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Thymosin β4 and Ac-SDKP: Tools to mend a broken heart

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Abstract

Thymosin β4 – an endogenously occurring 43 amino acid peptide – has recently been shown to possess cardioprotective properties in the setting of acute myocardial infarction. This review focuses on the reported mechanisms of action through which Thymosin β4 might accomplish this effect and the clinical prospects for its use as a therapeutic agent.

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Authors and Affiliations

  1. UCL Institute of Child Health, 30 Guildford St, London, WC1N 1EH, UK

    Alex Rossdeutsch, Nicola Smart & Paul R. Riley

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  1. Alex Rossdeutsch
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  2. Nicola Smart
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Correspondence to Paul R. Riley.

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Rossdeutsch, A., Smart, N. & Riley, P.R. Thymosin β4 and Ac-SDKP: Tools to mend a broken heart. J Mol Med 86, 29–35 (2008). https://doi.org/10.1007/s00109-007-0243-9

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  • DOI: https://doi.org/10.1007/s00109-007-0243-9

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