Skip to main content
Log in

Komplikationen bei Operationen an der Rhinobasis

Complications of anterior skull base surgery

  • Leitthema
  • Published:
HNO Aims and scope Submit manuscript

Zusammenfassung

Operationen der Rhinobasis werden zur Behandlung ernsthafter und komplizierter Krankheitsbilder durchgeführt und zählen zu den komplexen Eingriffen. Komplikationen sind bei diesen Eingriffen trotz erheblicher Fortschritte in den Operationstechniken relativ häufig und teilweise schwerwiegend. Die endoskopischen Operationstechniken der Rhinobasis scheinen seltener mit Komplikationen assoziiert zu sein als offene Operationsmethoden. Es werden verschiedene Klassifikationen zur Kategorisierung dieser Komplikationen vorgeschlagen, deren Anwendung beim Bericht über Komplikationsraten empfohlen werden kann. Zu den wichtigsten und häufigsten Komplikationen bei Rhinobasisoperationen zählen Blutungen, Liquorrhö, Meningitis und Hirnnervenschädigungen. Zur Vermeidung von Komplikationen sind eine sorgfältige Planung, eine enge interdisziplinäre Kooperation, die Kompetenz des Schädelbasiszentrums und seiner Mitarbeiter und ein stringentes Qualitätsmanagement von entscheidender Bedeutung. Im Hinblick auf die Häufigkeit und Schwere der möglichen Komplikationen spielt die sorgfältige und vollständige Aufklärung der Patienten eine zentrale Rolle.

Abstract

Anterior skull base operations are complex surgical procedures that are performed to treat serious and complicated diseases. Despite significant advances in surgical techniques, complications are relatively frequent and can be serious. Endoscopic skull base surgery seems to be associated with less complications than open techniques. Different classifications aimed at categorizing these complications have been suggested, the use of which can be recommended when reporting complication rates. The most relevant and frequent complications of anterior skull base surgery are hemorrhage, cerebrospinal fluid (CSF) leak, meningitis, and cranial nerve injury. Careful planning, close interdisciplinary cooperation, the competence of the skull base center and its members, and rigorous quality management are decisive for the avoidance of complications. With respect to the frequency and the seriousness of the complications, their meticulous and complete discussion with the patient before obtaining informed consent plays a central role.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Abb. 1
Abb. 2
Abb. 3
Abb. 4
Abb. 5

Literatur

  1. Barrow DL, Tindall GT (1990) Loss of vision after transsphenoidal surgery. Neurosurgery 27:60–68

    Article  PubMed  CAS  Google Scholar 

  2. Borg A, Kirkman MA, Choi D (2016) Endoscopic endonasal anterior skull base surgery: a systematic review of complications during the past 65 years. World Neurosurg 95:383–391

    Article  PubMed  Google Scholar 

  3. Ciric I, Ragin A, Baumgartner C, Pierce D (1997) Complications of transsphenoidal surgery: results of a national survey, review of the literature, and personal experience. Neurosurgery 40:225–236 (discussion 236–7)

    Article  PubMed  CAS  Google Scholar 

  4. Constantinidis J, Konstantinidis I (2017) Avoiding complications in endoscopic skull base surgery. Curr Opin Otolaryngol Head Neck Surg 25:79–85

    PubMed  Google Scholar 

  5. D’Anza B, Tien D, Stokken JK et al (2016) Role of lumbar drains in contemporary endonasal skull base surgery: meta-analysis and systematic review. Am J Rhinol Allergy 30:430–435

    Article  PubMed  Google Scholar 

  6. Diaz L, Mady LJ, Mendelson ZS et al (2015) Endoscopic ventral skull base surgery: Is early postoperative imaging warranted for detecting complications? Laryngoscope 125:1072–1076

    Article  PubMed  Google Scholar 

  7. Dichgans M, Forsting M, Hamann G et al (2012) Intrazerebrale Blutung. In: Diener HC, Weimar C (Hrsg) Leitlinien für Diagnostik und Therapie in der Neurologie. Thieme, Stuttgart

    Google Scholar 

  8. Dolci RLL, Miyake MM, Tateno DA et al (2016) Postoperative otorhinolaryngologic complications in transnasal endoscopic surgery to access the skull base. Braz J Otorhinolaryngol 83:349–355

    Article  PubMed  Google Scholar 

  9. Gil Z, Patel SG, Bilsky M et al (2009) Complications after craniofacial resection for malignant tumors: are complication trends changing? Otolaryngol Head Neck Surg 140:218–223

    Article  PubMed  Google Scholar 

  10. Hadad G, Bassagasteguy L, Carrau RL et al (2006) A novel reconstructive technique after endoscopic expanded endonasal approaches: vascular pedicle nasoseptal flap. Laryngoscope 116:1882–1886

    Article  PubMed  Google Scholar 

  11. Haynes AB, Weiser TG, Berry WR et al (2009) A surgical safety checklist to reduce morbidity and mortality in a global population. N Engl J Med 360:491–499

    Article  PubMed  CAS  Google Scholar 

  12. Hosemann W, Schroeder H, Schroeder HWS (2015) Rhino-Neurochirurgie. Laryngorhinootologie 94(Suppl 1):S153–S205

    PubMed  Google Scholar 

  13. Johans SJ, Burkett DJ, Swong KN et al (2018) Antibiotic prophylaxis and infection prevention for endoscopic endonasal skull base surgery: our protocol, results, and review of the literature. J Clin Neurosci 47:249–253

    Article  PubMed  Google Scholar 

  14. Kassam AB, Prevedello DM, Carrau RL et al (2011) Endoscopic endonasal skull base surgery: analysis of complications in the authors’ initial 800 patients. J Neurosurg 114:1544–1568

    Article  PubMed  Google Scholar 

  15. Lai L, Morgan MK, Trooboff S, Harvey RJ (2013) A systematic review of published evidence on expanded endoscopic endonasal skull base surgery and the risk of postoperative seizure. J Clin Neurosci 20:197–203

    Article  PubMed  Google Scholar 

  16. Leibu S, Rosenthal G, Shoshan Y, Benifla M (2017) Clinical significance of long-term follow-up of children with posttraumatic skull base fracture. World Neurosurg 103:315–321

    Article  PubMed  Google Scholar 

  17. Leong SC (2013) A systematic review of surgical outcomes for advanced juvenile nasopharyngeal angiofibroma with intracranial involvement. Laryngoscope 123:1125–1131

    Article  PubMed  Google Scholar 

  18. Mendelson ZS, Echanique KA, Crippen MM et al (2017) Utility of early postoperative imaging after combined endoscopic and open ventral skull base surgery. Am J Rhinol Allergy 31:186–189

    Article  PubMed  Google Scholar 

  19. Miller JD, Taylor RJ, Ambrose EC et al (2017) Complications of open approaches to the skull base in the endoscopic era. J Neurol Surg B Skull Base 78:11–17

    Article  PubMed  Google Scholar 

  20. Miranda AH, Castellar-Leones SM, Elzain MA, Moscote-Salazar LR (2013) Brain abscess: current management. J Neurosci Rural Pract 4:67–81

    Google Scholar 

  21. Nadimi S, Caballero N, Carpenter P et al (2014) Immediate postoperative imaging after uncomplicated endoscopic approach to the anterior skull base: is it necessary? Int Forum Allergy Rhinol 4:1024–1029

    Article  PubMed  Google Scholar 

  22. Oakley GM, Orlandi RR, Woodworth BA et al (2016) Management of cerebrospinal fluid rhinorrhea: an evidence-based review with recommendations. Int Forum Allergy Rhinol 6:17–24

    Article  PubMed  Google Scholar 

  23. Padhye V, Valentine R, Sacks R, Ooi EH, Teo C, Tewfik M et al (2015) Coping with catastrophe: the value of endoscopic vascular injury training. Int Forum Allergy Rhinol 5:247–252

    Article  PubMed  Google Scholar 

  24. Ramakrishnan VR, Kingdom TT, Nayak JV et al (2012) Nationwide incidence of major complications in endoscopic sinus surgery. Int Forum Allergy Rhinol 2:34–39

    Article  PubMed  Google Scholar 

  25. Ratilal BO, Costa J, Pappamikail L, Sampaio C (2015) Antibiotic prophylaxis for preventing meningitis in patients with basilar skull fractures. Cochrane Database Syst Rev. https://doi.org/10.1002/14651858.CD004884.pub4

    Article  PubMed  Google Scholar 

  26. Stokken J, Recinos PF, Woodard T, Sindwani R (2015) The utility of lumbar drains in modern endoscopic skull base surgery. Curr Opin Otolaryngol Head Neck Surg 23:78–82

    PubMed  Google Scholar 

  27. Sudhakar N, Ray A, Vafidis JA (2004) Complications after trans-sphenoidal surgery: our experience and a review of the literature. Br J Neurosurg 18:507–512

    Article  PubMed  CAS  Google Scholar 

  28. Valentine R, Wormald PJ (2011) A vascular catastrophe during endonasal surgery: an endoscopic sheep model. Skull Base 21:109–114

    Article  PubMed  PubMed Central  Google Scholar 

  29. Valentine R, Padhye V, Wormald PJ (2016) Simulation training for vascular emergencies in endoscopic sinus and skull base surgery. Otolaryngol Clin North Am 49:877–887

    Article  PubMed  Google Scholar 

  30. Wagenmann M, Schipper J (2011) Die transnasale Route zur Schädelbasis. Von der Nasennebenhöhlenchirurgie zur Schädelbasischirurgie. Laryngorhinootologie 90(Suppl 1):S1–S15

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to M. Wagenmann.

Ethics declarations

Interessenkonflikt

M. Wagenmann hat Gelder für Studiendurchführung, Berater- und/oder Gutachtertätigkeit, Vortrags- und/oder Schulungstätigkeiten und/oder bezahlte Mitarbeit in einem wissenschaftlichen Beirat erhalten von den Firmen: ALK-Abelló, Allakos, Allergopharma, AstraZeneca, Bencard Allergie, Bionorica SE, Biotech Tools, DüsseldorfCongress Veranstaltungsgesellschaft, GlaxoSmithKline, HAL Allergie, Meda Pharma, Otonomy, Sanofi-Aventis, Stallergenes, Strekin, TEVA. Ein direkter Interessenkonflikt besteht nicht.

K. Scheckenbach ist Mitinhaberin eines Patents auf RAD51c, das vorübergehend an Myriad Genetics veräußert war. Ein direkter Interessenkonflikt besteht nicht.

B. Kraus und I. Stenin geben an, dass kein Interessenkonflikt besteht.

Dieser Beitrag beinhaltet keine von den Autoren durchgeführten Studien an Menschen oder Tieren.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Wagenmann, M., Scheckenbach, K., Kraus, B. et al. Komplikationen bei Operationen an der Rhinobasis. HNO 66, 438–446 (2018). https://doi.org/10.1007/s00106-018-0508-3

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00106-018-0508-3

Schlüsselwörter

Keywords

Navigation