den aktuellen Veränderungen des Gesundheitssystems in Deutschland Rechnung zu tragen ist.

Abstract

Introduction

After radical prostatectomy (RPX) a majority of patients suffer from erectile dysfunction (ED). Most of them wish to be treated. The aim of this national study was to evaluate ED management after RPX (without any postoperative adjuvant therapy or tumor relapse) from the patient’s view compared to the urologist’s view.

Material and methods

In May 2003 we queried 1063 urologists and 801 patients following radical prostatectomy without adjuvant therapy. They were asked about preserved potency after RPX without erectile aid, existing wish for ED therapy, recommended or tested erectile aid (oral, transurethral, intracorporal, vacuum constriction device, penile implant) as well as the long-term use. Return rate: patients 80.1%, urologists 26.7%.

Results

According to the urologists’ view 9.1% of their affected patients were potent postoperatively without a device, but according to the polled patients only 4.7%. The wish to be treated for erectile dysfunction existed in the urologists’ opinion in 46.1% of their patients, while they considered that 44.8% had no wish for treatment. On the other hand, 59.3% of the patients would like to be treatedand only 28.5% did not want any kind of treatment. Regarding the long-term use of therapy for ED, the urologists thought that 26.1% of their patients did not receive therapy for the problem, and 69.7% of the patients stated they received no long-term therapy. Only 30.3% of the patients confirmed long-term therapy, while the urologists thought that 73.9% of the patients used an erectile aid. Definite therapy in the urologists’ opinion involved oral medication in 38.4%, MUSE® in 3.6%, Schwellkörperautoinjektionstherapie (SKAT) in 37.3%, erectile aid systems in 20.4%, and a prosthesis in 0.3%. Indeed 19.8% of the patients used oral medication, 1.7% MUSE®, 26.7% SKAT, 50.9% a vacuum constriction device, and 0.9% a penile implant. Considering the satisfaction of patients, urologists thought that 46.2% of the patients were satisfied with their treatment of ED, but only 28.9% of the patients were actually satisfied themselves.

Conclusions

The comparison of patients’ and urologists’ views shows a clearly different description of the ED situation after RPX. The proportion of patients with a wish for treatment and the proportion of dissatisfied patients are much higher from the patients’ view. This demonstrates an undertreatment of ED patients after RPX, which should also be taken into account under the current changes in the German health care system.

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Literatur

  1. Bertz J, Hentschel S, Hundsdörfer G et al. (2004) Prostata. In: Arbeitsgemeinschaft Bevölkerungsbezogener Krebsregister in Deutschland (Hrsg) Krebs in Deutschland — Häufigkeiten und Trends, 4. Aufl. Arbeitsgemeinschaft Bevölkerungsbezogener Krebsregister in Deutschland, Saarbrücken, S 64–67

  2. Jemal A, Thomas A, Murray T, Thun M (2002) Cancer statistics, 2002. CA Cancer J Clin 52: 23–47

    PubMed  Google Scholar 

  3. Catalona WJ, Smith DS, Ratliff TL, Basler JW (1993) Detection of organ-confined prostate cancer is increased through prostate-specific antigen-based screening. J Am Med Assoc 270: 948–954

    Article  Google Scholar 

  4. Hankey BF, Feuer EJ, Clegg LX et al. (1999) Cancer surveillance series: interpreting trends in prostate cancer, part I: Evidence of the effects of screening in recent prostate cancer incidence, mortality, and survival rates. J Natl Cancer Inst 91: 1017–1024

    Article  PubMed  Google Scholar 

  5. Kopecky AA, Laskowski TZ, Scott R Jr (1970) Radical retropubic prostatectomy in the treatment of prostatic carcinoma. J Urol 103: 641–644

    PubMed  Google Scholar 

  6. Veenema RJ, Gursel EO, Lattimer JK (1977) Radical retropubic prostatectomy for cancer: a 20-year experience. J Urol 117: 330–331

    PubMed  Google Scholar 

  7. Walsh PC (2000) Radical prostatectomy for localized prostate cancer provides durable cancer control with excellent quality of life: a structured debate. J Urol 163: 1802–1807

    Article  PubMed  Google Scholar 

  8. Walsh PC, Marschke P, Ricker D, Burnett AL (2000) Patient-reported urinary continence and sexual function after anatomic radical prostatectomy. Urology 55: 58–61

    Article  Google Scholar 

  9. Zippe CD, Raina R, Thukral M, Lakin MM, Klein EA, Agarwal A (2001) Management of erectile dysfunction following radical prostatectomy. Curr Urol Rep 2: 495–503

    PubMed  Google Scholar 

  10. Boccon-Gibod L, Djavan WB, Hammerer P et al. (2004) Management of prostate-specific antigen relapse in prostate cancer: a European Consensus. Int J Clin Pract 58: 382–390

    Article  PubMed  Google Scholar 

  11. Klein LT, Miller MI, Buttyan R et al. (1997) Apoptosis in the rat penis after penile denervation. J Urol 158: 626–630

    Article  PubMed  Google Scholar 

  12. Leungwattanakij S, Bivalacqua TJ, Usta MF et al. (2003) Cavernous neurotomy causes hypoxia and fibrosis in rat corpus cavernosum. J Androl 24: 239–245

    PubMed  Google Scholar 

  13. Moreland RB (1998) Is there a role of hypoxemia in penile fibrosis: a viewpoint presented to the Society for the Study of Impotence. Int J Impot Res 10: 113–120

    Article  PubMed  Google Scholar 

  14. Mulhall JP, Slovick R, Hotaling J, Aviv N, Valenzuela R, Waters WB, Flanigan RC (2002) Erectile dysfunction after radical prostatectomy: hemodynamic profiles and their correlation with the recovery of erectile function. J Urol 167: 1371–1375

    Article  PubMed  Google Scholar 

  15. Yao KS, Clayton M, O’Dwyer PJ (1995) Apoptosis in human adenocarcinoma HT29 cells induced by exposure to hypoxia. J Natl Cancer Inst 87: 117–122

    PubMed  Google Scholar 

  16. Chen J, Mabjeesh NJ, Greenstein A (2001) Sildenafil versus the vacuum erection device: patient preference. J Urol 166: 1779–1781

    Article  PubMed  Google Scholar 

  17. Lewis RW, Witherington R (1997) External vacuum therapy for erectile dysfunction: use and results. World J Urol 15: 78–82

    Article  PubMed  Google Scholar 

  18. Claro JD, Aboim JE, Maringolo M et al. (2001) Intracavernous injection in the treatment of erectile dysfunction after radical prostatectomy: an observational study. Sao Paulo Med J 119: 135–137

    Article  PubMed  Google Scholar 

  19. Raina R, Lakin MM, Thukral M et al. (2003) Long-term efficacy and compliance of intracorporeal (IC) injection for erectile dysfunction following radical prostatectomy: SHIM (IIEF-5) analysis. Int J Impot Res 15: 318–322

    Article  PubMed  Google Scholar 

  20. Mulhall JP, Jahoda AE, Cairney M et al. (1999) The causes of patient dropout from penile self-injection therapy for impotence. J Urol 162: 1291–1294

    Article  PubMed  Google Scholar 

  21. Purvis K, Egdetveit I, Christiansen E (1999) Intracavernosal therapy for erectile failure — impact of treatment and reasons for drop-out and dissatisfaction. Int J Impot Res 11: 287–299

    Article  PubMed  Google Scholar 

  22. Chung D, Hersey K, Fleshner N (2005) Differences between urologists in United States and Canada in approach to bladder cancer. Urology 65: 919–25

    Article  PubMed  Google Scholar 

  23. Noldus J, Michl U, Graefen M, Haese A, Hammerer P, Huland H (2002) Patient-reported sexual function after nerve-sparing radical retropubic prostatectomy. Eur Urol 42: 118–124

    Article  PubMed  Google Scholar 

  24. Aus G, Abbou CC, Pacik D, Schmid HP, van Poppel H, Wolff JM, Zattonie F (2001) EAU guidelines on prostate cancer. Eur Urol 40: 97–101

    Article  PubMed  Google Scholar 

  25. Montorsi F, Briganti A, Salonia A, Rigatti P, Burnett AL (2004) Current and future strategies for preventing and managing erectile dysfunction following radical prostatectomy. Eur Urol 45: 123–133

    Article  PubMed  Google Scholar 

  26. Cookson MS, Nadig PW (1993) Long-term results with vacuum constriction device. J Urol 149: 290–294

    PubMed  Google Scholar 

  27. Denil J, Ohl DA, Smythe C (1996) Vacuum erection device in spinal cord injured men: patient and partner satisfaction. Arch Phys Med Rehabil 77: 750–753

    Article  PubMed  Google Scholar 

  28. Nunez Mora C, Rios Gonzalez E, Martinez-Pineiro L et al. (2000) Treatment of erectile dysfunction with vacuum devices. Arch Esp Urol 53: 819–825

    PubMed  Google Scholar 

  29. Vives Sune A, Ribe Subira N, Manasia P, Pomerol Monseny JM (2000) Patient response to and assessment of intracavernous drug injection and vacuum. Actas Urol Esp 24: 231–234

    PubMed  Google Scholar 

  30. McCullough AR (2001) Prevention and management of erectile dysfunction following radical prostatectomy. Urol Clin North Am 28: 613–627

    Article  PubMed  Google Scholar 

  31. Soderdahl DW, Thrasher JB, Hansberry KL (1997) Intracavernosal drug-induced erection therapy versus external vacuum devices in the treatment of erectile dysfunction. Br J Urol 79: 952–957

    PubMed  Google Scholar 

  32. Rösing D, Berberich HJ (2004) Krankheits- und behandlungsbedingte Sexualstörungen nach radikaler Prostatektomie. Urologe A 43: 291–295

    Article  PubMed  Google Scholar 

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Herkommer, K., Niespodziany, S., Zorn, C. et al. Versorgung der erektilen Dysfunktion nach radikaler Prostatektomie in Deutschland. Urologe 45, 336–342 (2006). https://doi.org/10.1007/s00120-005-0972-8

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