Abstract.
Auxin response factors or ARFs are a recently discovered family of transcription factors that bind with specificity to auxin response elements (AuxREs) in promoters of primary or early auxin-responsive genes. ARFs have an amino-terminal DNA-binding domain related to the carboxyl-terminal DNA-binding domain in the maize transactivator VIVIPAROUS1. All but one ARF identified to date contain a carboxyl-terminal protein-protein interaction domain that forms a putative amphipathic α-helix. A similar carboxyl-terminal protein-protein interaction domain is found in the Aux/IAA class of auxin-inducible proteins. Some ARFs contain transcriptional activation domains, while others contain repression domains. ARFs appear to play a pivotal role in auxin-regulated gene expression of primary response genes.
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Received 28 January 1998; received after revision 30 March 1998; accepted 30 March 1998
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Guilfoyle, T., Ulmasov, T. & Hagen, G. The ARF family of transcription factors and their role in plant hormone-responsive transcription. CMLS, Cell. Mol. Life Sci. 54, 619–627 (1998). https://doi.org/10.1007/s000180050190
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DOI: https://doi.org/10.1007/s000180050190