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Livedovaskulopathie bei heterozygoter Faktor-V-Leiden-Mutation und Sticky-Platelet-Syndrom

Livedoid vasculopathy with heterozygous factor V Leiden mutation and sticky platelet syndrome

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Zusammenfassung

Wir berichten über einen 64-jährigen Patienten mit schmerzhaften Ulzerationen sowie einer Livedo racemosa im Bereich beider Beine. In der Vorgeschichte waren mehrere Apoplexe sowie ein Myokardinfarkt bekannt. Dermatohistologische Untersuchungen und gerinnungsphysiologische Analysen ergaben die Diagnose einer Livedovaskulopathie bei heterozygoter Faktor-V-Leiden-Mutation und Sticky-Platelet-Syndrom Typ II. Die systemische Gabe von Azetylsalizylsäure und Heparin sowie eine desinfizierende und granulationsfördernde Lokaltherapie führten zu einer Verbesserung des Hautbefundes.

Abstract

A 64-year-old male patient presented with painful ulcerations and livedo racemosa of both lower limbs. He had a history of cerebral and myocardial infarctions. Dermatohistologic findings and laboratory tests of the patient’s coagulation system revealed the diagnosis of livedoid vasculopathy with heterozygous factor V Leiden mutation and sticky platelet syndrome type II. Systemic treatment with acetylsalicylic acid and heparin as well as topical therapy with disinfectant and granulation-inducing agents resulted in improvement of the skin lesions.

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Authors and Affiliations

  1. Hautklinik, Universitätsklinikum Düsseldorf, Düsseldorf

    V. Lewerenz, T. Burchardt, A. Büchau, T. Ruzicka &  M. Megahed

  2. Hautklinik, Universitätsklinikum Düsseldorf, Moorenstraße 5, 40225 , Düsseldorf

    M. Megahed

Authors
  1. V. Lewerenz
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  2. T. Burchardt
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  3. A. Büchau
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  4. T. Ruzicka
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  5. M. Megahed
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Correspondence to M. Megahed.

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Lewerenz, V., Burchardt, T., Büchau, A. et al. Livedovaskulopathie bei heterozygoter Faktor-V-Leiden-Mutation und Sticky-Platelet-Syndrom. Hautarzt 55, 379–381 (2004). https://doi.org/10.1007/s00105-004-0709-4

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  • DOI: https://doi.org/10.1007/s00105-004-0709-4

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