Abstract
Purpose
The impact of obesity on outcomes has been documented extensively in the elective orthopaedic literature, but little is known about the impact of obesity on outcomes following orthopaedic trauma surgery. Utilizing the ACS-NSQIP database, we sought to investigate the relationship between BMI and perioperative complications in orthopaedic trauma patients.
Methods
53,219 orthopaedic trauma patients were identified using a CPT code search between 2005 and 2013 in the NSQIP database. Patient demographics, and perioperative complications (including minor, major, and total) were collected. Multivariate regression analysis was performed to control for baseline demographics and comorbidities.
Results
Compared with patients of normal weight, underweight patients had significantly greater odds of minor [OR 1.12, 95 % CI (1.0, 1.26), p = 0.04], major [OR 1.20, 95 % CI (1.1, 1.3), p = 0.0009], and total complications [OR 1.18, 95 % CI (1.1, 1.3), p = 0.0003]. Morbidly obese patients had significantly greater odds of major [OR 1.22, 95 % CI (1.0, 1.5), p = 0.023] and total complications [OR 1.18, 95 % CI (1.0, 1.4), p = 0.023] compared to normal weight patients. When wound-related complications were examined independently, obesity was associated with increased odds of superficial [OR 1.67, 95 % CI (1.3, 2.1), p < 0.0001] and deep wound infection [OR 1.52, 95 % CI (1.075, 2.144), p = 0.018], and morbid obesity was associated with increased odds of wound dehiscence [OR 2.29, 95 % CI (1.1, 4.9), p = 0.034] and deep infection [OR 2.51, 95 % CI (1.6, 3.9), p < 0.0001].
Conclusions
Morbidly obese patients have significantly greater odds of wound dehiscence, deep wound infection, major complications, and total complications compared to patients of normal weight. Additionally, BMI under 18.5 is associated with increased odds of minor, major, and total perioperative complications. Interventions aimed at decreasing complication rates should be targeted at these high-risk patient populations on both ends of the BMI spectrum.
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Conflict of interest and source of funding
Author William T. Obremskey (WTO) has done expert testimony in legal matters. The institution of one or more authors (WTO) has received a grant from the Department of Defense. Paul S. Whiting, Gabrielle A. White-Dzuro, Frank R. Avilucea, Ashley C. Dodd, Nikita Lakomkin, Cory A. Collinge, and Manish K. Sethi declare that they have no conflict of interest.
Compliance with ethical requirements
This study was performed in accordance with the relevant regulations of the US Health Insurance Portability and Accountability Act (HIPPA) and the ethical standards of the 1964 Declaration of Helsinki. The protocol was approved by the Vanderbilt Institution Review Board.
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Whiting, P.S., White-Dzuro, G.A., Avilucea, F.R. et al. Body mass index predicts perioperative complications following orthopaedic trauma surgery: an ACS-NSQIP analysis. Eur J Trauma Emerg Surg 43, 255–264 (2017). https://doi.org/10.1007/s00068-016-0642-0
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DOI: https://doi.org/10.1007/s00068-016-0642-0