Skip to main content
Log in

Aktuelle Studienlage zum Bauchdeckenverschluss

Klassische Nahttechniken

Current standards of abdominal wall closure techniques

Conventional suture techniques

  • Leitthema
  • Published:
Der Chirurg Aims and scope Submit manuscript

Zusammenfassung

Hintergrund

Zu den häufigsten Komplikationen nach abdominalchirurgischen Eingriffen mittels Laparotomie gehören Narbenhernien und Wundinfektionen, welche in mehr als 10–15 % der Fälle auftreten. Das Risiko dieser Komplikationen lässt sich durch chirurgische Technik und die Verwendung von speziellem Nahtmaterial jedoch reduzieren. Im Jahr 2010 ergab die INLINE-Metaanalyse des Studienzentrums der Deutschen Gesellschaft für Chirurgie (SDGC), dass eine fortlaufende Nahttechnik mit einem langsam resorbierbaren Nahtmaterial die besten Ergebnisse nach elektiver medianer Laparotomie in Bezug auf das Narbenhernienrisiko zeigt.

Ziel der Arbeit

Ziel dieser Arbeit soll eine Aktualisierung der INLINE-Metaanalyse sein. Dazu sollen mittels einer systematischen Literaturrecherche alle randomisiert-kontrollierten Studien (RCT) erfassen werden, die seit 2010 zum Thema Bauchdeckenverschluss veröffentlicht wurden, um so den aktuellen Stand der Evidenz zu den konventionellen Nahttechniken zusammenfassend darzustellen.

Material und Methoden

Am 28.01.2016 erfolgte eine systematische Literaturrecherche über „MEDLINE“ und das „Cochrane Central Register of Controlled Trials“ (CENTRAL). Hierüber wurden alle verfügbaren RCTs zu chirurgischen Techniken des Bauchdeckenverschlusses identifiziert und eingeschlossen.

Ergebnisse

Seit 2010 wurden neun RCTs identifiziert, die verschiedene Techniken zum Bauchdeckenverschluss verglichen. In drei monozentrischen RCTs zum Vergleich von Nahtmaterialien nach Laparotomie ergaben sich keine neuen Erkenntnisse zur INLINE-Metaanalyse, sodass weiterhin ein langsam resorbierbarer Faden in fortlaufender Technik zum Erreichen einer möglichst niedrigen Narbenhernienrate empfohlen werden kann. Des Weiteren wurden sechs RCTs zum Thema antimikrobielle Beschichtung gefunden, die insgesamt keinen signifikanten Vorteil in Bezug auf Wundinfektionen durch Triclosan-Nahtmaterial zeigen konnten.

Diskussion

Die aktuelle Studienlage ergibt, dass weiterhin ein langsam resorbierbares, monofiles Nahtmaterial in fortlaufender Nahttechnik bei der elektiven medianen Laparotomie die besten Ergebnisse zeigt. Triclosan-beschichtete Nahtmaterialien können zu einer Reduktion der Wundinfektionsrate nicht empfohlen werden. Für Notfalllaparotomien konnte bisher kein Vorteil für eine bestimmte Nahttechnik oder ein spezielles Nahtmaterial gezeigt werden.

Abstract

Background

The most frequent complications following midline abdominal laparotomy include incisional hernias, which develop in 10–15 % of patients and surgical site infections in 15–25 % of cases; however, the risk of these complications can be reduced by the surgical technique and the use of special suture materials. In 2010, the INLINE meta-analysis performed by the Study Centre of the German Society of Surgery (SDGC) revealed that a continuous suture technique using slowly absorbable suture material resulted in the lowest risk of developing postoperative incisional hernia after elective midline laparotomy.

Objective

The aim of this study was to perform a systematic literature search to identify all randomized controlled trials (RCTs) that have been published since 2010 concerning conventional abdominal wall closure in order to update the 2010 INLINE meta-analysis and summarize current evidence.

Material and methods

On 28 January 2016, a systematic literature search was performed in MEDLINE and the Cochrane Central Register of Controlled Trials (CENTRAL). All RCTs dealing with abdominal wall closure after midline laparotomy were identified and included for further analysis.

Results

Since 2010 a total of 9 RCTs comparing different techniques of abdominal wall closure have been published. Three monocentric RCTs comparing different suture materials, showed no significant differences to the INLINE meta-analysis regarding incisional hernia development; therefore, slowly absorbable sutures using a continuous suture technique are still recommended for abdominal wall closure in elective cases. Furthermore, six RCTs were identified which investigated antimicrobial suture materials but failed to show an overall advantage for Triclosan-coated suture material with respect to surgical site infections.

Conclusion

Current evidence shows that slowly absorbable monofilament suture material using a continuous suture technique provides the best results with regard to incisional hernia rates after elective midline laparotomy. Triclosan-coated sutures cannot be recommended as a standard suture material as they failed to reduce surgical site infections. For emergency laparotomies no evidence exists to recommend a specific kind of suture technique or a special suture material.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Literatur

  1. Baracs J, Huszar O, Sajjadi SG et al (2011) Surgical site infections after abdominal closure in colorectal surgery using triclosan-coated absorbable suture (PDS Plus) vs. uncoated sutures (PDS II): a randomized multicenter study. Surg Infect 12:483–489

    Article  Google Scholar 

  2. Bennett-Guerrero E, Pappas TN, Koltun WA et al (2010) Gentamicin-collagen sponge for infection prophylaxis in colorectal surgery. N Engl J Med 363:1038–1049

    Article  CAS  PubMed  Google Scholar 

  3. Bloemen A, Van Dooren P, Huizinga BF et al (2011) Randomized clinical trial comparing polypropylene or polydioxanone for midline abdominal wall closure. Br J Surg 98:633–639

    Article  CAS  PubMed  Google Scholar 

  4. Statistisches Bundesamt (2014) Die 20 häufigsten Operationen

    Google Scholar 

  5. Culver DH, Horan TC, Gaynes RP et al (1991) Surgical wound infection rates by wound class, operative procedure, and patient risk index. National Nosocomial Infections Surveillance System. Am J Med 91:152S–157S

    Article  CAS  PubMed  Google Scholar 

  6. Darouiche RO, Wall MJ Jr, Itani KM et al (2010) Chlorhexidine-alcohol versus povidone-iodine for surgical-site antisepsis. N Engl J Med 362:18–26

    Article  CAS  PubMed  Google Scholar 

  7. Diener MK, Knebel P, Kieser M et al (2014) Effectiveness of triclosan-coated PDS Plus versus uncoated PDS II sutures for prevention of surgical site infection after abdominal wall closure: the randomised controlled PROUD trial. Lancet 384:142–152

    Article  CAS  PubMed  Google Scholar 

  8. Diener MK, Voss S, Jensen K et al (2010) Elective midline laparotomy closure: the INLINE systematic review and meta-analysis. Ann Surg 251:843–856

    Article  PubMed  Google Scholar 

  9. Ellis H, Heddle R (1977) Does the peritoneum need to be closed at laparotomy? Br J Surg 64:733–736

    Article  CAS  PubMed  Google Scholar 

  10. Fink C, Baumann P, Wente MN et al (2014) Incisional hernia rate 3 years after midline laparotomy. Br J Surg 101:51–54

    Article  CAS  PubMed  Google Scholar 

  11. Hugh TB, Nankivell C, Meagher AP et al (1990) Is closure of the peritoneal layer necessary in the repair of midline surgical abdominal wounds? World J Surg 14:231–233 (discussion 233–234)

    Article  CAS  PubMed  Google Scholar 

  12. Itani KM, Wilson SE, Awad SS et al (2006) Ertapenem versus cefotetan prophylaxis in elective colorectal surgery. N Engl J Med 355:2640–2651

    Article  CAS  PubMed  Google Scholar 

  13. Justinger C, Moussavian MR, Schlueter C et al (2009) Antibacterial [corrected] coating of abdominal closure sutures and wound infection. Surgery 145:330–334

    Article  PubMed  Google Scholar 

  14. Justinger C, Slotta JE, Ningel S et al (2013) Surgical-site infection after abdominal wall closure with triclosan-impregnated polydioxanone sutures: results of a randomized clinical pathway facilitated trial (NCT00998907). Surgery 154:589–595

    Article  PubMed  Google Scholar 

  15. Kingsnorth A, Leblanc K (2003) Hernias: inguinal and incisional. Lancet 362:1561–1571

    Article  PubMed  Google Scholar 

  16. Mattavelli I, Rebora P, Doglietto G et al (2015) Multi-center randomized controlled trial on the effect of triclosan-coated sutures on surgical site infection after colorectal surgery. Surg Infect (Larchmt) 16:226–235

    Article  Google Scholar 

  17. Mihaljevic AL, Muller TC, Kehl V et al (2015) Wound edge protectors in open abdominal surgery to reduce surgical site infections: a systematic review and meta-analysis. PLoS ONE 10:e0121187

    Article  PubMed  PubMed Central  Google Scholar 

  18. Mihaljevic AL, Schirren R, Ozer M et al (2014) Multicenter double-blinded randomized controlled trial of standard abdominal wound edge protection with surgical dressings versus coverage with a sterile circular polyethylene drape for prevention of surgical site infections: a CHIR-Net trial (BaFO; NCT01181206). Ann Surg 260:730–737

    Article  PubMed  Google Scholar 

  19. Muysoms FE, Antoniou SA, Bury K et al (2015) European Hernia Society guidelines on the closure of abdominal wall incisions. Hernia 19:1–24

    Article  CAS  PubMed  Google Scholar 

  20. Nakamura T, Kashimura N, Noji T et al (2013) Triclosan-coated sutures reduce the incidence of wound infections and the costs after colorectal surgery: a randomized controlled trial. Surgery 153:576–583

    Article  PubMed  Google Scholar 

  21. Ohira G, Kawahira H, Miyauchi H et al (2015) Synthetic polyglycomer short-term absorbable sutures vs. polydioxanone long-term absorbable sutures for preventing incisional hernia and wound dehiscence after abdominal wall closure: a comparative randomized study of patients treated for gastric or colon cancer. Surg Today 45:841–845

    Article  CAS  PubMed  Google Scholar 

  22. Pandey S, Singh M, Singh K et al (2013) A prospective randomized study comparing non-absorbable polypropylene (Prolene(R)) and delayed absorbable polyglactin 910 (Vicryl(R)) suture material in mass closure of vertical laparotomy wounds. Indian J Surg 75:306–310

    Article  PubMed  Google Scholar 

  23. Rahbari NN, Knebel P, Kieser M et al (2012) Design and current status of CONTINT: continuous versus interrupted abdominal wall closure after emergency midline laparotomy – a randomized controlled multicenter trial [NCT00544583]. Trials 13:72

    Article  PubMed  PubMed Central  Google Scholar 

  24. Rasic Z, Schwarz D, Adam VN et al (2011) Efficacy of antimicrobial triclosan-coated polyglactin 910 (Vicryl* Plus) suture for closure of the abdominal wall after colorectal surgery. Coll Antropol 35:439–443

    CAS  PubMed  Google Scholar 

  25. Seiler CM, Bruckner T, Diener MK et al (2009) Interrupted or continuous slowly absorbable sutures for closure of primary elective midline abdominal incisions: a multicenter randomized trial (INSECT: ISRCTN24023541). Ann Surg 249:576–582

    Article  PubMed  Google Scholar 

  26. Smith RL, Bohl JK, Mcelearney ST et al (2004) Wound infection after elective colorectal resection. Ann Surg 239:599–605 (discussion 605–597)

    Article  PubMed  PubMed Central  Google Scholar 

  27. Smyth ET, Mcilvenny G, Enstone JE et al (2008) Four country healthcare associated infection prevalence survey 2006: overview of the results. J Hosp Infect 69:230–248

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to M. K. Diener.

Ethics declarations

Interessenkonflikt

P. Heger, F. Pianka, M. K. Diener und A. L. Mihaljevic geben an, dass kein Interessenkonflikt besteht.

Dieser Beitrag beinhaltet keine von den Autoren durchgeführten Studien an Menschen oder Tieren.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Heger, P., Pianka, F., Diener, M.K. et al. Aktuelle Studienlage zum Bauchdeckenverschluss. Chirurg 87, 737–743 (2016). https://doi.org/10.1007/s00104-016-0231-0

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00104-016-0231-0

Schlüsselwörter

Keywords

Navigation