Zusammenfassung
Hintergrund
Initial wurden vornehmlich kleine oberflächliche Leberläsionen laparoskopisch reseziert. Mittlerweile werden in Zentren auch Majorleberresektionen minimalinvasiv durchgeführt. Die Selektion der geeigneten Patienten spielt für die Machbarkeit und den Erfolg des Eingriffs eine zentrale Rolle.
Ziele und Methoden
Diese Arbeit legt die Patientenselektion, Verfahrenswahl und Ergebnisse bei laparoskopischen Leberresektionen auf Basis eines Reviews der aktuellen Literatur dar.
Ergebnisse
Die laparoskopische Leberresektion bietet gegenüber der offenen Resektion deutliche Vorteile hinsichtlich eines reduzierten Blutverlusts, einer verminderten leberspezifischen und Gesamtkomplikationsrate sowie der geringeren Dauer des Krankenhausaufenthalts, ohne die onkologischen Ergebnisse negativ zu beeinflussen.
Schlussfolgerung
Als gut laparoskopisch erreichbar gelten Läsionen in den peripheren Abschnitten der anterolateralen Lebersegmente (Segmente 2, 3, 4b, 5 und 6). Die posterosuperioren Abschnitte (Segmente 1, 4a, 7 und 8) galten zunächst als bedingt geeignet für laparoskopische Resektionen. Jedoch zeigt sich zunehmend, dass auch hier in erfahrenen Zentren sicher und onkologisch radikal minimalinvasiv reseziert werden kann.
Abstract
Background
Initially, mainly superficial liver lesions were resected laparoscopically but now even major resections are performed using a minimally invasive procedure. Careful selection of suitable patients is of key importance.
Aims and methods
This article describes the current state of the art in patient selection and choice of the appropriate laparoscopic technique based on a review of the recent literature. Perioperative and oncological outcome parameters of laparoscopic liver resection are presented.
Results
Laparoscopic liver resection offers significant benefits compared to open liver resection in terms of reduced intraoperative blood loss, reduced overall and liver-specific complications and length of hospital stay without compromising oncological outcomes.
Conclusion
Lesions in the peripheral anterolateral segments (segments 2, 3, 4b, 5 and 6) are particularly suitable for laparoscopic liver resection. Access to the posterosuperior segments 1, 4a, 7 and 8 is more challenging but safe and feasible in experienced centers.
Literatur
Keus F, Gooszen HG, Laarhoven CJ van (2010) Open, small-incision, or laparoscopic cholecystectomy for patients with symptomatic cholecystolithiasis. An overview of Cochrane Hepato-Biliary Group reviews. Cochrane Database Syst Rev CD008318. DOI 10.1002/14651858.CD008318
Fleshman J, Sargent DJ, Green E et al (2007) Laparoscopic colectomy for cancer is not inferior to open surgery based on 5-year data from the COST Study Group trial. Ann Surg 246:655–662. DOI 10.1097/SLA.0b013e318155a762
Gagner M et al (1992) Laparoscopic portal hepatectomy for liver tumors. Surg Endosc 6:99
Chang S, Laurent A, Tayar C et al (2007) Laparoscopy as a routine approach for left lateral sectionectomy. Br J Surg 94:58–63. DOI 10.1002/bjs.5562
Dagher I, O’Rourke N, Geller DA et al (2009) Laparoscopic major hepatectomy: an evolution in standard of care. Ann Surg 250:856–860. DOI 10.1097/SLA.0b013e3181bcaf46
Kirchberg J, Reißfelder C, Weitz J, Koch M (2013) Laparoscopic surgery of liver tumors. Langenbecks Arch Surg 398:931–938. DOI 10.1007/s00423-013-1117-y
Rao A, Rao G, Ahmed I (2012) Laparoscopic or open liver resection? Let systematic review decide it. Am J Surg 204:222–231. DOI 10.1016/j.amjsurg.2011.08.013
Rao AM, Ahmed I (2013) Laparoscopic versus open liver resection for benign and malignant hepatic lesions in adults. Cochrane Database Syst Rev 5:CD010162. DOI 10.1002/14651858.CD010162.pub2
Couinaud C (1999) Liver anatomy: portal (and suprahepatic) or biliary segmentation. Dig Surg 16:459–467
Strasberg SM (2005) Nomenclature of hepatic anatomy and resections: a review of the Brisbane 2000 system. J Hepatobiliary Pancreat Surg 12:351–355. DOI 10.1007/s00534-005-0999-7
Gerges FJ, Kanazi GE, Jabbour-Khoury SI (2006) Anesthesia for laparoscopy: a review. J Clin Anesth 18:67–78. DOI 10.1016/j.jclinane.2005.01.013
Topal B, Fieuws S, Aerts R et al (2008) Laparoscopic versus open liver resection of hepatic neoplasms: comparative analysis of short-term results. Surg Endosc 22:2208–2213. DOI 10.1007/s00464-008-0023-9
Schindl MJ, Redhead DN, Fearon KC et al (2005) The value of residual liver volume as a predictor of hepatic dysfunction and infection after major liver resection. Gut 54:289–296. DOI 10.1136/gut.2004.046524
Schnitzbauer AA, Lang SA, Goessmann H et al (2012) Right portal vein ligation combined with in situ splitting induces rapid left lateral liver lobe hypertrophy enabling 2-staged extended right hepatic resection in small-for-size settings. Ann Surg 255:405–414. DOI 10.1097/SLA.0b013e31824856f5
Buell JF, Cherqui D, Geller DA et al (2009) The international position on laparoscopic liver surgery: the Louisville Statement, 2008. Ann Surg 250:825–830
Ikeda T, Mano Y, Morita K et al (2013) Pure laparoscopic hepatectomy in semiprone position for right hepatic major resection. J Hepatobiliary Pancreat Sci 20:145–150. DOI 10.1007/s00534-012-0558-y
Yoon Y-S et al (2010) Total laparoscopic liver resection for hepatocellular carcinoma located in all segments of the liver. Surg Endosc 24:1630–1637
Mostaedi R, Milosevic Z, Han H-S, Khatri VP (2012) Laparoscopic liver resection: current role and limitations. World J Gastrointest Oncol 4:187–192. DOI 10.4251/wjgo.v4.i8.187
Gurusamy KS, Pamecha V, Sharma D, Davidson BR (2009) Techniques for liver parenchymal transection in liver resection. Cochrane Database Syst Rev CD006880. DOI 10.1002/14651858.CD006880.pub2
Rahbari NN, Koch M, Schmidt T et al (2009) Meta-analysis of the clamp-crushing technique for transection of the parenchyma in elective hepatic resection: back to where we started? Ann Surg Oncol 16:630–639. DOI 10.1245/s10434-008-0266-7
Mirnezami R, Mirnezami AH, Chandrakumaran K et al (2011) Short- and long-term outcomes after laparoscopic and open hepatic resection: systematic review and meta-analysis. HPB (Oxford) 13:295–308. DOI 10.1111/j.1477-2574.2011.00295.x
Parks KR, Kuo Y-H, Davis JM et al (2013) Laparoscopic versus open liver resection: a meta-analysis of long-term outcome. HPB (Oxford) 16:109–118. DOI 10.1111/hpb.12117
Nguyen KT, Laurent A, Dagher I et al (2009) Minimally invasive liver resection for metastatic colorectal cancer: a multi-institutional, international report of safety, feasibility, and early outcomes. Ann Surg 250:842–848. DOI 10.1097/SLA.0b013e3181bc789c
Polignano FM, Quyn AJ, Figueiredo RS de et al (2008) Laparoscopic versus open liver segmentectomy: prospective, case-matched, intention-to-treat analysis of clinical outcomes and cost effectiveness. Surg Endosc 22:2564–2570. DOI 10.1007/s00464-008-0110-y
Cannon RM, Scoggins CR, Callender GG et al (2013) Financial comparison of laparoscopic versus open hepatic resection using deviation-based cost modeling. Ann Surg Oncol 20:2887–2892. DOI 10.1245/s10434-013-2993-7
Dapri G, Dimarco L, Cadière G-B, Donckier V (2012) Initial experience in single-incision transumbilical laparoscopic liver resection: indications, potential benefits, and limitations. HPB Surg 2012:921973. DOI 10.1155/2012/921973
Ho C-M, Wakabayashi G, Nitta H et al (2013) Systematic review of robotic liver resection. Surg Endosc 27:732–739. DOI 10.1007/s00464-012-2547-2
Van Dam RM, Wong-Lun-Hing EM, Breukelen GJ van et al (2012) Open versus laparoscopic left lateral hepatic sectionectomy within an enhanced recovery ERAS® programme (ORANGE II-trial): study protocol for a randomised controlled trial. Trials 13:54. DOI 10.1186/1745-6215-13-54
Vigano L, Laurent A, Tayar C et al (2009) The learning curve in laparoscopic liver resection: improved feasibility and reproducibility. Ann Surg 250:772–782. DOI 10.1097/SLA.0b013e3181bd93b2
Einhaltun ethischer Richtlinien
Interessenkonflikt. J. Kirchberg und J. Weitz geben an, dass kein Interessenkonflikt besteht. Der Beitrag enthält keine Studien an Menschen oder Tieren.
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Kirchberg, J., Weitz, J. Minimalinvasive Chirurgie primärer und sekundärer Lebertumoren. Chirurg 85, 689–695 (2014). https://doi.org/10.1007/s00104-014-2756-4
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DOI: https://doi.org/10.1007/s00104-014-2756-4