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Therapie der opioidinduzierten Obstipation

Therapy of opioid-induced constipation

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Literatur

  1. Thomas J (2008) Opioid-induced bowel dysfunction. J Pain Symptom Manage 35: 103–113

    Article  PubMed  CAS  Google Scholar 

  2. Reintam A, Parm P, Redlich U, Tooding et al. (2006) Gastrointestinal failure in intensive care: a retrospective clinical study in three different intensive care units in Germany and Estonia. BMC Gastroenterol 6: 19

    Article  PubMed  Google Scholar 

  3. Mostafa SM, Bhandari S, Ritchie G et al. (2003) Constipation and its implications in the critically ill patient. Br J Anaesth 91: 815–819

    Article  PubMed  CAS  Google Scholar 

  4. Berde C, Nurko S (2008) Opioid side effects – mechanism-based therapy. N Engl J Med 358: 2400–2402

    Article  PubMed  CAS  Google Scholar 

  5. Thomas J, Karver S, Cooney GA et al. (2008) Methylnaltrexone for opioid-induced constipation in advanced illness. N Engl J Med 358: 2332–2343

    Article  PubMed  CAS  Google Scholar 

  6. Yuan CS, Foss JF (2000) Oral methylnaltrexone for opioid-induced constipation. JAMA 284: 1383–1384

    Article  PubMed  CAS  Google Scholar 

  7. Yuan CS, Doshan H, Charney MR et al. (2005) Tolerability, gut effects, and pharmacokinetics of methylnaltrexone following repeated intravenous administration in humans. J Clin Pharmacol 45: 538–546

    Article  PubMed  CAS  Google Scholar 

  8. Liu M, Wittbrodt E (2002) Low-dose oral naloxone reverses opioid-induced constipation and analgesia. J Pain Symptom Manage 23: 48–53

    Article  PubMed  Google Scholar 

  9. Reichle FM, Conzen PF (2008) Methylnaltrexone, a new peripheral mu-receptor antagonist for the prevention and treatment of opioid-induced extracerebral side effects. Curr Opin Investig Drugs 9: 90–100

    PubMed  CAS  Google Scholar 

  10. Liu SS, Hodgson PS, Carpenter RL, Fricke JR Jr (2001) ADL 8-2698, a trans-3,4-dimethyl-4-(3-hydroxyphenyl) piperidine, prevents gastrointestinal effects of intravenous morphine without affecting analgesia. Clin Pharmacol Ther 69: 66–71

    Article  PubMed  CAS  Google Scholar 

  11. Spoel JI van der, Schultz MJ, Voort PH van der, Jonge E de (2006) Influence of severity of illness, medication and selective decontamination on defecation. Intensive Care Med 32: 875–880

    Article  PubMed  Google Scholar 

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Chappell, D., Conzen, P. Therapie der opioidinduzierten Obstipation. Anaesthesist 57, 1011–1014 (2008). https://doi.org/10.1007/s00101-008-1420-0

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