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Results of R0 surgery with D2 lymphadenectomy for the treatment of localised gastric cancer

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Abstract

Introduction

Surgical excision is the best therapeutic option for gastric cancer, provided it is performed with curative intent as R0 surgery. And, according to many authors, D2 lymphadenectomy may be performed with acceptable morbidity and mortality rates.

Materials and methods

A prospective study was conducted on a series of 126 consecutive cases of gastric cancer treated with gastrectomy and D2 lymphadenectomy. A R0 resection was done in 99 cases (78.6%).

Results

Total gastrectomy was performed in 70 patients and subtotal gastrectomy in 29. The mean number of lymph nodes removed was 32.5 per patient. Suture dehiscence occurred in 3 patients (in one of them in the esophago-jejunal anastomosis). Hospital mortality was 2%. Twenty-six recurrences were detected after a median follow-up of 73.6 months. Five-year actuarial survival was 65%. Five-year survival of patients with positive lymph nodes at the N2 level was 26.5%.

Conclusions

Gastrectomy with D2 lymphadenectomy may be performed with low morbidity and mortality. R0 resection allows acceptable survival rates to be achieved. There is even a group of patients with invaded lymph nodes at the N2 level surviving at 5 years. It appears to be very important that this surgery is performed by specialised surgeons.

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Authors and Affiliations

  1. Esophago-gastric Unit Department of General Surgery, Hospital Universitario Virgen del Camino, C/ Irunlarrea, 3 ES-31008, Pamplona, Navarra, Spain

    Álvaro Díaz de Liaño, Concepción Yárnoz, Cristina Artieda, Alicia Artajona & Héctor Ortiz

  2. Department of General Surgery, Hospital Central Instituto de Previsión Social, Asunción, Paraguay

    Rubén Aguilar

  3. Surgical Clinic “F”, Hospital de Clínicas, Montevideo, Uruguay

    Sherbourne Viana

Authors
  1. Álvaro Díaz de Liaño
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  2. Concepción Yárnoz
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  3. Cristina Artieda
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  4. Rubén Aguilar
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  5. Sherbourne Viana
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  6. Alicia Artajona
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  7. Héctor Ortiz
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Correspondence to Álvaro Díaz de Liaño.

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Díaz de Liaño, Á., Yárnoz, C., Artieda, C. et al. Results of R0 surgery with D2 lymphadenectomy for the treatment of localised gastric cancer. Clin Transl Oncol 11, 178–182 (2009). https://doi.org/10.1007/S12094-009-0335-9

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  • DOI: https://doi.org/10.1007/S12094-009-0335-9

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