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Lymphoma of the thyroid mimicking thyroiditis in a patient with the acquired immune deficiency syndrome

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Abstract

A 35-year-old man with AIDS and a history of a remission from the lymphoma of the right tonsil (previously treated with chemotherapy and radiation) presented with a variety of clinical, laboratory and radiological findings strongly suggestive of subacute thyroiditis. Fine needle aspiration biopsy failed to establish the tissue diagnosis. Pathological examination of the thyroid tissue obtained during an open surgical biopsy revealed a lymphoma. Appropriate chemotherapy produced a rapid clinical and laboratory improvement manifested by the reduction of the goiter and restoration of a euthyroid state. Hypothyroidism subsequently developed, but therapy with thyroid hormone resulted in a rapid normalization of thyroid function tests. The patient expired because of AIDS-related complications.

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References

  1. Grinspoon S.K., Bilezikian J.P. HIV Disease and the endocrine system. N. Engl. J. Med. 327: 1360, 1992.

    Article  PubMed  CAS  Google Scholar 

  2. Poretsky L., Maran A., Zumoff B. Endocrinologic and metabolic manifestations of the acquired immunodeficiency syndrome. Mt. Sinai J Med. 57: 236, 1990.

    PubMed  CAS  Google Scholar 

  3. LoPresti J.S., Fired J.C., Spencer C.A., Nicoloff J.T. Unique alterations of thyroid hormone indices in the acquired immunodeficiency syndrome (AIDS). Ann Intern Med. 100: 970, 1989.

    Article  Google Scholar 

  4. Battan R., Mariuz P., Raviglione M.C., Sabatini M.T., Mullen M.P., Poretsky L. Pneumocystis carinii infection of the thyroid in a hypothyroid patient with AIDS: diagnosis by fine needle aspiration biopsy. J. Clin. Endocrinol. Metab. 72: 724, 1991.

    Article  PubMed  CAS  Google Scholar 

  5. Gallant J.E., Enriquez R.E., Cohen K.L., Hammers L.W. Pneumocystis carinii thyroiditis. Am J Med. 84: 303, 1988.

    Article  PubMed  CAS  Google Scholar 

  6. Drucker D.J., Bailey D., Rotstein L. Thyroiditis as the presenting manifestation of disseminated extrapulmonary Pneumocystis carinii infection. J. Clin. Endocrinol. Metab. 71: 1663, 1990.

    Article  PubMed  CAS  Google Scholar 

  7. Volpe R. Acute and subacute thyroiditis. Pharmacol Ther. 1: 171, 1976.

    Google Scholar 

  8. Lopez-Majano V., Sion A., Friedell M.T., Chefec G., Abraira C. Subacute thyroiditis associated with lymphosarcoma of the thyroid. Int. Surg. 60: 172, 1975.

    PubMed  CAS  Google Scholar 

  9. Shimaoka K., Van Herle A.J., Dinogru A. Thyrotoxicosis secondary to involvement of the thyroid with malignant lymphoma. J. Clin. Endocrinol. Metab. 43: 64, 1976.

    Article  PubMed  CAS  Google Scholar 

  10. Rosen I.B., Strawbridge H.G., Walfish P.G., Bain J. Malignant pseudothyroiditis: A new clinical entity. Am. J. Surg. 136: 445, 1978.

    Article  PubMed  CAS  Google Scholar 

  11. Logue J.P., Hale R., Stewart A.L., Duthie M.B., Banerjee S.S. Primary malignant lymphoma of the thyroid: a clinico pathological analysis. Int. J. Rad. Oncol. Biol. Phys. 22: 929, 1992.

    Article  CAS  Google Scholar 

  12. Charles M.D. Thyroid and whole body imaging. In: Ingbar S.H., Braverman L.E. (Eds.), The Thyroid, Fifth ed. J.B. Lippincott Co., Philadelphia, 1986. p. 458.

    Google Scholar 

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Gochu, J., Piper, B., Montana, J. et al. Lymphoma of the thyroid mimicking thyroiditis in a patient with the acquired immune deficiency syndrome. J Endocrinol Invest 17, 279–282 (1994). https://doi.org/10.1007/BF03348976

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  • DOI: https://doi.org/10.1007/BF03348976

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