Zusammenfassung
Hintergrund
Die Verwendung von maschinellen Impulskompressionssystemen zur Thromboseprophylaxe und Schwellungsverminderung stellen zunehmend akzeptierte Methoden dar. Damit möglichst viele Patienten von diesem System profitieren, ist ein effizienter und zeitökonomischer Einsatz notwendig. Die Mindestanwendungsdauer wird mit 2 h täglich angegeben, was aber derzeit noch nicht wissenschaftlich belegt ist.
Patienten und Methoden
Unter Verwendung des A-V-Impulse-Systems™ wurde prospektiv randomisiert an 41 Patienten nach Implantation einer Hüfttotalendoprothese (Hüft-TEP) überprüft, ob mit der Mindestanwendungsdauer ein ausreichender Effekt erzielt werden kann.
Ergebnisse
Postoperativ kam es in der Kontrollgruppe zu 2 Beinvenenthrombosen, während die Impulskompressionsgruppe thrombosefrei blieb. Keine Unterschiede zeigten sich im Ober- und Unterschenkelumfang, auch nicht in der Schmerzanalogskala nach schmerzbedingtem Abbruch zweier Impulskompressionspatienten.
Schlussfolgerung
Das Ergebnis dieser Pilotstudie legt nahe, dass bereits ein sehr kurzer, aber gezielter Einsatz einer maschinellen Impulskompression die Thromboseneigung reduzieren kann. Zur Erstellung von endgültigen Entscheidungsrichtlinien wäre die Überprüfung durch groß angelegte Studien angezeigt.
Abstract
Background
The use of intermittent compression devices for thrombosis prophylaxis and the reduction of postoperative swelling are widely accepted. The recommended minimum application of 2 h daily has never been statistically verified. Without evidence based data, the benefit of this costly equipment cannot be maximized.
Patients and methods
A randomized clinical trial on 41 patients after total hip replacement was performed. The A-V Impulse System was applied for 2 h a day during the first 5 postoperative days to observe whether this time was sufficiently effective.
Results
In the control group, two deep vein thromboses occurred postoperatively, but there were none in the treatment group. Even though two patients from the treatment group had to be excluded from the study because of severe pain, all other parameters including visual analogue pain scale results and limb circumferences were comparable in both groups.
Conclusion
These preliminary results suggest that pump systems can prevent deep venous thrombosis after hip surgery even when applied for only short intervals over a short period of time. However, large scale confirmatory studies are needed.
Literatur
Bergovist D, Benoni G, Nylander G (1996) Low-molecular-weight heparin (enoxaparin) as prophylaxis against venous thromboembolism after total hip replacement. N Engl J Med 335: 696–700
Bonnaire F, Brandt T, Raedecke J, Bonk (1994) A mechanical dynamic ankle passive motion for physical prevention of thrombosis? Changes in hemodynamics in the lower pressure system with new dynamic splints. Unfallchirurg 97(7): 366–371
Bradley JG, Krugener GH, Jager HJ (1993) The effectiveness of intermittend plantar venous compression in prevention of deep venous thrombosis after total hip arthroplasty. J Arthroplasty 8(1): 57–61
Eisele R, Kinzl L (1998) Prevention of thrombosis with physical therapy in trauma surgery. Possibilities and value of individual measures. Unfallchirurg 101(11): 851
Elias A, Cadene A, Elias M et al. (2004) Extended lower limb venous ultrasound for the diagnosis of proximal and distal vein thrombosis in asymptomatic patients after total hip replacement. Eur J Vasc Endovasc Surg 27(4): 438–444
Elliot CG, Dudney TM, Egger M et al. (1999) Calf thigh sequential pneumatic compression compared with plantar venous pneumatic compression to prevent deep-vein thrombosis after non-lower extremity trauma. J Trauma 47(1): 25–32
Fordyce MJF, Ling RSM (1992) A venous pump reduces thrombosis after total hip replacement. J Bone Joint Surg Br 74: 45–49
Francis CW, Pellegrini VD Jr, Stulberg BN et al. (1990) Prevention of venous thrombosis after total knee arthroplasty. Comparison of antithrombin III with low-dose heparin and dextran. J Bone Joint Surg Am 72: 976–982
Franke J, Schaeper O, Kayser R, Mahlfeld K (2003) Heparin induced thrombocytopenia type II after the use of low-molecular weight heparin. Case report and review of the literature. Unfallchirurg 106(1): 77–81
Gardner AM, Fox RH (1983) The venous pump of the human foot – preliminary report. Bristol Med Chir 98: 109–112
Gardner AMN, Fox RH, Lawrence C et al. (1990) Reduction of post-traumatic swelling and compartment pressure by impulse compression of the foot. J Bone Joint Surg Br 72: 810–815
Gillepsie W, Murray D, Gregg PJ, Warwick D (2000) Risks and benefits of prophylaxis against venous thromboembolism in orthopaedic surgery. J Bone Joint Surg Br 82: 475–479
Guy W (1976) US Clinical global impressions scale. ECDEU assessment manual for psychopharmacology: Dept health, education, and welfare publication (AMD). National Institute of Mental Health, Rockville, Md, pp 76–338
Haas S (1997) Thrombosis in trauma and orthopedic surgery. Prevention, diagnosis, therapy. Unfallchirurg 100(4): 307–319
Haas S (2004) Prevention of thromboembolism in surgery. Unfallchirurg 107(11): 1065–1086
Hainer JW, Barrett JS, Assaid CA et al. (2002) Dosing in heavy-weight/obese patients with the LMWH, tinzaparin: a pharmacodynamic study. Thromb Haemost 87(5): 817–823
Hooker JA, Lachiewicz PF, Kelley SS (1999) Efficacy of prophylaxis against thromboembolism with intermittend pneumatic compression after primary and revision total hip arthroplasty. J Bone Joint Surg Am 81: 690–696
Jasek W (2004) Austria Codex Fachinformation. Österreichischer Apotheker-Verlagsgesellschaft m.b.H., Wien
Johnson PN, Smith KM (2004) Low-molecular-weight heparin use in special populations. Orthopedics 2712: 1245–1248
Kalebo DJ, Whitehouse S (1997) Symptomatic venous thrombembolism after total hip replacement. J Bone Joint Surg Br 79: 780–786
Kirschner P (2004) CPM – continuous passive motion: treatment of injured or operated knee-joints using passive movement. A meta-analysis of current literature. Unfallchirurg 107(4): 328–340
Kuhn B (1997) Heparin-induced thrombocytopenia--a serious complication within the scope of heparin therapy. Follow-up of 7 trauma surgery patients. Unfallchirurg 100(8): 646–51
Lachiewicz PF, Hollemann JB (1995) Aspirin prophylaxis and surveillance of thromboembolism in total hip arthroplasty orthopaedics. Int Edit 5(2): 167–173
Lachiewicz PF, Klein JA, Holleman JB Jr, Kelley S (1996) Pneumatic compression or aspirin prophylaxis against thromboembolism in total hip arthroplasty. J South Orthop Assoc 5(4): 272–280
Lieberman JR, Geerts WH (1994) Prevention of venous thromboembolism after total hip and knee arthroplasty. J Bone Joint Surg Am 76: 1239–1250
Mahlfeld K, Franke J, Schaeper O et al. (2002) Heparin-induced thrombocytopenia as a complication of postoperative prevention of thromboembolism with unfractionated heparin/low molecular weight heparin after hip and knee prosthesis implantation. Unfallchirurg 105(4): 327–31
Mayer A, Hansen M, Peetz D et al. (2003) Prevention of thromboembolism in trauma surgery by dose adjustment of low molecular weight heparin depending on levels of TAT and D-dimer. Unfallchirurg 106(12): 1020–1028
Myerson MS, Henderson MR (1993) Clinical applications of a pneumatic intermittend impulse compression device after trauma and major surgery to the foot and ankle. Foot Ankle 14(4): 198–203
Pietsch M (1997) Mechanische Prophylaxe der tiefen Beinvenenthrombose bei der Totalhüftendoprothese – Experimentelle Strömungsversuche und eine prospektive, randomisierte, klinische Studie. Inauguraldissertation, Medizinische Fakultät, Friedrich-Alexander-Universität, Erlangen-Nürnberg
Planes A, Vochelle N, Darmon JY et al. (1996) Risk of thrombosis after hospital discharge in patients having undergone total hip replacement: double-blind randomised comparison of enoxaparin versus placebo. Lancet 348: 224–228
Ramesh M, Morrissey B, Healy B, Roy-Choudhury S (1999) Effectiveness of the A-V impulse hand pump. J Bone Joint Surg Br 81: 229–233
Robinson KS, Anderson DR, Gross M et al. (1998) Accuracy of screening compression ultrasonography and clinical examination for the diagnosis of deep vein thrombosis after total hip or knee arthroplasty. Can J Surg 41: 368–370
Santori FS, Vitullo A, Stopponi M et al. (1994) Prophylaxis against deep-vein thrombosis in total hip replacement. Comparison of heparin and foot impulse pump. J Bone Joint Surg 76: 579–578
Sarasin FP, Bounameaux H (1996) Antithrombotic strategy after total hip replacement. A cost-effectiveness analysis comparing prolonged oral anticoagulants with screening for deep vein thrombosis. Arch Intern Med 156: 1661–1668
Stannard JP, Harris RM, Bucknell AL et al. (1996) Prophylaxis of deep venous thrombosis after total hip arthroplasty by using intermittend compression of the plantar venous plexus. Am J Orthopedics 2: 127–134
Stöckle U, Hoffmann R, Raschke M et al. (1996) Intermittierende Impulskompression – Die Alternative in der Therapie des posttraumatischen und postoperativen Ödems. Chirurg 67: 539–545
Stranks GJ, MacKenzie NA, Grover ML, Fail T (1992) The A-V Impulse System reduces deep-vein thrombosis and swelling after hemiarthroplasty for hip fracture. J Bone Joint Surg Br 74: 775–778
Stulberg BN, Insall JN, Williams GW, Ghelman B (1984) Deep-vein thrombosis following total knee replacement. An analysis of six hundred and thirty-eight arthroplasties. J Bone Joint Surg Am 66: 194–201
Warwick DJ, Martin A, Glew D (1994) Measurement of femoral vein blood flow during total hip replacement: duplex ultrasound with and without the use of a foot pump. J Bone Joint Surg Br 91: 918–921
Warwick DJ, Whitehouse S (1997) Symptomatic venous thrombembolism after total hip replacement. J Bone Joint Surg Br 79: 780–786
Warwick D, Harrison J, Glew D et al. (1998) Comparison of the use of a foot pump with the use of low-molecular-weight heparin for the prevention of deep-vein thrombosis after total hip replacement. A prospective, randomized trial. J Bone Joint Surg Am 80: 1158–1166
Warwick DJ, Samama MM (2000) The contrast of venography and clinical endpoints in trials of thromboprophylaxis in total hip replacement. J Bone Joint Surg Br 82: 480–482
Warwick D, Harrison J, Whitehouse S et al. (2002) A randomized comparison of a foot pump and low-molecular-weight heparin in the prevention of deep-vein thrombosis after total knee replacement. J Bone Joint Surg Br 84: 344–350
Warwick D (2003) Postoperative thromboprophylaxis – an orthopaedic surgeon’s view: Is it a valid concept in today’s practice? Curr Hematol Rep 2: 411–416
Warwick D (2004) New concepts in orthopaedic thrombosis prophylaxis. J Bone Joint Surg Br 86: 788–792
Wenzl ME, Leffringhausen W, Scherlitzky L (1996) Loss of extremities caused by Heparin-induced thrombocytopenia. Unfallchirurg 99(8): 607–611
Wilson SJ, Wilbur K, Burton E, Anderson DR (2001) Effect of patient weight on the anticoagulant response to adjusted therapeutic dosage of low-molecular-weight Heparin for the treatment of venous thromboembolism. Haemostasis 31(1): 2–8
Danksagung
Einen Dank für die Unterstützung möchten die Autoren Schwester Ingrid Moser und ihrem Team aus dem 1. Stock, Haus 1 (Department II) aussprechen.
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Ivanic, G.M., Moser, I., Homann, N.C. et al. Die intermittierende Impulskompression zur Abschwellung und Thromboseprophylaxe – Pilotstudie nach Hüft-TEP. Unfallchirurg 109, 786–792 (2006). https://doi.org/10.1007/s00113-006-1140-3
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DOI: https://doi.org/10.1007/s00113-006-1140-3