Abstract
A case of posttraumatic stress disorder is described in which a favorable response to the anticonvulsants carbemazepine and sodium valproate occurred. The literature on the use of anticonvulsants in this disorder is reviewed.
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References
American Psychiatric Association (1994). Practice guide-lines for the treatment of patients with bipolar disorder.American Journal of Psychiatry 151(Suppl.), 5–14.
Archibald, H., & Tuddenham, R. (1965). Persistent stress reactions after combat: A 20 year follow up.Archives of General Psychiatry, 22 475–481.
Friedman, M. (1988) Toward rational pharmacotherapy for post traumatic stress disorder.American Journal of Psychiatry, 145 281–285.
Fesler, F. (1991). Valproate in combat related post traumatic stress disorder.Journal of Clinical Psychiatry, 52 361–364.
Horowitz, M., Wilner, N., & Kaltreider, N. (1980). Signs and symptoms of post traumatic stress disorder.Archives of General Psychiatry, 37 85–92.
Keck, P., McElroy, M., & Friedman, L. (1992). Valproate and carbemazepine in the treatment of panic and posttraumatic stress disorders, withdrawal states and behavioural dyscontrol syndromes.Journal of Clinical Psychopharmacology, 12(Suppl. 1), 36–41.
Klein, E. Colin, E., Stolk, J., & Lenox R. (1994). Alprazolam withdrawal in patients with panic and generalized anxiety disorder: Vulnerability, and effect of carbemazepine.American Journal of Psychiatry, 151 1760–1765.
Lipper, S., Davidson, J., Grady, T., Edinger, J., Hammett, E., Mahorney, S., & Cavenar, J. (1986). Preliminary study of carbemazepine in post traumatic stress disorder.Psychosomatics, 27 849–853.
McFarlane A., & Papay P. (1992). Multiple diagnoses in post traumatic stress disorder in the victims of a natural disaster.Journal of Nervous and Mental Disease, 180 498–504.
Post, R., Weiss, S., & Chuang, D. (1992). Mechanisms of action of anticonvulsants in affective disorders.Journal of Clinical Psychopharmacology, 12(Suppl. 1), 23–35.
Rall, T., & Schleiffer, L. (1990). Drugs effective in the epilepsies. In A. G. Gilman, T. W. Rall, A. S. Nies, & P. Taylor (Eds.)The pharmacological basis of therapeutics (pp. 436–462). New York: Pergamon.
Schweitzer, E., Rickels, K., Case, W., & Greenblatt, D. (1991). Carbemazepine treatment in patients discontinuing long term benzodiazepine treatment.Archives of General Psychiatry, 48 448–452.
Silver, J., Sandberg, D., & Hales, R. (1990). New approaches in the pharmacology of posttraumatic stress disorder.Journal of Clinical Psychiatry, 51(Suppl. 10), 33–38.
Southwick, S., Bremner, D., Krystal, J., & Charney, D. (1994). Psychobiologic research in PTSD.Psychiatric Clinics of North America, 17(2), 409–423.
Sutherland, S., & Davidson, J. (1994). Pharmacotherapy for posttraumatic stress disorder.Psychiatric Clinics of North America, 17(2), 409–423.
van der Kolk, B., Greenberg, M., & Boyd, H. (1985). Inescapable shock, neurotransmitters and addiction to trauma: Toward a psychobiology of Posttraumatic stress.Biological Psychiatry, 20 314–325.
Wolff, M., Alavi, A., & Mosnaim, A. S. (1988). PTSD in Vietnam veterans. Clinical and EEG findings: Possible therapeutic effects of carbemazepine.Biological Psychiatry, 23 642–644.
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Ford, N. The use of anticonvulsants in posttraumatic stress disorder: Case study and overview. J Trauma Stress 9, 857–863 (1996). https://doi.org/10.1007/BF02104107
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DOI: https://doi.org/10.1007/BF02104107