Zusammenfassung
Die Zwangsstörung ist eine schwere und massiv beeinträchtigende psychische Erkrankung, die ohne adäquate Behandlung in der Regel chronisch verläuft. Kognitive Verhaltenstherapie mit Exposition stellt zum heutigen Zeitpunkt das am besten untersuchte und nach wissenschaftlichen Kriterien wirksamste Verfahren bei Zwängen dar. 60–70% der Patienten können hiermit zu einer klinisch bedeutsamen Verbesserung ihrer Symptome gelangen. Richtig angewandt, ist Expositionsbehandlung in vielen Fällen vergleichbar wirksam wie deren Kombination mit medikamentöser Behandlung und kennt nur wenige Kontraindikationen. Allerdings sind für die korrekte Durchführung einige Punkte zu beachten, die in dem folgenden Beitrag näher erläutert werden. Da ein Teil der Patienten von dem Behandlungsansatz dennoch nicht hinreichend profitiert, werden auch mögliche Alternativen und Erweiterungen des Expositionsansatzes vorgestellt. Bislang stehen Nachweise für deren Wirksamkeit über randomisierte, kontrollierte Studien jedoch noch aus.
Summary
Obsessive-compulsive disorder is a severe, very disabling condition that usually takes a chronic course if no adequate treatment is applied. Up to now, cognitive behavioural therapy with exposure and response prevention (CBT) is the most thoroughly investigated and most effective intervention, leading to a clinically significant symptom reduction in 60–70% of the patients. Correctly applied, this treatment can be equally effective as its combination with pharmacological management. For a correct implementation, however, several points have to be considered which are described in the following review. Considering the fact that some of the patients are unable to benefit sufficiently from this approach, potential alternatives and extensions of CBT are discussed. To date, however, no other treatment approach has proven to be effective based on randomised controlled trials.
Literatur
Gava I, Barbui C, Aguglia E et al (2007) Psychological treatments versus treatment as usual for obsessive compulsive disorder (OCD). Cochrane Database Syst Rev Issue 2
Rosa-Alcázar AI, Sánchez-Meca J, Gómez-Conesa A, Marín-Martíne F (2008) Psychological treatment of obsessive – compulsive disorder: a meta-analysis. Clin Psychol Rev 28(8):1310–1325
Koran LM, Hanna GL, Hollander E et al (2007) American Psychiatric Association. Practice guideline for the treatment of patients with obsessive-compulsive disorder. Am J Psychiatry 164(7):5–53
Hohagen F, Winkelmann G, Rasche-Räuchle H et al (1998) Combination of behaviour therapy with fluvoxamine in comparison with behaviour therapy and placebo. Results of a multicentre study. Br J Psychiatr (Suppl 35):71–78
Rufer M, Hand I, Alsleben H et al (2005) Long-term course and outcome of obsessive-compulsive patients after cognitive-behavioral therapy in combination with either fluvoxamine or placebo: a 7-year follow-up of a randomized double-blind trial. Eur Arch Psychiatry Clin Neurosci 255(2):121–128
Jonsson H, Hougard E (2009) Group cognitive behavioural therapy for obsessive-compulsive disorder: a systematic review and meta-analysis. Acta Psychiatr Scand 119:98–106
McMillan D, Lee R (2010) A systematic review of behavioral experiments vs exposure alone in the treatment of anxiety disorders: a case of exposure while wearing the emperor’s new clothes? Clin Psychol Rev 30(5):467–478
Abramowitz JS (2006) The psychological treatment of obsessive-compulsive disorder. Can J Psychiatry 51:407–416
Grawe K, Gassmann D (2006) General change mechanisms: the relation between problem activation and resource activation in successful and unsuccessful therapeutic interactions. Clin Psychol Psychother 13(1):1–11
Salkovskis PM (2007) Obsessive-compulsive disorder is uncommon but associated with high levels of comorbid neuroses, impaired function and increased suicidal acts in people in the UK. Evid Based Ment Health (3):93
Marques L, LeBlanc NJ, Weingarden HM et al (2010) Barriers to treatment and service utilization in an internet sample of individuals with obsessive-compulsive symptoms. Depress Anxiety 27(5):470–475
Külz AK, Hassenpflug K, Riemann D et al (2009) Ambulante psychotherapeutische Versorgung bei Zwangserkrankungen. Ergebnisse einer anonymen Therapeutenbefragung. Psychother Psychosom Med 59:1–8
Oppen P van, Balkom AJ van, Smit JH et al (2010) Does the therapy manual or the therapist matter most in treatment of obsessive-compulsive disorder? A randomized controlled trial of exposure with response or ritual prevention in 118 patients. J Clin Psychiatry 71(9):1158–1167
Pence SL Jr, Sulkowski ML, Jordan C, Storch EA (2010) When exposures go wrong: troubleshooting guidelines for managing difficult scenarios that arise in exposure-based treatment for obsessive-compulsive disorder. Am J Psychother 64(1):39–53
Simpson HB, Maher M, Page JR et al (2010) Development of a patient adherence scale for exposure and response prevention therapy. Behav Ther 41(1):30–37
Külz AK, Lumpp A, Herbst N et al (2010) Welche Funktionen erfüllen Zwangsstörungen? Ergebnisse einer deskriptiven Erhebung an stationären Patienten. Verhaltenstherapie 20:101–108
Hand I (2008) Strategisch-systemische Aspekte der Verhaltenstherapie. Springer, Wien
Maher MJ, Huppert JD, Chen H et al (2010) Moderators and predictors of response to cognitive-behavioral therapy augmentation of pharmacotherapy in obsessive-compulsive disorder. Psychol Med 26:1–11
Shavitt RG, Valério C, Fossaluza V et al (2010) The impact of trauma and post-traumatic stress disorder on the treatment response of patients with obsessive-compulsive disorder. Eur Arch Psychiatry Clin Neurosci 260(2):91–99
Steketee G, Frost RO, Tolin DF et al (2010) Waitlist controlled trial of cognitive behaviour therapy for hoarding disorder. Depress Anxiety 27:476–484
Belloch A, Cabedo E, Carrió C, Larsson C (2010) Cognitive therapy for autogenous and reactive obsessions: clinical and cognitive outcomes at post-treatment and 1-year follow-up. J Anxiety Disord 24(6):573–580
Twohig MP, Hayes SC, Plumb JC et al (2010) A randomized clinical trial of acceptance and commitment therapy versus progressive relaxation training for obsessive-compulsive disorder. J Consult Clin Psychol 78:705–716
Moritz S (2010) Erfolgreich gegen Zwangsstörungen: Metakognitives Training – Denkfallen erkennen und entschärfen. Springer, Heidelberg
Rees CS, Koesveld KE van (2008) An open trial of group metacognitive therapy for obsessive-compulsive disorder. J Behav Ther Exp Psychiatry 39(4):451–458
Gorbis E, Molnar C, O’Neill J et al (2007) Mindfulness-based behavioral therapy (MBBT) for severe obsessive compulsive disorder improves therapy outcome for people who were previously unresponsive to traditional interventions. Abstract presented at the 5th annual conference of the Center for Mindfulness in Medicine, Healthcare, and Society, Worcester, MA, March 28–April 1, 2007
Voderholzer U, Hohagen FC (2010) Therapie psychischer Erkrankungen. State of the art. Elsevier, München
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Külz, A., Voderholzer, U. Psychotherapie der Zwangsstörung. Nervenarzt 82, 308–318 (2011). https://doi.org/10.1007/s00115-010-2962-3
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DOI: https://doi.org/10.1007/s00115-010-2962-3