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Schlängelung und Verkalkung der Milzarterie im Röntgenbild

Mehr als ein Nebenbefund

Tortuosity and calcification of the splenic artery

More than an additional finding

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Zusammenfassung

Die Schlängelung der Milzarterie und Verkalkungen in der Wand des Gefäßes sind ein typischer Nebenbefund bei der Röntgenuntersuchung des Abdomens. Die Kombination wird v. a. bei Senioren beobachtet, ohne dass Symptome einer Mangelperfusion der Milz fassbar sind. Bei der Pathogenese wirken eine Reihe verschiedener Faktoren zusammen. Im Kindesalter verläuft die A. lienalis stets gestreckt. Die zunehmende Schlängelung wird durch die wachsende Differenz zwischen der Länge des Gefäßes und der Distanz zwischen seinem Ursprung und dem Milzhilus hervorgerufen. Der proximale Abschnitt der Arterie ist häufiger und stärker betroffen als der distale. Die Tortuositas wird durch die zum Hauptstamm senkrechte Verlaufsrichtung der großen Äste gefördert. Weder die Schlängelung noch die Verkalkung sind als Risikoindikatoren für das vergleichsweise häufige Aneurysma der Milzarterie zu werten. Der Wandkalk ist sowohl in der Tunica media wie im Endothel lokalisiert. Hämodynamisch wirksame kalkassoziierte Gefäßstenosen fehlen. Die verkalkende Atheromatose der Milzarterie ähnelt der Mediasklerose der peripheren Arterien vom Typ Mönckeberg und wird bei Diabetikern und Dialysepatienten überdurchschnittlich häufig nachgewiesen. Die hydrohämodynamische Theorie der Arteriosklerose kann nur für die quantitativ weniger bedeutsame Verkalkung der Intima verantwortlich gemacht werden. Die Blutspeicherfunktion der Milz fördert die charakteristische altersabhängige Form- und Verlaufsveränderung der A. lienalis.

Abstract

Tortuosity of the splenic artery and calcification of the vessel wall are typical additional findings on plain abdominal x-ray. The combination of both anomalies is common in elderly persons presenting without symptoms of splenic ischemia. Its pathogenesis is thought to be multifactorial. In infancy and childhood, the splenic artery is stretched in its entire course. A growing difference between the length of the vessel and the distance between its origin and the splenic hilum gives rise to tortuosity. The artery’s proximal segment is involved more frequently and more severely than the distal one. The tortuous route of the vessel is accentuated by the direction of its major branches, which is roughly perpendicular to the main trajectory. Neither tortuosity nor calcification should be taken to be risk factors for the comparatively common splenic artery aneurysm. Calcific deposits are not confined to the media but are also detected in the intima of the vascular wall. Critical narrowings of the lumen arising on the calcium deposits are not observed. Calcifying atherosclerosis of the splenic artery is comparable to medial sclerosis of the peripheral arteries frequently noticed in diabetics and dialysis patients. Only the less important calcification of the intima may be attributed to mechanisms of the hydrohemodynamic theory of atherosclerosis. The spleen’s blood storage capacity may contribute to the characteristic age-dependent alterations of the shape and course of the splenic artery.

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Literatur

  1. Abbas MA, Stone WM, Fowl RJ et al. (2002) Splenic artery aneurysms: two decades experience at Mayo Clinic. Ann Vasc Surg 16: 442–449

    Article  PubMed  Google Scholar 

  2. Baron MG (1994) Significance of coronary artery calcification. Radiology 192: 613–614

    PubMed  CAS  Google Scholar 

  3. Bedford PD, Lodge B (1960) Aneurysm of the splenic artery. Gut 1: 312–320

    Article  PubMed  CAS  Google Scholar 

  4. Borley NR, McFarlane JM, Ellis H (1995) A comparative study of the tortuosity of the splenic artery. Clin Anat 8: 219–221

    Article  PubMed  CAS  Google Scholar 

  5. Childress MH, Cho KJ, Newlin N, Martel W (1979) Arterial impressions on the stomach. AJR 132: 769–772

    PubMed  CAS  Google Scholar 

  6. Cornhill JF, Atkins D, Hutson M, Chandler AB (1980) Localisation of atherosclerotic lesions in the human basilar artery. Atherosclerosis 35: 77–86

    Article  PubMed  CAS  Google Scholar 

  7. Daisy Sahni A, Indar Jit B, Gupta CN et al. (2003) Branches of the splenic artery and splenic arterial segments. Clin Anat 16: 371–377

    Article  Google Scholar 

  8. De Schepper AM, Vanoenacker F, OP de Beeck B, Gielen J, Parizel P (2005) Vascular pathology of the spleen, part I. Abdom Imaging 30: 96–104

    Google Scholar 

  9. Dietrich K (1930) Beiträge zur Pathologie der Arterien des Menschen. Virchows Arch Path Anat 274: 452–527

    Article  Google Scholar 

  10. Ekelund L, Gerlock J, Molin J, Smith C (1978) Roentgenologic appearance of fibromuscular dysplasia. Acta Radiol Diagn (Stockh) 19: 433–446

    Google Scholar 

  11. Feigl W, Sinzinger H, Wagner O, Leithner Ch (1975) Quantitative morphological investigations on smooth muscle cells in vascular surgical specimens and their clinical importance. Experientia 31: 1352–1353

    Article  PubMed  CAS  Google Scholar 

  12. Feigl W, Sinzinger H, Howanietz J, Leithner C (1976) A morphological different type of smooth muscle cell in the inner media of the splenic artery. Acta Anat 94: 617–625

    Article  PubMed  CAS  Google Scholar 

  13. Feist JH, Gajaraj A (1977) Extra- and intrasplenic artery aneurysms in portal hypertension. Radiology 125: 331–334

    PubMed  CAS  Google Scholar 

  14. Frippiat F, Donckier J, Vandenbossche P et al. (1996) Splenic infarction: report of three cases of atherosclerotic embolization originating in the aorta and retrospective study of 64 cases. Acta Clin Belg 51: 395–402

    PubMed  CAS  Google Scholar 

  15. Hong Z, Chen F, Yang J, Wu Z, Yan Z (1999) Diagnosis and treatment of splanchnic artery aneurysms: a report of 57 cases. Chin Med J (Engl) 112: 29–33

    Google Scholar 

  16. Jauregui E (1999) Anatomy of the splenic artery. Rev Fac Cien Med Univ Nac Cordoba 56: 21–41

    PubMed  CAS  Google Scholar 

  17. Javors BR (1999) Tortuosity of the splenic artery. Abdom Imaging 24: 313–314

    Article  PubMed  CAS  Google Scholar 

  18. Kunz R (1980) Aneurysmata bei 35380 Autopsien. Schweiz Med Wochenschr 110:142–148

    PubMed  CAS  Google Scholar 

  19. Levin MF, Vellet AD, Bach DB et al. (1992) Peripancreatic fluid collections: vascular structures masquerading as pseudocysts. Can Assoc Radiol J 43: 267–272

    PubMed  CAS  Google Scholar 

  20. Majeski J (1998) Splenic artery tortuosity simulating a splenic artery aneurysm. South Med J 91: 949–951

    PubMed  CAS  Google Scholar 

  21. Meyer WW, Henschel E (1968) Untersuchungen über die Schlängelung und Sklerose der Milzarterie. Virch Arch Anat Path 331: 396–416

    Article  Google Scholar 

  22. Meyer WW, Stelzig HH (1968) Morphologie des Spaltensystems der inneren elastischen Membran muskulärer Arterien. Z Zellforsch 88: 415–425

    Article  Google Scholar 

  23. Meyer WW, Weber G (1968) Calcinose und Spaltensystem der inneren elastischen Membran der geschlängelten Milzarterien. Virch Arch Abt A Path Anat 345: 292–298

    Article  CAS  Google Scholar 

  24. Michels NA (1955) The spleen, the splenic artery and the intrasplenic circulation. In: Blood supply and anatomy of the upper abdominal organs. Lippincott, Philadelphia, pp 220–235

  25. Okuda K, Kobayashi S, Hayashi H et al. (2002) Case-control study of calcification of the hepatic artery in chronic hemodialysis patients: Comparison with the abdominal aorta and splenic artery. J Gastroenterol Hepatol 17: 91–95

    Article  PubMed  Google Scholar 

  26. Oran I, Yesildag A, Memis A (2001) Aortic origin of right hepatic artery and superior mesenteric origin of splenic artery: two rare variations demonstrated angiographically. Surg Radiol Anat 23: 349–352

    Article  PubMed  CAS  Google Scholar 

  27. Orr DP, Myerowitz RL, Herbert DL, Friday P (1978) Correlation of radiographic and histologic findings in arterial calcification. Invest Radiol 13: 110–114

    Article  PubMed  CAS  Google Scholar 

  28. Ozan H, Onderoglu S (1997) Intrapancreatic course of the splenic artery with combined pancreatic anomalies. Surg Radiol Anat 19: 409–411

    Article  PubMed  CAS  Google Scholar 

  29. Palubinskas AJ, Ripley HR (1984) Fibromuscular hyperplasia in extrarenal arteries. Radiology 82: 451–455

    Google Scholar 

  30. Pandey SK, Bhattacharya S, Mishra RN, Shukla VK (2004) Anatomical variations of the splenic artery and its clinical implications. Clin Anat 17: 497–502

    Article  PubMed  CAS  Google Scholar 

  31. Partanen K, Soimakallio S, Kivimaki T et al. (1984) Dynamic topography of the contrast enhancement of the spleen. Eur J Radiol 4: 101–106

    PubMed  CAS  Google Scholar 

  32. Sinzinger H, Silberbauer K, Winter M (1979) Diminished prostacyclin generation by human atherosclerotic lesions. Lancet I: 803–804

    Google Scholar 

  33. Sinzinger H, Firbas W (1985) Pathology of the splenic artery. Experientia 41: 224–232

    Article  PubMed  CAS  Google Scholar 

  34. Smythe CM, Gibson DB (1963) Upper-quadrant bruit due to tortuous splenic artery. N Engl J Med 269: 1308–1309

    Article  PubMed  CAS  Google Scholar 

  35. Sylvester PA, Stewart R, Ellis H (1995) Tortuosity of the human splenic artery. Clin Anat 8: 214–218

    Article  PubMed  CAS  Google Scholar 

  36. Texon M (1960) The hemodynamic concept of atherosclerosis. Bull NY Acad Med 36: 236–274

    Google Scholar 

  37. Texon M, Imparato AM, Lord JW Jr, Helpern M (1962) Experimental production of arterial lesions. Arch Intern Med 110: 50–52

    PubMed  CAS  Google Scholar 

  38. Texon M, Imparato AM, Helpern M (1965) The role of vascular dynamics in the development of atherosclerosis. JAMA 194: 168–172

    Article  Google Scholar 

  39. Thiersch H (1935) Beitrag zur Pathologie der Arteria lienalis. Beitr Path Anat 96: 174–176

    Google Scholar 

  40. Tischendorf F (1970) Zum Problem der Milzarterie. Z Anat Entw Gesch 132: 339–349

    Article  CAS  Google Scholar 

  41. Vanhoenacker FM, Op de Beeck B, De Schepper AM et al. (2007) Vascular disease of the spleen. Semin Ultrasound CT MR 28: 35–51

    Article  PubMed  CAS  Google Scholar 

  42. Wood NB, Zhao SZ, Zambanini A et al. (2006) Curvature and tortuosity of the superficial femoral artery: a possible risk factor for peripheral arterial disease. J Appl Physiol 101: 1412–1418

    Article  PubMed  CAS  Google Scholar 

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Golder, W. Schlängelung und Verkalkung der Milzarterie im Röntgenbild. Radiologe 48, 1066–1074 (2008). https://doi.org/10.1007/s00117-008-1631-z

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