Zusammenfassung
Die Transplantation menschlicher Organe ist eine etablierte und meist die einzige lebensrettende Therapie für Patienten im Endstadium eines Organversagens. Derzeit stellt der Mangel an Organen ein großes Problem dar. Die rechtliche Grundlage für eine Transplantation bildet das Transplantationsgesetz (TPG), demzufolge jeder beatmete Patient mit diagnostiziertem Hirntod als potenzieller Organspender in Frage kommt. Im Rahmen des Hirntods kann es zu ausgeprägten Herz-Kreislauf-Reaktionen, Störungen der Thermoregulation, des Wasser- und Elektrolythaushalts, des Endokriniums sowie des Gerinnungssystems kommen. Die organprotektive Therapie beim Spender sowie der Umgang mit dessen Angehörigen stellen besonders hohe Anforderungen an den Intensivmediziner und das Pflegepersonal.
Abstract
For patients with end-stage organ disease transplantation of human organs is a well-established therapy, and in most cases it is the only life-saving one. But the lack of available organs is a big problem. The legal basis in Germany is the transplantation law (TPG). According to this law, every ventilated patient with diagnosed brain death is a potential organ donor. However, brain death may lead to strong reactions in the patient’s cardiovascular system as well as disturbances in thermoregulation, water and electrolyte balance, and the endocrine and haemostatic systems. Thus, protecting the organs of the organ donor and, furthermore, caring for his or her relatives are great challenges for every physician and nurse in the intensive care unit.
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Ein Erratum zu diesem Beitrag ist unter http://dx.doi.org/10.1007/s00101-007-1298-2 zu finden.
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Hömme, R., Neeser, G. Organspende. Anaesthesist 56, 1291–1303 (2007). https://doi.org/10.1007/s00101-007-1284-8
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DOI: https://doi.org/10.1007/s00101-007-1284-8