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Hyphenation of high-performance liquid chromatography (HPLC) and other chromatographic techniques (SFC, GPC, GC, CE) with nuclear magnetic resonance (NMR): A review

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Abstract.

 The development of the hyphenation of high-performance liquid chromatography (HPLC) and other chromatographic methods (supercritical fluid chromato-graphy (SFC), gel-permeation chromatography (GPC), gas chromatography (GC) and capillary electrophoresis (CE)) with nuclear magnetic resonance (NMR) is reviewed. The focus is not only on application (e.g. pharmaceutical chemistry, food chemistry, polymer analysis, fuel chemistry), but also on technical improvements (e.g. flow rate, flow cell, probe, solvent suppression). The increasing importance and overwhelming analytical possibilities of on-line coupling of HPLC with NMR is demonstrated. The literature up to March 1995 is considered.

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Authors and Affiliations

  1. Commission of the European Communities, Joint Research Centre, Environment Institute, T.P. 740, I-21020 Ispra (VA), Italy, , , , , , IT

    Siegfried A. Korhammer & Alexander Bernreuther

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  1. Siegfried A. Korhammer
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  2. Alexander Bernreuther
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Received: 2 March 1995/Revised: 22 April 1995/Accepted: 27 April 1995

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ID="*" Internationales Hochschulinstitut Zittau, Markt 23, D-02763 Zittau, Germany

Acknowledgements. The authors are grateful for grants from the Commission of the European Communities. They thank Manfred Spraul and Martin Hofmann (Bruker Analytische Meßtechnik, Germany) for comments on the manuscript.

Dedicated to the memory of Hilmar Spiesecke

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Correspondence to: S.A. Korhammer

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Korhammer, S., Bernreuther, A. Hyphenation of high-performance liquid chromatography (HPLC) and other chromatographic techniques (SFC, GPC, GC, CE) with nuclear magnetic resonance (NMR): A review. Fresenius J Anal Chem 354, 131–135 (1996). https://doi.org/10.1007/PL00012706

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  • DOI: https://doi.org/10.1007/PL00012706

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