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Determination of lead and cadmium contents in lipstick and their potential health risks to consumers

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Abstract

In Ghana, a complete profile of heavy metals in lipstick products is lacking. Therefore, this study aimed to assess the level of some toxic metals in lipstick sold at different markets and shopping malls in Kumasi Metropolis. Twenty lipstick brands were analysed. The lipstick was chemically digested and then analysed for lead (Pb) and cadmium (Cd) using atomic absorption spectroscopy (model 210 VGP). The concentrations of Pb and Cd in lipsticks ranged from 0.20 ± 0.00 to 36.70 ± 0.26, and 1.83 ± 0.06 to 412.23 ± 0.40 mg kg−1, respectively. The actual Pb concentration measured in 18 lipstick samples was far below the recommended limits of the United State Food and Drug Administration (20 mg kg−1), Ghana Standards Authority (1 mg kg−1) and Health Canada (10 mg kg−1). The Cd concentration in 19 lipsticks was above the Health Canada threshold for impurities, indicating a potential toxicological effect for lipstick users. The hazard quotient for Cd in almost all the lipstick samples, except sample C12 were above 1, indicating adverse non-carcinogenic health risk exposure to Cd via the lipsticks ingestion. Thus, the continuous usage of these brands of lipsticks can pose a high risk of Cd on human health. Therefore, quality control is recommended to check lipstick products imported into the country. Similarly, regular monitoring of other heavy metal containing components and chemicals used in the manufacture of cosmetics products, which may cause health risks to consumers should be ensured.

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References

  • Ackah M (2015) Status of some metals contained in imported nail polish and lipsticks on the Ghanaian market. Proc Int Acad Ecol Environ Sci 5:142–147

    CAS  Google Scholar 

  • Agorku ES, Kwaansa-Ansah EE, Voegborlo RB, Amegbletor P, Opoku F (2016) Mercury and hydroquinone content of skin toning creams and cosmetic soaps, and the potential risks to the health of Ghanaian women. SpringerPlus 5:1–5

    Article  CAS  Google Scholar 

  • Al-Saleh I, Al-Enazi S (2011) Trace metals in lipsticks. Toxicol Environ Chem 93:1149–1165

    Article  CAS  Google Scholar 

  • Al-Saleh I, Al-Enazi S, Shinwari N (2009) Assessment of lead in cosmetic products. Regul Toxicol Pharmacol 54:105–113

    Article  CAS  Google Scholar 

  • Amartey E, Asumadu-Sakyi A, Adjei C, Quashie F, Duodu G, Bentil N (2011) Determination of heavy metals concentration in hair Pomades on the Ghanaian market using atomic absorption spectrometry technique. Br J Pharmacol Toxicol 2:192–198

    CAS  Google Scholar 

  • Amponsah D, Sebiawu GE, Voegborlo R (2014) Determination of amount of mercury in some selected skin-lightening creams sold in the Ghanaian market. Int J Eng 3:344–350

    Google Scholar 

  • Angeli JK, Pereira CAC, de Oliveira Faria T, Stefanon I, Padilha AS, Vassallo DV (2013) Cadmium exposure induces vascular injury due to endothelial oxidative stress: the role of local angiotensin II and COX-2. Free Radic Biol Med 65:838–848

    Article  CAS  Google Scholar 

  • Atz VL, Pozebon D (2009) Graphite furnace atomic absorption spectrometry (GFAAS) methodology for trace element determination in eye shadow and lipstick. At Spectrosc 30:82–91

    CAS  Google Scholar 

  • Batista ÉF, Augusto AdS, Pereira-Filho ER (2016) Chemometric evaluation of Cd Co, Cr, Cu, Ni (inductively coupled plasma optical emission spectrometry) and Pb (graphite furnace atomic absorption spectrometry) concentrations in lipstick samples intended to be used by adults and children. Talanta 150:206–212

    Article  CAS  Google Scholar 

  • Becker LC et al (2013) Safety assessment of borosilicate glasses as used in cosmetics. Int J Toxicol 32:65S–72S

    Article  Google Scholar 

  • Bocca B, Pino A, Alimonti A, Forte G (2014) Toxic metals contained in cosmetics: a status report. Regul Toxicol Pharmacol 68:447–467

    Article  CAS  Google Scholar 

  • Chauhan AS, Bhadauria R, Singh AK, Lodhi SS, Chaturvedi DK, Tomar VS (2010) Determination of lead and cadmium in cosmetic products. J Chem Pharm Res 2:92–97

    CAS  Google Scholar 

  • Davies RF, Johnston GA (2011) New and emerging cosmetic allergens. Clin Dermatol 29:311–315

    Article  Google Scholar 

  • Fiume MM et al (2013) Safety assessment of decyl glucoside and other alkyl glucosides as used in cosmetics. Int J Toxicol 32:22S–48S

    Article  CAS  Google Scholar 

  • Gardner P, Bertino M, Weimer R, Hazelrigg E (2013) Analysis of lipsticks using Raman spectroscopy. Forensic Sci Int 232:67–72

    Article  CAS  Google Scholar 

  • Ghana Standards Board (2012) Food, chemistry and material standards, 3rd edn. Ghana Standards Board, Accra

    Google Scholar 

  • Gondal MA, Seddigi ZS, Nasr MM, Gondal B (2010) Spectroscopic detection of health hazardous contaminants in lipstick using Laser Induced Breakdown Spectroscopy. J Hazard Mater 175:726–732

    Article  CAS  Google Scholar 

  • Gunduz S, Akman S (2013) Investigation of lead contents in lipsticks by solid sampling high resolution continuum source electrothermal atomic absorption spectrometry. Regul Toxicol Pharmacol 65:34–37

    Article  CAS  Google Scholar 

  • Health Canada (2012) Guidance on heavy metal impurities in cosmetics. Health Canada, Ottawa

    Google Scholar 

  • Johnson W et al (2013) Safety assessment of alkyl glyceryl ethers as used in cosmetics. Int J Toxicol 32:5S–21S

    Article  CAS  Google Scholar 

  • Khan N et al (2013) Method validation for simultaneous determination of chromium, molybdenum and selenium in infant formulas by ICP-OES and ICP-MS. Food Chem 141:3566–3570

    Article  CAS  Google Scholar 

  • Lilley S, Florence T, Stauber J (1988) The use of sweat to monitor lead absorption through the skin. Sci Total Environ 76:267–278

    Article  CAS  Google Scholar 

  • Liu S, Hammond SK, Rojas-Cheatham A (2013) Concentrations and potential health risks of metals in lip products. Environ Health Perspect 121:705–710

    Article  Google Scholar 

  • Loretz L et al (2005) Exposure data for cosmetic products: lipstick, body lotion, and face cream. Food Chem Toxicol 43:279–291

    Article  CAS  Google Scholar 

  • Loretz L et al (2008) Exposure data for cosmetic products: facial cleanser, hair conditioner, and eye shadow. Food Chem Toxicol 46:1516–1524

    Article  CAS  Google Scholar 

  • Lu Y, Yuan T, Wang W, Kannan K (2011) Concentrations and assessment of exposure to siloxanes and synthetic musks in personal care products from China. Environ Pollut 159:3522–3528

    Article  CAS  Google Scholar 

  • Mandel JS et al (1995) International renal-cell cancer study. IV. Occupation. Int J Cancer 61:601–605

    Article  CAS  Google Scholar 

  • Material safety data sheet (2012) Kings Mountain Mica. http://www.dar–technic.com/doc/MicaMSDS.pdf. Accessed 10 Oct 2017

  • Nnorom I, Igwe J, Oji-Nnorom C (2005) Trace metal contents of facial (make-up) cosmetics commonly used in Nigeria. Afr J Biotechnol 4:1133–1138

    CAS  Google Scholar 

  • Nohynek GJ, Antignac E, Re T, Toutain H (2010) Safety assessment of personal care products/cosmetics and their ingredients. Toxicol Appl Pharmacol 243:239–259

    Article  CAS  Google Scholar 

  • Okamoto M, Kanda M, Matsumoto I, Miya Y (1971) Fast analysis of trace amounts of lead in cosmetics by atomic absorption spectrophotometry. J Soc Cosmet Chem 22:589–598

    CAS  Google Scholar 

  • Oluremi O, Oluyemi E (2014) Lipsticks and nail polishes: potential sources of heavy metal in human body. Int J Pharm Res Allied Sci 3:45–51

    Google Scholar 

  • Piccinini P, Piecha M, Torrent SF (2013) European survey on the content of lead in lip products. J Pharm Biomed Anal 76:225–233

    Article  CAS  Google Scholar 

  • Resano M, García-Ruiz E (2011) High-resolution continuum source graphite furnace atomic absorption spectrometry: is it as good as it sounds? A critical review. Anal Bioanal Chem 399:323–330

    Article  CAS  Google Scholar 

  • Sainio EL, Jolanki R, Hakala E, Kanerva L (2000) Metals and arsenic in eye shadows. Contact Dermat 42:5–10

    Article  CAS  Google Scholar 

  • Schaffer SE (2007) Reading our lips: the history of lipstick regulation in Western seats of power. Food Drug Cosmet Law J 62:165–225

    Google Scholar 

  • Soares AR, Nascentes CC (2013) Development of a simple method for the determination of lead in lipstick using alkaline solubilization and graphite furnace atomic absorption spectrometry. Talanta 105:272–277

    Article  CAS  Google Scholar 

  • The SCCP’s notes of guidance for the testing of cosmetic ingredients and their safety evaluation (2006). http://ec.europa.eu/health/scientific_committees/consumer_safety/docs/sccs_s_004.pdf. Accessed 9 Oct 2017

  • Tomankova K et al (2011) In vitro cytotoxicity and phototoxicity study of cosmetics colorants. Toxicol In Vitro 25:1242–1250

    Article  CAS  Google Scholar 

  • Ullah H et al (2017) Comparative study of heavy metals content in cosmetic products of different countries marketed in Khyber Pakhtunkhwa, Pakistan. Arab J Chem 10:10–18

    Article  CAS  Google Scholar 

  • Usepa IRIS (2011) Integrated risk information system. Environmental protection agency region I. United State Environmental Protection Agency, Washington, DC

    Google Scholar 

  • USFDA (2013) Addressing lead at superfund sites. Information for risk assessors. USEPA, Washington, DC

    Google Scholar 

  • Valet B, Mayor M, Fitoussi F, Capellier R, Dormoy M, Ginestar J (2007) Colouring agents in cosmetic products (excluding hair dyes): types of decorative cosmetic products. In: Salvador A, Chisvert A (eds) Analysis of cosmetic products, vol 1. Elsevier BV, Cambridge

    Google Scholar 

  • Voegborlo R, Voegborlo S, Buabeng-Acheampong B, Zogli E (2008) Total mercury content of skin toning creams and the potential risk to the health of women in Ghana. J Sci Technol 28:88–96

    Google Scholar 

  • Volpe M, Nazzaro M, Coppola R, Rapuano F, Aquino R (2012) Determination and assessments of selected heavy metals in eye shadow cosmetics from China, Italy, and USA. Microchem J 101:65–69

    Article  CAS  Google Scholar 

  • Waalkes M, Misra R, Chang L (1996) Cadmium carcinogenicity and genotoxicity, in toxicology of metals. CRC Press, Taylor & Francis Group, Boca Raton

    Google Scholar 

  • Zakaria A, Ho YB (2015) Heavy metals contamination in lipsticks and their associated health risks to lipstick consumers. Regul Toxicol Pharmacol 73:191–195

    Article  CAS  Google Scholar 

Download references

Acknowledgements

The Researchers are grateful to the Department of Chemistry of the Kwame Nkrumah University of Science and Technology for the use of its facilities for this study.

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  1. Department of Chemistry, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana

    Marian Asantewah Nkansah, Emmanuel Owusu-Afriyie & Francis Opoku

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  1. Marian Asantewah Nkansah
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  2. Emmanuel Owusu-Afriyie
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  3. Francis Opoku
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Correspondence to Marian Asantewah Nkansah.

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Nkansah, M.A., Owusu-Afriyie, E. & Opoku, F. Determination of lead and cadmium contents in lipstick and their potential health risks to consumers. J Consum Prot Food Saf 13, 367–373 (2018). https://doi.org/10.1007/s00003-018-1180-y

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  • DOI: https://doi.org/10.1007/s00003-018-1180-y

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