Abstract
Certain steroids and triterpenoids isolated from diverse plant families were known to possess anti-inflammatory activity. In the course of finding new anti-inflammatory natural products, some steroidal and triterpenoid saponins were isolated and evaluated for their anti-inflammatory activity usingin vivo mouse ear edema test. At the oral dose of 100 mg/kg, several steroidal saponins and triterpenoid saponins such as hederagenin glycosides showed significant inhibition of ear edema (20∼37% inhibition), though less potent than indomethacin and hydrocortisone.
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Kim, S.Y., Son, K.H., Chang, H.W. et al. Inhibition of mouse ear edema by steroidal and triterpenoid saponins. Arch Pharm Res 22, 313–316 (1999). https://doi.org/10.1007/BF02976370
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DOI: https://doi.org/10.1007/BF02976370