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Gutartige Hauttumoren bei Kindern

Benign skin neoplasms in children

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Zusammenfassung

Hauttumoren bei Kindern sind variantenreich und zeigen meist gutartige Verläufe. Dermatologen sollten die zahlreichen gutartigen Hauttumoren zu differenzieren wissen und in der Lage sein, den besorgten Patienten die optimale Behandlung zu empfehlen. Eine chirurgische Entfernung der gutartigen Hauttumoren ist oft die einzige Therapiemöglichkeit. Ziel dieser Publikation ist es, einen Gesamtüberblick zu geben über die epidermalen Tumoren (z. B. „inflammatory linear verrucous epidermal nevus“ [ILVEN], Naevus sebaceus), Tumoren der epidermalen Anhangsgebilde (z. B. Pilomatrixom), dermalen Tumoren (z. B. Angiofibrom), Fibromatosen (z. B. Fingerknöchelpolster), Tumoren des Fett‑, Muskel oder Knochengewebes (z. B. Osteoma cutis, subunguale Exostose), Epidermalzysten und Pseudozysten und pathologische Fibrosierung als Reaktionen nach Hautverletzungen (Keloid). Wissenschaftliche Daten hierzu sind rar, und erst im letzten Jahrzehnt machten es histopathologische Untersuchungen und genetische Studien zusammen mit ausführlicher Phänotypisierung möglich, ein neues Verständnis der pathogenetischen Mechanismen zu gewinnen.

Abstract

There are many different types of skin neoplasms in children and most are benign. Dermatologists should be able to differentiate between the various types of benign skin neoplasms and be able to recommend optimal treatment to concerned patients. Surgical removal of benign skin neoplasms is often the only treatment option. The aim of this paper is to provide a general overview of epidermal lesions (e.g., inflammatory linear verrucous epidermal nevus [ILVEN], nevus sebaceous), tumors of the epidermal appendages (e.g. pilomatrixoma), cutaneous neoplasms (e.g. angiofibroma), fibromatoses (e.g., knuckle pads), tumors comprised of fat, muscle, or bone tissue (e.g., osteoma cutis, subungual exostosis), epidermal cysts and pseudocysts, and pathologic fibrosis reactions after dermal injury (keloid). Scientific data are scarce and only in the last decade has it been possible to perform histopathological examinations and genetic studies together with detailed phenotyping to gain new understanding of the pathogenetic mechanisms.

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  1. Carmen Maria Salavastru

    Present address: Dermatologie II, Colentina Klinik, Carol-Davila-Universität für Medizin und Pharmazie, Stefan cel Mare Street 19–21, 020125, Bukarest, Rumänien

Authors and Affiliations

  1. Pädiatrische Dermatologie, Dermatoonkologisches Forschungungslabor, Colentina Klinik, Carol-Davila-Universität für Medizin und Pharmazie, Bukarest, Rumänien

    Carmen Maria Salavastru

  2. Dermatologie II, Colentina Klinik, Carol-Davila-Universität für Medizin und Pharmazie, Stefan cel Mare Street 19–21, 020125, Bukarest, Rumänien

    Alexandra-Irina Butacu, Klaus Fritz & George-Sorin Tiplica

  3. Hautärzte und Laserzentrum Landau, Landau, Deutschland

    Klaus Fritz & Seher Eren

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Übersetzung aus dem Englischen: Prof. Dr. Klaus Fritz

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Salavastru, C.M., Butacu, AI., Fritz, K. et al. Gutartige Hauttumoren bei Kindern. Hautarzt 73, 127–137 (2022). https://doi.org/10.1007/s00105-021-04935-w

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