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SPECT/CT-Infektdiagnostik am Skelett

SPECT/CT diagnostics for skeletal infections

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Zusammenfassung

Klinisches/methodisches Problem

Knöcherne Infekte stellen nicht selten eine diagnostische und klinische Herausforderung dar.

Radiologische Standardverfahren

Nuklearmedizinische Standardverfahren für die Diagnostik akuter und chronischer Knocheninfekte sind die Mehrphasenskelettszintigraphie und die Infektszintigraphie mit markierten Leukozyten.

Methodische Innovationen

Die Einführung von Hybridtechnologien wie der SPECT/CT hat die nuklearmedizinische Infektbildgebung tiefgreifend verändert.

Leistungsfähigkeit

Die SPECT/CT erlaubt bei der Frage nach Knocheninfekten insgesamt eine wesentlich genauere Beurteilung als planare Aufnahmen und SPECT.

Bewertung

Die integrierte Akquisition von metabolischer, funktioneller und topographisch-morphologischer Information mit SPECT/CT steigerte insbesondere die Spezifität der Mehrphasenskelettszintigraphie und der Infektszintigraphie mit markierten Leukozyten.

Abstract

Clinical/methodical issue

Skeletal infections are often a diagnostic and clinical challenge.

Standard radiological methods

Nuclear imaging modalities used in the diagnostic workup of acute and chronic skeletal infections include three-phase bone scintigraphy and scintigraphy with labelled leucocytes.

Methodical innovations

The introduction of hybrid technologies, such as single photon emission computed tomography/computed tomography (SPECT/CT) has dramatically changed nuclear medical imaging of infections.

Performance

In general SPECT/CT leads to a considerably more accurate diagnosis than planar or SPECT imaging.

Achievements

Given the integrated acquisition of metabolic, functional and morphological information, SPECT/CT has increased in particular the specificity of three-phase skeletal scanning and scintigraphy with labeled leucocytes.

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Interessenkonflikt

Der korrespondierende Autor weist auf folgende Beziehung hin: Dr. Klaeser hat Honorare für Vorträge von der Firma Philips AG Healthcare erhalten.

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Authors and Affiliations

  1. Universitätsklinik für Nuklearmedizin, Inselspital Bern, Freiburgstr. 10, CH-3010, Bern, Schweiz

    B. Klaeser, M. Spanjol & T. Krause

Authors
  1. B. Klaeser
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  2. M. Spanjol
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  3. T. Krause
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Corresponding author

Correspondence to B. Klaeser.

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Klaeser, B., Spanjol, M. & Krause, T. SPECT/CT-Infektdiagnostik am Skelett. Radiologe 52, 615–620 (2012). https://doi.org/10.1007/s00117-011-2272-1

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