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Fraktionierte Photothermolyse

Fractional Photothermolysis

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Zusammenfassung

Die fraktionierte Photothermolyse (FP) wurde vor kurzem als neues Konzept in der dermatologischen Lasermedizin eingeführt. FP beruht auf einer durch fokussierte Laserstrahlen erzeugten Vielzahl von mikroskopisch kleinen Nekrosezonen – den „Microscopic Treatment Zones“ (MTZ). Obgleich das epidermale und dermale Gewebe innerhalb der einzelnen MTZs komplett zerstört wird, heilt ein solches mikroskopisches 3-dimensionales Schadenmuster schnell und mit geringen Nebenwirkungen. FP wird zurzeit erfolgreich zur Behandlung von gering ausgeprägten Falten, lichtgeschädigter Haut, Aknenarben und Melasma eingesetzt. Durch die Kombination aus relativ guter klinischer Effektivität und dem günstigen Nebenwirkungsprofil konnte sich FP in den letzten 2 Jahren als Behandlungsalternative zu den risiko- und nebenwirkungsreicheren ablativen Laserverfahren etablieren.

Abstract

Fractional photothermolysis (FP) has been recently introduced as a new concept in dermatologic laser medicine. FP employs an array of small laser beams to create many microscopic areas of thermal necrosis within the skin called microscopic treatment zones (MTZ). Even though FP completely destroys the epidermis and dermis within these MTZ, the 3-dimensional pattern of damage heals quickly and with few side effects. FP is currently used to treat fine wrinkles, photodamaged skin, acne scars, and melasma. Due to its clinical efficacy and limited side effects FP has established itself in the past two years as an alternative treatment modality to the conventional ablative and non ablative laser therapy.

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Abbreviations

FP:

Fraktionierte Photothermolyse

FR:

Fraktioniertes Resurfacing

MTZ:

„Microscopic Treatment Zone“

MEND:

„Microscopic-Epidermal-Necrotic-Debris“

FDA:

Food and Drug Administration

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Interessenkonflikt

D. Manstein erhält Royalties von Reliant Technologies. Der korrespondierende Autor gibt an, dass kein Interessenkonflikt besteht.

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Authors and Affiliations

  1. Hautklinik der Universität Münster, Von-Esmarch-Straße 58, 48149, Münster, Deutschland

    Hans-Joachim Laubach

  2. Wellman Center for Photomedicine, Massachusetts General Hospital and Harvard Medical School, 50 Blossom Street, Boston, MA 02114, USA

    Hans-Joachim Laubach & D. Manstein

Authors
  1. Hans-Joachim Laubach
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  2. D. Manstein
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Correspondence to Hans-Joachim Laubach.

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Laubach, HJ., Manstein, D. Fraktionierte Photothermolyse. Hautarzt 58, 216–223 (2007). https://doi.org/10.1007/s00105-007-1286-0

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  • DOI: https://doi.org/10.1007/s00105-007-1286-0

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