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Reliability and reproducibility of brain tissue volumetry from segmented MR scans

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European Archives of Psychiatry and Clinical Neuroscience Aims and scope Submit manuscript

Abstract

Reliable measurement of different tissue volumes in the living brain is of great importance for human brain research. In this article, we report on the inter- and intraoperator reliability and scan-rescan reproducibility of segmented intracranial tissue volumes from MR images using the image analysis software suite BRAINS. The absolute data of tissue volume measurements are also presented. The reliability and consistency of the measurements of the segmented volumes were excellent. The segmentation is robust and rapid and the volume measurements are plausible and suitable for quantitative studies in clinical brain research.

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Authors and Affiliations

  1. Dept. Clinical Neuroscience, Human Brain Informatics, Psychiatry Section, Karolinska Institutet and Hospital, 17176 Stockholm, Sweden, Tel.: +46-8/51 77 17 58, Fax: +46-8/51 77 17 17, E-Mail: Ingrid.Agartz@cns.ki.se, , , , , , SE

    Ingrid Agartz, Gaku Okuguwa, Mikael Nordström & Göran Sedvall

  2. Dept. Clinical Neuroscience, MR Research Center, Karolinska Institutet and Hospital, 17176 Stockholm, Sweden, , , , , , SE

    Dan Greitz

  3. Mental Health Clinic and Research Center, University of Iowa Hospitals and Clinics, College of Medicine, Iowa City, IA, USA, , , , , , US

    Vincent Magnotta

Authors
  1. Ingrid Agartz
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  2. Gaku Okuguwa
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  3. Mikael Nordström
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  4. Dan Greitz
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  5. Vincent Magnotta
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  6. Göran Sedvall
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Additional information

Received: 24 April 2001 / Accepted: 24 September 2001

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Agartz, I., Okuguwa, G., Nordström, M. et al. Reliability and reproducibility of brain tissue volumetry from segmented MR scans. European Archives of Psychiatry and Clinical Neurosciences 251, 255–261 (2001). https://doi.org/10.1007/PL00007542

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  • DOI: https://doi.org/10.1007/PL00007542

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