Zusammenfassung
Trotz einiger hoffnungsvoller therapeutischer Entwicklungen, wie z. B. die Lokaltherapie mit einer Salbe aus Derivaten des grünen Tees, bleibt die Therapie der anogenitalen Warzen ein Problem. Sowohl ärztliche Behandlungen als auch die Selbstbehandlung durch die Patienten sind nicht völlig zufriedenstellend. Die aktuellen Therapieformen mit hohen Rezidivquoten zusammen mit der zunehmenden Inzidenz und Krankheitslast sind Indikatoren dafür, dass die quadrivalente prophylaktische VLP („virus like particle“)-HPV-6-, -11-, -16-, -18-Vakzine zur Kontrolle HPV-assoziierter Neoplasien wie anogenitale Warzen vermehrt eingesetzt werden sollte.
Abstract
Despite some recent hopeful therapeutic developments such as topical green tea derivatives, the therapy of anogenital warts remains a medical problem. Both physician- and self-administered therapeutic approaches are not fully satisfactory. The high recurrence rates associated with the current therapy of anogenital warts together with their increasing incidence and burden of disease further support the use of the prophylactic quadrivalent VLP HPV 6,11,16,18 vaccine for control of HPV-associated neoplasias in women and men.
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Interessenkonflikt
Der korrespondierende Autor weist auf folgende Beziehungen hin: G.G. hat Honorare für Vorträge über die Entwicklung und Anwendung der HPV-Vakzine von Sanofi Pasteur MSD und für die Therapie genitoanaler Warzen mit Polyphenon E von Abbott erhalten.
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Gross, G. Konservative Behandlungsmethoden anogenitaler HPV-Infektionen. Hautarzt 62, 34–39 (2011). https://doi.org/10.1007/s00105-010-2036-2
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DOI: https://doi.org/10.1007/s00105-010-2036-2