Skip to main content
Log in

A newly developed X-ray transparent ameroid constrictor for study on progression of gradual coronary stenosis

Ein neuentwickelter röntgentransparenter Ameroid-Konstriktor für Untersuchungen über abgestufte Koronarstenosierung

  • Original Contributions
  • Published:
Basic Research in Cardiology Aims and scope Submit manuscript

Summary

For the experimental studies on chronic coronary stenosis, an ameroid constrictor was modified to facilitate serial cineangiographic evaluation of the degree of arterial narrowing. A radiolucent plastic ring instead of a stainless frame was used to prevent outward swelling of the ameroid material.

Coronary cineangiography was performed 10, 20 and 30 days after the implantation of the modified ameroid constrictor on the left circumflex coronary artery (LCX), which could prove the progressive coronary stenosis of 57, 78 and 88% on the respective days. Collateral channels from the anterior descending branch of the left coronary artery to the LCX were demonstrated angiographically in 5 out of the 6 dogs on the 30th day.

Zusammenfassung

Für das experimentelle Studium chronischer Koronarstenosen wurde ein Ameroid-Konstriktor modifiziert, um die Beurteilung des Einengungsgrades aufgrund cineangiographischer Serienuntersuchungen zu erleichtern. Um eine Schwellung des Ameroid-Materials nach außen zu verhindern, wurde — anstelle eines Metallrahmens — ein strahlendruchlässiger Plastikring benutzt.

10, 20 und 30 Tage nach der Implantation des Ameroid-Konstriktors am R. circumflexus der linken Koronararterie wurde eine Koronarangiographie vorgenommen, wobei an den betreffenden Tagen eine fortschreitente Koronareinengung von 57, 78 bzw. 88% nachgewiesen wurde. Bei 5 von 6 Hunden ließen sich am 30. Tag Kollateral-Gefäße vom R. interventr. ant. zum R. circumflexus der linken Koronararterie demonstrieren.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Litvak, J., L. S. Siderides, A. M. Vineberg: The experimental production of coronary artery insufficiency and occlusion. Amer. Heart J.53, 505 (1957).

    Article  PubMed  Google Scholar 

  2. Schaper, W.: The collateral circulation of the heart; Coronary artery occlusion in animals, p. 19 (Amsterdam, 1971).

  3. Schwarz, F., W. Flameng, K. Thiedemann, W. Schaper, M. Schlepper: Effect of coronary stenosis on myocardial function, ultrastructure and aortocoronary bypass graft hemodynamics. Amer. J. Cardiol.42, 193 (1978).

    PubMed  Google Scholar 

  4. Gould, K. L.: Assessment of coronary stenosis with myocardial perfusion imaging during pharmacologic coronary vasodilation. IV. Limits of detection of stenosis with idealized experimental cross-sectional myocardial imaging. Amer. J. Cardiol.42, 761 (1978).

    PubMed  Google Scholar 

  5. Nakamura, M., A. Mitsutake, H. Matsuguchi, Y. Kikuchi, A. Takeshita, O. Nakagaki, Y. Nose, A. Kuroiwa: Effects of collateral circulation on regional myocardial blood flow and left ventricular wall motion. (A preliminary note.) Basic Res. Cardiol.72, 492 (1977).

    PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Additional information

With 4 figures and 1 table

This project was supported in parts by grants from Education Ministry of Japan (No. 344044) and the Japan Heart Foundation Research for 1978. Part of this study was presented at the Annual Meeting of Japanese College of Argiology, Tokyo 1978, Japan.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Inou, T., Tomoike, T., Watanabe, K. et al. A newly developed X-ray transparent ameroid constrictor for study on progression of gradual coronary stenosis. Basic Res Cardiol 75, 537–543 (1980). https://doi.org/10.1007/BF01907835

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01907835

Keywords

Navigation