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Inhibition of lipid peroxidation by extracts/subfractions of Chickrassy (Chukrasia tabularis A. Juss.)

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Abstract

Polyphenols and polyphenol-rich fractions of plants have been reported to have protective effects against lipid peroxidation, most probably by serving as scavengers of free radicals and/or by chelating metal ions. In the present study, the effect of different extracts/subfractions of Chickrassy (Chukrasia tabularis) on peroxyl radical mediated damage to the polyunsaturated fatty acids was investigated. Liver homogenate was used as experimental material. The production of malondialdehyde served as a marker of lipid peroxidation and oxidative stress. It was observed that polyphenol-rich fractions, particularly the ethyl acetate fractions of bark and leaves, showed the highest protective activity of 83.02% and 88.62% inhibition, respectively. This study will help in knowing the scientific validation of this plant, for its use in ayurvedic formulations.

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Acknowledgment

This work is supported by the Fellowship from University Grants Commission, New Delhi. Dr. P.S. Ahuja, Director, Institute of Himalayan Bioresource Technology (IHBT) Palampur (HP) is duly acknowledged for providing necessary lab facilities to pursue the work on fractionation of the active extracts.

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Authors and Affiliations

  1. Department of Botanical and Environmental Sciences, Guru Nanak Dev University, Amritsar-143005, Punjab, India

    Rajbir Kaur, Tarunpreet Singh Thind & Saroj Arora

  2. Natural Plant Product Division, Institute of Himalayan Bioresource Technology (IHBT), Palampur, P.O. Box 6-176061, Himachal Pradesh, India

    Bikram Singh

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  1. Rajbir Kaur
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  2. Tarunpreet Singh Thind
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  3. Bikram Singh
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  4. Saroj Arora
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Corresponding author

Correspondence to Saroj Arora.

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The current in vitro experiments performed herewith comply with the current laws of India.

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Kaur, R., Thind, T.S., Singh, B. et al. Inhibition of lipid peroxidation by extracts/subfractions of Chickrassy (Chukrasia tabularis A. Juss.). Naturwissenschaften 96, 129–133 (2009). https://doi.org/10.1007/s00114-008-0443-3

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  • DOI: https://doi.org/10.1007/s00114-008-0443-3

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