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Die lokale Anwendung von Tranexamsäure in der HNO-Chirurgie

Local use of tranexamic acid in ENT surgery

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Zusammenfassung

Blutungen gehören zu den wesentlichsten Komplikationen in der HNO-Chirurgie, vor allem während und nach endonasalen/oralen Eingriffen. Basierend auf den guten Ergebnissen bei der lokalen Anwendung von Tranexamsäure nach Zahnextraktionen werden die verschiedenen Anwendungsmöglichkeiten in der HNO-Chirurgie diskutiert und die aktuelle Literatur dargestellt. Nach unseren Erfahrungen kann die Nachblutungsrate nach oralen und nasalen Eingriffen durch die lokale Anwendung von Tranexamsäure deutlich reduziert werden, was vor allem bei den immer älter werdenden Patienten eine Risikominimierung und bessere postoperative Compliance bedeutet. Unsere Erfahrungen fordern dazu auf, den Nutzen von der lokalen Anwendung von Tranexamsäure in der HNO-Chirurgie weiter zu untersuchen.

Abstract

Bleeding is a main complication in ENT surgery especially in oral and nasal interventions. Based on good results in local application of tranexamic acid after dental extraction, the different possibilities of local application of tranexamic acid in ENT surgery are discussed and the current literature is presented. In our experience, the rate of secondary hemorrhage after oral and nasal interventions can be reduced considerably by local application of tranexamic acid, which means risk reduction and better compliance especially in an increasingly aging patient population. Based on our experience, the local use of tranexamic acid in ENT surgery should be the focus of future studies.

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Authors and Affiliations

  1. Belegabteilung für HNO-Heilkunde, Kopf-und Halschirurgie, Plastische Operationen, endokrine Halschirurgie, St.-Barbara-Klinik, Am Heessener Wald 1, 59073, Hamm, Deutschland

    J. Abrams

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  1. J. Abrams
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Correspondence to J. Abrams.

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Abrams, J. Die lokale Anwendung von Tranexamsäure in der HNO-Chirurgie. HNO 60, 1014–1018 (2012). https://doi.org/10.1007/s00106-012-2528-8

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  • DOI: https://doi.org/10.1007/s00106-012-2528-8

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