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Automated IMRT planning in Pinnacle

A study in head-and-neck cancer

Automatisierte IMRT-Planung mit Pinnacle

Eine Studie zu Kopf-Hals-Tumoren

  • Original Article
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Strahlentherapie und Onkologie Aims and scope Submit manuscript

A Correction to this article was published on 27 October 2017

This article has been updated

Abstract

Purpose

This study evaluates the performance and planning efficacy of the Auto-Planning (AP) module in the clinical version of Pinnacle 9.10 (Philips Radiation Oncology Systems, Fitchburg, WI, USA).

Methods and materials

Twenty automated intensity-modulated radiotherapy (IMRT) plans were compared with the original manually planned clinical IMRT plans from patients with oropharyngeal cancer.

Results

Auto-Planning with IMRT offers similar coverage of the planning target volume as the original manually planned clinical plans, as well as better sparing of the contralateral parotid gland, contralateral submandibular gland, larynx, mandible, and brainstem. The mean dose of the contralateral parotid gland and contralateral submandibular gland could be reduced by 2.5 Gy and 1.7 Gy on average. The number of monitor units was reduced with an average of 143.9 (18%). Hands-on planning time was reduced from 1.5–3 h to less than 1 h.

Conclusions

The Auto-Planning module was able to produce clinically acceptable head and neck IMRT plans with consistent quality.

Zusammenfassung

Ziele

Diese Studie untersucht die Leistungsfähigkeit und Planungseffektivität des Auto-Planning-Moduls in der klinischen Version von Pinnacle 9.10 (Philips Radiation Oncology Systems, Fitchburg, WI, USA).

Methoden und Material

Zwanzig automatisch erstellte Pläne für die intensitätsmodulierte Strahlentherapie (IMRT) wurden mit den ursprünglichen manuell erstellten klinischen IMRT-Plänen von Patienten mit Oropharynxkarzinom verglichen.

Ergebnisse

Die automatisch erstellten IMRT-Pläne bieten eine vergleichbare Deckung des Planungszielvolumens (PTV) wie die ursprünglichen, manuell erstellten klinischen Pläne sowie eine verbesserte Schonung der kontralateralen Ohrspeicheldrüse, der kontralateralen Unterkieferspeicheldrüse, des Kehlkopfs, des Unterkiefers und des Hirnstamms. Die mittlere Dosis der kontralateralen Ohr- und kontralateralen Unterkieferspeicheldrüse konnte um durchschnittlich 2,5 bzw. 1,7 Gy reduziert werden. Die Anzahl der Monitoreinheiten wurde im Durchschnitt um 143,9 (18 %) reduziert. Die praktische Planungszeit wurde von 1,5–3 h auf weniger als 1 h minimiert.

Schlussfolgerung

Das Auto-Planning-Modul war in der Lage, klinisch akzeptable Kopf-Hals-IMRT-Pläne mit konsistenter Qualität zu produzieren.

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Change history

  • 27 October 2017

    Correction to:

Abbreviations

AP:

Auto-Planning

CI:

Conformity index

\(D_{2\mathrm{\% }}\) :

Near-maximum dose

\(D_{50\mathrm{\% }}\) :

Median dose

\(D_{98\mathrm{\% }}\) :

Near-minimum dose

DMPO:

Direct machine parameter optimization

DVH:

Dose–volume histogram

HI:

Homogeneity index

IMRT:

Intensity-modulated radiotherapy

MU:

Monitor unit

PTV:

Planning target volume

OAR:

Organ at risk

OVH:

Overlapping volume histogram

SIB:

Simultaneous integrated boost

VMAT:

Volumetric modulated arc therapy

V95% :

Percentage of the target volume that receives at least 95% of the prescribed dose

V95% :

Total volume covered by 95% of the prescribed dose

VPTV95% :

Total volume of PTV covered by 95% of the prescribed dose

VPTV :

Total volume of the PTV

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Funding

This research was sponsored by Philips Healthcare, Fitchburg, WI, USA.

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Authors and Affiliations

  1. Department of Radiation Oncology, Radboud university medical center, Postbox 9101, 6500 HB, Nijmegen, The Netherlands

    J. M. A. M. Kusters PhD, P. G. M van Kollenburg RTT, M. C. Kunze-Busch PhD, M. Wendling PhD, T. Dijkema MD, PhD & J. H. A. M. Kaanders MD, PhD

  2. Philips Radiation Oncology Systems, Philips Healthcare, 53711, Fitchburg, WI, USA

    K. Bzdusek PhD

  3. Philips Innovation Campus, Philips Electronics India Ltd., Bangalore, India

    P. Kumar MSc

Authors
  1. J. M. A. M. Kusters PhD
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  2. K. Bzdusek PhD
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  3. P. Kumar MSc
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  4. P. G. M van Kollenburg RTT
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  5. M. C. Kunze-Busch PhD
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  6. M. Wendling PhD
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  7. T. Dijkema MD, PhD
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  8. J. H. A. M. Kaanders MD, PhD
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Corresponding author

Correspondence to J. M. A. M. Kusters PhD.

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Conflict of interest

J. M. A. M. Kusters, K. Bzdusek, P. Kumar, P. G. M. van Kollenburg, M. C. Kunze-Busch, M. Wendling, T. Dijkema and J. H. A. M. Kaanders declare that they have no competing interests.

Ethical standards

This article does not contain any studies with human participants or animals performed by any of the authors.

Additional information

A correction to this article is available online at https://doi.org/10.1007/s00066-017-1230-x.

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Kusters, J.M.A.M., Bzdusek, K., Kumar, P. et al. Automated IMRT planning in Pinnacle. Strahlenther Onkol 193, 1031–1038 (2017). https://doi.org/10.1007/s00066-017-1187-9

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  • DOI: https://doi.org/10.1007/s00066-017-1187-9

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