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Klinische Studien in der Chirurgie

Auf dem Weg zur evidenzbasierten Chirurgie

Clinical trials in surgery

On the way towards evidence-based surgery

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Zusammenfassung

Das Studienzentrum der Deutschen Gesellschaft für Chirurgie (SDGC) hat die Aufgabe, die klinische Forschung in der Chirurgie nachhaltig zu unterstützen. Besonderer Fokus liegt hierbei auf der Entwicklung und Durchführung von klinischen Studien in Deutschland an Universitätskliniken, aber auch an nichtuniversitären Häusern. Die vorliegende Übersicht skizziert aktuelle Handlungsfelder des SDGC mit Blick in die Zukunft.

Abstract

The Study Centre of the German Surgical Society (SDGC) aims at a sustainable support of clinical trials in surgery. The SDGC focuses especially on the development and conducting of clinical trials in university and non-academic hospitals. This article outlines current fields of action and future perspectives of the SDGC.

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Literatur

  1. Barkun JS, Aronson JK, Feldman LS et al (2009) Evaluation and stages of surgical innovations. Lancet 374:1089–1096

    Article  PubMed  Google Scholar 

  2. Bekelman JE et al (2003) Scope and impact of financial conflicts of interest in biomedical research: a systematic review. JAMA 289:454–465

    Article  PubMed  Google Scholar 

  3. Büchler MW, Diener MK, Weitz J (2011) Scientific evaluation of modern clinical research: we need a new currency! Langenbecks Arch Surg 396:937–939

    Article  PubMed  Google Scholar 

  4. Fink C, Keck T, Rossion I et al (2011) Contribution of the study center of the German Surgical Society to evidence based surgery. Chirurg 82:1109–1115

    Article  PubMed  CAS  Google Scholar 

  5. Diener MK, Bruckner T, Contin P et al (2010) ChroPac-trial: duodenum-preserving pancreatic head resection versus pancreatoduodenectomy for chronic pancreatitis. Trial protocol of a randomised controlled multicentre trial. Trials 11:47

    Article  PubMed  Google Scholar 

  6. Diener MK, Simon T, Buchler MW, Seiler CM (2011) Surgical evaluation and knowledge transfer-methods of clinical research in surgery. Langenbecks Arch Surg [Epub ahead of print]

  7. Diener MK, Seiler CM, Rossion I et al (2011) Efficacy of stapler versus hand-sewn closure after distal pancreatectomy (DISPACT): a randomised, controlled multicentre trial. Lancet 377:1514–1522

    Article  PubMed  Google Scholar 

  8. Diener MK, Wolff RF, Elm E von et al (2009) Can decision making in general surgery be based on evidence? An empirical study of Cochrane Reviews. Surgery 146:444–461

    Article  PubMed  Google Scholar 

  9. Gluud C, Nikolova D (2007) Likely country of origin in publications on randomised controlled trials and controlled clinical trials during the last 60 years. Trials 8:7

    Article  PubMed  Google Scholar 

  10. Heger U, Voss S, Knebel P et al (2011) Prevention of abdominal wound infection (PROUD trial, DRKS00000390): study protocol for a randomized controlled trial. Trials 12:245

    Article  PubMed  Google Scholar 

  11. http://www.consort-statement.org

  12. http://www.wma.net/en/30publications/10policies/b3/17c.pdf

  13. IOM (2009) Conflicts of interest in medical research, education and practice. National Academies Press, Institute of Medicine (IOM), Washington D.C.

  14. Lexchin J, Bero LA, Djulbegovic B, Clark O (2003) Pharmaceutical industry sponsorship and research outcome and quality: systematic review. BMJ 326:1167–1170

    Article  PubMed  Google Scholar 

  15. Neoptolemos JP, Stocken DD, Friess H et al (2004) A randomized trial of chemoradiotherapy and chemotherapy after resection of pancreatic cancer. N Engl J Med 350:1200–1210

    Article  PubMed  CAS  Google Scholar 

  16. Seiler CM, Bruckner T, Diener MK et al (2009) Interrupted or continuous slowly absorbable sutures for closure of primary elective midline abdominal incisions: a multicenter randomized trial (INSECT: ISRCTN24023541). Ann Surg 249:576–582

    Article  PubMed  Google Scholar 

  17. Wente MN, Seiler CM, Uhl W, Büchler MW (2003) Perspectives of evidence-based surgery. Dig Surg 20:263–269

    Article  PubMed  Google Scholar 

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Correspondence to M.K. Diener.

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Diener, M., Knebel, P., Fink, C. et al. Klinische Studien in der Chirurgie. Chirurg 83, 315–318 (2012). https://doi.org/10.1007/s00104-011-2219-0

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  • DOI: https://doi.org/10.1007/s00104-011-2219-0

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