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Psychoonkologische Aspekte des malignen Melanoms

Ergebnisse eines systematischen Reviews von 1990–2008

Psycho-oncological aspects of malignant melanoma

A systematic review from 1990–2008

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Zusammenfassung

Hintergrund und Methoden

Trotz steigender Prävalenz des malignen Melanoms fanden psychoonkologische Aspekte vergleichsweise wenig Beachtung. Ziel der Literatursuche war eine systematische Übersicht über alle publizierten psychoonkologischen Arbeiten zu Patienten mit einem malignen Melanom (MM).

Ergebnisse

Von 31 Studien untersuchen 12 die Lebensqualität bei MM-Patienten, 6 bezogen auf den Verlauf der Therapie. Die meisten Studien liegen aus dem englischsprachigen Raum (USA, UK, AU) vor; wenige Studien kamen aus Deutschland. Die methodische Qualität (Querschnittserhebung, fehlende Rücklaufquote, geringe Fallzahlen) und die Vergleichbarkeit der Studien (heterogene, nicht standardisierte Messverfahren) sind begrenzt.

Schlussfolgerungen

Psychosoziale Merkmale (Krankheitsbewältigung, soziale Unterstützung) haben über das Tumorstadium hinaus einen wesentlichen Einfluss auf die Lebensqualität. Ermutigende Ergebnisse finden sich zur Psychotherapie von MM-Patienten. Angesichts der insgesamt guten Überlebenswahrscheinlichkeit des MM sind Lebensqualität und Betreuungsbedarf von langzeitüberlebenden Patienten zu bestimmen.

Abstract

Background and Methods

Despite the increasing prevalence of malignant melanoma, psychosocial aspects have found little attention. A systematic review was conducted in order to identify psycho-oncological articles on patients with malignant melanoma.

Results

Out of a total of 31 studies, 12 examine quality of life in malignant melanoma patients and 6 studies monitor quality of life in the course of therapy. Most studies originate from English-speaking countries (USA, UK, AU); few German studies have been published. Methodological limitations of the studies include cross-sectional assessment, unreported return rate, small sample sizes and comparability (heterogeneous or non-standardized psychosocial measures).

Conclusions

In addition to the tumor stage, psychosocial characteristics (coping with disease, social support) have a substantial effect on quality of life. Results from psychotherapy trials with malignant melanoma patients are encouraging. Given the overall high survival rates of malignant melanoma, quality of life and needs for care of long-term survivors need to be assessed.

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Authors and Affiliations

  1. Klinik und Poliklinik für Psychosomatische Medizin und Psychotherapie, Universitätsmedizin Mainz, Untere Zahlbacher Str. 8, 55131, Mainz, Deutschland

    M.E. Beutel & H. Marian

  2. Institut für Medizinische Biometrie, Epidemiologie und Informatik, Mainz, Deutschland

    M. Blettner

  3. Schwerpunkt Medizinische Psychologie und Medizinische Soziologie, Mainz, Deutschland

    S. Fischbeck

  4. Hautklinik, Universitätsmedizin Mainz, Mainz, Deutschland

    C. Loquay

  5. Koordinationsstelle Psychosoziale Versorgung Tumorzentrum Rheinland-Pfalz e.V., Mainz, Deutschland

    A. Werner

Authors
  1. M.E. Beutel
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  2. M. Blettner
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  3. S. Fischbeck
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  4. C. Loquay
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  5. A. Werner
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  6. H. Marian
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Correspondence to M.E. Beutel.

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Beutel, M., Blettner, M., Fischbeck, S. et al. Psychoonkologische Aspekte des malignen Melanoms. Hautarzt 60, 727–734 (2009). https://doi.org/10.1007/s00105-009-1814-1

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  • DOI: https://doi.org/10.1007/s00105-009-1814-1

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