Literatur
Barzan D, Maier P, Zeller WJ et al (2010) Overexpression of caveolin-1 in lymphoblastoid TK6 cells enhances proliferation after irradiation with clinically relevant doses. Strahlenther Onkol 186:99–106
Dörr W (1997) Three A’s of repopulation during fractionated irradiation in squamous epithelia: asymmetry loss, acceleration of stem-cell divisions and abortive divisions. Int J Radiat Biol 72:635–643
Dörr W (2003) Oral mucosa: response modification by keratinocyte growth factor. In: Nieder C, Milas L, Ang KK (Hrsg) Biological modification of radiation response. Springer, Berlin, S 113–122
Dörr W (2009) Time factors in normal tissue responses to irradiation. In: Joiner M, Van der Kogel A (Hrsg) Basic clinical radiobiology, 4th Aufl. Hodder Arnold, London, S 149–157
Dörr W (2009) Pathogenesis of normal tissue side effects. In: Joiner M, Van der Kogel A (Hrsg) Basic clinical radiobiology, 4th Aufl. Hodder Arnold, London, S 169–190
Dörr W (2009) Biological response modifiers: normal tissues. In: Joiner M, Van der Kogel A (Hrsg) Basic clinical radiobiology, 4th Aufl. Hodder Arnold, London, S 301–315
Dörr E, Dörr W, Herrmann T (2007) Dexpanthenol vs. Wasser zur Mundspülung bei strahleninduzierter Mucositis enoralis – Ergebnisse einer randomisierten, einfach-blinden Untersuchung an 366 Patienten mit Tumoren im Kopf-Hals-Bereich. Strahlenther Onkol 1:9–10 (183 Sondernr)
Dörr W, Gabriel P, Haagen J et al (2009) Modulation of oral mucositis during fractionated irradiation by mobilisation of bone marrow stem cells: preclinical studies. Oral Oncol (Suppl 3):233
Dörr W, Gabriel P, Siegemund A et al (2005) Modification of oral mucositis (mouse) by treatment with adult stem cells. Supp Care Cancer 13:441
Dörr W, Schlichting S, Bray MA et al (2005) Effects of dexpanthenol with or without Aloe vera extract on radiation-induced oral mucositis: preclinical studies. Int J Radiat Biol 81:243–250
Dörr W, Van der Kogel AJ (2009) The volume effect in radiotherapy. In: Joiner M, Van der Kogel A (Hrsg) Basic clinical radiobiology, 4th Aufl. Hodder Arnold, London, S 191–206
Fleischer G, Dörr W (2006) Amelioration of acute oral mucositis (mouse) by intravenous or subcutaneous administration of Amifostine. Strahlenther Onkol 182:367–375
Gehrisch A, Dörr W (2007) Effects of systemic or topical administration of sodium selenite on early radiation effects in mouse oral mucosa. Strahlenther Onkol 183:36–42
Haagen J, Krohn H, Röllig S et al (2009) Effect of selective inhibitors of inflammation on oral mucositis: preclinical studies. Radiother Oncol 92:472–476
Haagen J, Schmidt M, Siegemund A et al (2008) Modification of radiation-induced oral mucositis (mouse) by treatment with adult mesenchymal stem cells. Radiother Oncol 88(Suppl. 2):S92
Henke M, Alfonsi M, Foa P et al (2011) Palifermin decreases severe oral mucositis of patients undergoing postoperative radiochemotherapy for head and neck cancer: a randomized, placebo-controlled trial. J Clin Oncol 29:2815–2820
Herrmann T, Baumann M, Dörr W (2006) Klinische Strahlenbiologie – kurz und bündig, 4 Aufl. Elsevier, München
Hille A, Rave-Fränk M, Christiansen H et al (2009) Faecal calprotectin and lactoferrin values during irradiation of prostate cancer correlate with chronic radiation proctitis: results of a prospective study. Scand J Gastroenterol 44:5939–5946
Jaal J, Dörr W (2006) Radiation induced late damage to the barrier function of small blood vessels in mouse bladder. J Urol 176:2696–2700
Jaal J, Dörr W (2007) Effect of recombinant Human Keratinocyte Growth Factor (rHuKGF, Palifermin) on radiation-induced mouse urinary bladder dysfunction. Int J Radiat Oncol Biol Phys 69:528–533
Jaal J, Richter C, Dörr W (2010) Effect of recombinant human keratinocyte growth factor (Δ23rHuKGF, Palifermin) on inflammatory and immune changes in mouse tongue during fractionated irradiation. Int J Radiat Biol 86:860–866
Kertesz T, Herrmann MK, Zapf A et al (2009) Effect of a prostaglandin – given rectally for prevention of radiation-induced acute proctitis – on late rectal toxicity. Results of a phase III randomized, placebo-controlled, double-blind study. Strahlenther Onkol 185:596–602
Kuschel M, Siegemund A, Noack R et al (2006) Modifikation der Strahlenreaktion der Mundschleimhaut (Maus) durch Transplantation von adulten hämatopoetischen Stammzellen. Strahlenther Onkol 1:8–9 (182 Sondernr)
Maier P, Veldwijk MR, Wenz F (2011) Radioprotective gene therapy. Expert Opin Biol Ther 11:1135–1151
Maier P, Herskind C, Barzan D et al (2010) SNAI2 as a novel radioprotector of normal tissue by gene transfer using a lentiviral bicistronic SIN vector. Radiat Res 173:612–619
Rodemann HP, Bamberg M (1995) Cellular basis of radiation-induced fibrosis. Radiother Oncol 35:83–90
Rübe CE, Dong X, Kühne M et al (2008) DNA double-strand break rejoining in complex normal tissues. Int J Radiat Oncol Biol Phys 72:1180–1187
Veldwijk MR, Herskind C, Sellner L et al (2009) Normal-tissue radioprotection by overexpression of copper-zinc and manganese superoxide dismutase genes. Strahlenther Onkol 185:517–523
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Wolfgang Dörr und Carsten Herskind haben gleichermaßen zur Arbeit beigetragen.
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Dörr, W., Herskind, C. Strahlenbiologie der Normalgewebe. Strahlenther Onkol 188 (Suppl 3), 295–298 (2012). https://doi.org/10.1007/s00066-012-0202-4
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DOI: https://doi.org/10.1007/s00066-012-0202-4