Zusammenfassung
Die Erweiterung der infrarenalen Aorta auf einen Querdurchmesser von mindestens 3,0 cm wird als Aortenaneurysma definiert. Das infrarenale Aortenaneurysma ist eine häufige Erkrankung des älteren Menschen und für 1–3% der Todesfälle bei 65- bis 85-jährigen Männern verantwortlich. Die Erkrankung verläuft typischerweise symptomfrei, bis eine vital bedrohliche Ruptur auftritt. Daher ist das Screening nach einem Aortenaneurysma bei älteren Menschen und Patienten mit kardiovaskulären Risikofaktoren indiziert. Die Diagnose wird in der Regel sonographisch gestellt, zur Therapieplanung ist eine zusätzliche Bildgebung mittels Computertomographie (CT) oder Magnetresonanztomographie (MRT) notwendig. Ab einem Durchmesser von 5–5,5 cm sollte eine operative oder endovaskuläre Behandlung erfolgen. Welche Therapie im Einzelfall eingesetzt wird, hängt in erster Linie von der Co-Morbidität des Patienten und der anatomischen Struktur des Aneurysmas anhand der CT/MRT-Morphologie ab.
Abstract
An abdominal aortic aneurysm is defined as the increase of infrarenal aortic diameter of 3.0 cm and more. Infrarenal aortic aneurysm is frequent in the elderly and causes 1–3% of all deaths among men aged between 65 and 85 years. These aneurysms are typically asymptomatic until the life threatening event of rupture. Therefore screening of risk populations like elderly persons and persons with cardiovascular risk factors for aortic aneurysm seems to be most important. An aortic aneurysm is usually detected by sonography. An infrarenal aortic aneurysm with a diameter of 5.0–5.5 cm should be treated either with open surgical or endovascular therapy. If surgical or endovascular therapy is indicated, additional computer tomography (CT) or magnet resonance imaging (MRI) are necessary. The mode of treatment mainly depends on patient co-morbidity and on morphology of the aneurysm according to the CT/MRI-findings and should be determined individually.
Literatur
Agard C, Hamidou MA, Said L et al. (2007) Giant cell arteriitis: diagnosis, management, and cardiovascular implications. Rev Med Interne 28: 363–370
Berg P, Kaufmann D, van Marrewijk CJ, Buth J (2001) Spinal cord ischemia after Stent-graft treatment for infra-renal abdominal aortic aneurysms. Analysis of the Eurostar database. Eur J Vasc Endovasc Surg 22: 342–347
Blankensteijn JD, de Jong S, Prinssen M et al.; Dutch Randomized Endovascular Aneurysm Management (DREAM) Trial Group (2005) Two-year outcomes after conventional or endovascular repair of abdominal aortic aneurysms. N Engl J Med 352: 2398–2405
Elzouki AN, Ryden, Ahlgren A et al. (1999) Is there a relationship between abdominal aortic aneurysm and alpha1-antitrypsin deficiency (PiZ)? Eur J Vasc Endovasc Surg 17: 149–154
EVAR trial participants (2005) Endovascular aneurysm repair versus open repair in patients with abdominal aortic aneurysm (EVAR trial 1): randomised controlled trial. Lancet 365: 2179–2186
Glimaker H, Holmberg L, Elvin A et al. (1991) Natural history of patients with abdominal aortic aneurysm. Eur J Vasc Surg 5: 125–130
Hirsch AT, Haskal ZJ, Hertzer NR et al.; American Association for Vascular Surgery; Society for Vascular Surgery; Society for Cardiovascular Angiography and Interventions; Society for Vascular Medicine and Biology; Society of Interventional Radiology; ACC/AHA Task Force on Practice Guidelines Writing Committee to Develop Guidelines for the Management of Patients With Peripheral Arterial Disease; American Association of Cardiovascular and Pulmonary Rehabilitation; National Heart, Lung, and Blood Institute; Society for Vascular Nursing; TransAtlantic Inter-Society Consensus; Vascular Disease Foundation (2006) ACC/AHA 2005 Practice Guidelines for the Management of Patients With Peripheral Arterial Disease (lower extremity, renal, mesenteric, and abdominal aortic): A collaborative report from the American Associations for Vascular Surgery/Society for Vascular Surgery, Society for Cardiovascular Angiography and Interventions, Society for Vascular Medicine and Biology, Society of Interventional Radiology, and the ACC/AHA Task Force on Practice Guidelines (Writing Committee to develop guidelines for the management of patients with peripheral arterial disease). Circulation 113: e463–654
Kuivaniemi H, Shibamura H, Arthur C et al. (2003) Familial abdominal aortic aneurysms: Collection of 233 multiplex families. J Vasc Surg 37: 340–345
Lederle FA, Wilson SE, Johnson GR et al. (2002) Immediate repair compared with surveillance of small abdominal aortic aneurysms. N Engl J Med 346: 1437–1444
Limet R, Sakalihasan N, Alber A (1991) Determination of the expansion rate and incidence of rupture of abdominal aortic aneurysm. J Vasc Surg 14: 540–548
Lindholt JS, Vammen S, Fasting H et al. (2000) The plasma level of matrix metalloproteinase 9 may predict the natural history of small abdominal aortic aneurysms: a preliminary study. Eur J Endovasc Surg 20: 281–285
Mehard WB, Heiken JP, Sicard GA (1994) High-attenuating crescent in abdominal aortic aneurysm wall at CT: a sign of acute or impending rupture. Radiology 192: 359–362
Parodi JC, Palmatz JC, Barone HC (1991) Transfemoral intraluminal graft implantation for abdominal aortic aneurysms. Ann Vasc Surg 5: 491–499
Prance SE, Wilson YG, Cosgrove CM et al. (1999) Ruptured abdominal aortic aneurysms: selecting patients for surgery. Eur J Vasc Endovasc Surg 17: 129–132
Sakalihasan N, Limet R, Defawe OD (2005) Abdominal aortic aneurysm. Lancet 365: 1577–1589
Sakalihasan N, Van Damme H, Gomez P et al. (2002) Positron emission tomography (PET) evaluation of abdominal aortic aneurysm. Eur J Vasc Endovasc Surg 23: 431–436
Schumacher H, Eckstein HH, Kallinowski F, Allenberg JR (1997) Morphometry and classification in abdominal aortic aneurysms. J Endovasc Surg 4: 39–44
Singh K, Bonaa KH, Jacobsen BK et al. (2001) Prevalence and risk factors for abdominal aortic aneurysms in a population-based study: the Tromso Study. Am J Epidemiol 154: 236–244
Sonesson B, Lanne T, Hansen F, Sandgren T (1994) Infrarenal aortic diameter in the healthy person. Eur J Vasc Surg 8: 89–95
UK Small Aneurysm Trail Participants (1998) Mortality results for randomized controlled trial of early elective surgery or ultrasonographic surveillance for small abdominal aortic aneurysms. Lancet 352: 1649–1655
Verloes A, Sakalihasan N, Koulischer L, Limet R (1995) Aneurysms of the abdominal aorta: familial and genetic aspects in three hundred thirteen pedigrees. J Vasc Surg 21: 646–655
Zankl AR, Krumsdorf U, Katus HA et al. (2007) Pathology, natural history and treatment of abdominal aortic aneurysms. Clin Res Cardiol 96: 140–151
Danksagung
Die Autoren danken Frau Margot Neuser für die graphische Gestaltung der Abbildungen 1 und 8.
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Espinola-Klein, C., Neufang, A. & Düber, C. Infrarenales Aortenaneurysma. Internist 49, 955–966 (2008). https://doi.org/10.1007/s00108-008-2148-2
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DOI: https://doi.org/10.1007/s00108-008-2148-2