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Vitiligo

Diagnose, Differenzialdiagnose und aktuelle Therapieempfehlungen

Vitiligo

Diagnosis, differential diagnosis, and current patient management

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Zusammenfassung

Die Vitiligo ist eine bis heute nicht heilbare Pigmentstörung mit Auftreten lokalisierter bis generalisierter Depigmentierungen und chronischem, zumeist progressivem Verlauf. Sie kann Teil eines polygenen, multifaktoriell vererbten Erkrankungsbildes sein mit erhöhter Bereitschaft zu Autoimmunerkrankungen, deren Vorliegen abgeklärt werden sollte. Abhängig vom Alter und Leidensdruck des Patienten, vom Ausmaß der betroffenen Körperoberfläche, von der Art der betroffenen Lokalisationen und von der Aktivität der Vitiligo, können durch verschiedene konservative und operative Therapiemaßnahmen Teilerfolge erzielt werden. Wie stabil eine therapeutisch induzierte Repigmentierung ist und inwieweit die heute zur Verfügung stehenden Therapieoptionen den weiteren Verlauf der Vitiligo beeinflussen, ist nicht bekannt.

Abstract

Vitiligo is characterized by patches of depigmented skin in a localized to generalized distribution. Up to now, vitiligo is not curable and mostly has a chronic and progressive course. The disorder may be part of a polygenic, multifactorial transmitted disease with an increased disposition to autoimmune disorders, which should be screened for. Depending on the age of the patient, the psychological strain, the location, the body surface area involved, and the disease activity, several conservative as well as surgical therapeutic options may be partially successful. How long the induced repigmentation remains and the effect of the available therapeutic options on the natural history of vitiligo remain to be clarified.

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  1. Hautklinik, Universitätsklinikum Erlangen, Hartmannstraße 14, 91052, Erlangen, Deutschland

    A. Hartmann

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  1. A. Hartmann
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Hartmann, A. Vitiligo. Hautarzt 60, 505–515 (2009). https://doi.org/10.1007/s00105-009-1770-9

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  • DOI: https://doi.org/10.1007/s00105-009-1770-9

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