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Depression in stroke patients with left and right hemisphere lesions. A study in geriatric rehabilitation in-patients

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Abstract

To analyze possible differences in depression rate and symptomatology in stroke patients with left and right hemisphere lesions, ninety- three patients in geriatric rehabilitation wards with a mean age of 76 years were studied. A clinical psychiatric examination was used together with two depression rating scales. Depression prevalence was 46%, and there was no difference between left and right hemisphere lesions. Mean depression scores in the two rating scales showed no significant difference regarding location of lesions. It is concluded that in this elderly, moderately handicapped, stroke population there was no significant difference in depression rate between patients with left and right hemisphere lesions. (Aging Clin. Exp. Res. 6: 49- 56, 1994)

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References

  1. Primeau F.: Post-stroke depression: A critical review of the literature. Can. J. Psychiatr. 33: 757–765, 1988.

    CAS  Google Scholar 

  2. Parikh R.M., Robinson R.G., Lipsey J.R., Starkstein S.E., Fedoroff P., Price T.R.: The impact of post-stroke depression on recovery in activities of daily living over a 2-year follow-up. Arch. Neurol. 47: 785–789, 1990.

    Article  PubMed  CAS  Google Scholar 

  3. Catapano F., Galderisi S.: Depression and cerebral stroke. J. Clin. Psychiatry 51 (Suppl.): 9–12, 1990.

    PubMed  Google Scholar 

  4. House A., Dennis M., Mogridge L., Warlow C., Hawton K., Jones L.: Mood disorders in the year after first stroke. Er. J. Psychiatry 158: 83–92, 1991.

    Article  CAS  Google Scholar 

  5. Sharpe M., Hawton K., House A., Molyneux A., Sandercock P., Bamford J., Warlow C.: Mood disorders in long-term survivors of stroke: associations with brain lesion location and volume. Psychol. Med. 20: 815–828, 1990.

    Article  PubMed  CAS  Google Scholar 

  6. Robinson R.G., Lipsey J.R., Pearlson G.D.: The occurrence and treatment of post-stroke mood disorder. Compr. Ther. 10: 19–24, 1984.

    PubMed  CAS  Google Scholar 

  7. Fedoroff J.P., Robinson R.G.: Tricyclic antidepressants in the treatment of poststroke depression. J. Clin. Psychiatry 50 (Suppl.): 18–23, 1989.

    PubMed  Google Scholar 

  8. Diagnostic and statistical manual of mental disorders, DSM-III-R ed. 3 revised. American Psychiatric Association, Washington, D.C., 1987.

  9. House A., Dennis M., Warlow C., Hawton K., Molyneux A.: Mood disorders after stroke and their relation to lesion location. Brain 113: 1113–1129, 1990.

    Article  PubMed  Google Scholar 

  10. Egelko S., Simon D., Riley E., Gordon W., Ruckdeschel-Hibbard M., Diller L.: First year after stroke: tracking cognitive and affective deficits. Arch. Phys. Med. Rehabil. 70: 297–302, 1989.

    PubMed  CAS  Google Scholar 

  11. Sackeim H.A., Greenberg M.S., Weiman A.L., Gur R.C., Hungerbuhler J.P., Geschwind N.: Hemispheric asymmetry in the expression of positive and negative emotions. Arch. Neurol. 39: 210–218, 1982.

    Article  PubMed  CAS  Google Scholar 

  12. Robinson R.G., Szetela B.: Mood change following left hemisphere brain injury. Ann. Neurol. 9: 447–452, 1981.

    Article  PubMed  CAS  Google Scholar 

  13. Robinson R.G., Price T.R.: Post stroke depression disorders: A follow-up study of 103 patients. Stroke13: 635–641, 1982.

    Article  PubMed  CAS  Google Scholar 

  14. Robinson R.G., Starr L.B., Kubos K.L., Price T.R.: A 2-year longitudinal study of post-stroke mood disorders: Findings during the initial evaluation. Stroke14: 736- 741, 1983.

    Article  PubMed  CAS  Google Scholar 

  15. Robinson R.G., Kubos K.L., Starr L.B., Rao K., Price T.R.: Mood changes in stroke patients: Relationship to lesion location. Comp. Psychiatry24: 555–566, 1983.

    Article  CAS  Google Scholar 

  16. Robinson R.G., Starr L.B., Lipsey J.R., Rao K., Price T.R.: A 2-year longitudinal study of post-stroke mood disorders: Dynamic changes in associated variables over the first six months of follow-up. Stroke15: 510–517, 1984.

    Article  PubMed  CAS  Google Scholar 

  17. Fedoroff J.P., Starkstein S.E., Parikh R.M., Price T.R., Robinson R.G.: Are depressive symptoms nonspecific in patients with acute stroke? Am. J. Psychiatry148: 1172–1176, 1991.

    PubMed  CAS  Google Scholar 

  18. Robinson R.G., Bolduc P.L., Price T.R.: Two-year longitudinal study of poststroke mood disorders: diagnosis and outcome at one and two years. Stroke18: 837–843, 1987.

    Article  PubMed  CAS  Google Scholar 

  19. Robins A.H.: Are stroke patients more depressed than other disabled subjects? J. Chronic Dis. 29: 479–482, 1976.

    Article  PubMed  CAS  Google Scholar 

  20. Feibel J.H., Springer C.J.: Depression and failure to resume activities after stroke. Arch. Phys. Med. Rehabil. 63: 276–278, 1982.

    PubMed  CAS  Google Scholar 

  21. Finkelstein S., Benowitz L.I., Baldessarini R.J., Arana G.W., Levine D., Woo E., Bear D., Moya K., Stoll A.L.: Mood, vegetative disturbance and dexamethasone suppression test after stroke. Ann. Neurol. 12: 463–468, 1982.

    Article  Google Scholar 

  22. Reding M., Orto L., Willensky P., Fortuna I., Day N., Steiner S.F., Gehr L., McDowell F.: The dexamethasone suppression test: An indicator of depression in stroke but not a predictor of rehabilitation outcome. Arch. Neurol. 42: 209–212, 1985.

    Article  PubMed  CAS  Google Scholar 

  23. Sinyor D., Jacques P., Kaloupek D.G., Becker R., Goldenberg M., Coopersmith H.: Post-stroke depression and lesion location: An attempted replication. Brain109: 537–546, 1986.

    Article  PubMed  Google Scholar 

  24. Ebrahim S., Barer D., Nouri F.: Affective illness after stroke. Br. J. Psychiatry151: 52–56, 1987.

    Article  PubMed  CAS  Google Scholar 

  25. Cullum CM., Bigler E.D.: Short form MMPI findings in patients with predominantly lateralized cerebral dysfunction: Neuropsychological and CT-derived parameters. J. Nerv. Ment. Dis. 176: 332–342, 1988.

    Article  PubMed  CAS  Google Scholar 

  26. Eastwood M.R., Rifat S.L., Nobbs H., Ruderman J.: Mood disorder following cerebrovascular accident. Br. J. Psychiatry154: 195–200, 1989.

    Article  PubMed  CAS  Google Scholar 

  27. Malec J.F., Richardson J.W., Sinaki M., O’Brien M.W.: Types of affective response to stroke. Arch. Phys. Med. Rehabil. 71: 279–284, 1990.

    PubMed  CAS  Google Scholar 

  28. Morris P.L.P., Robinson R.G., Raphael B.: Prevalence and course of depressive disorders in hospitalized stroke patients. Int. J. Psychiatry Med. 20: 349–364, 1990.

    Article  PubMed  CAS  Google Scholar 

  29. Cullum CM., Bigler E.D.: Short- and long-term psychological status following stroke. J. Nerv. Ment. Dis. 179: 274–278, 1991.

    Article  PubMed  CAS  Google Scholar 

  30. Stern R.A., Bachman D.L.: Depressive symptoms following stroke. Am. J. Psychiatry148: 351–356, 1991.

    PubMed  CAS  Google Scholar 

  31. Spitzer R.L., Williams J.B., Gibbon M.: Instruction manual for the structured clinical interview for DSM-III-R. Biometric Research Department, New York State Psychiatric Institute, New York, 1986.

    Google Scholar 

  32. Robinson R.G., Chait R.M.: Emotional correlates of structural brain injury with particular emphasis on post-stroke mood disorders. Crit. Rev. Clin. Neurobiol. 1: 285–319, 1985.

    CAS  Google Scholar 

  33. Agrell B., Dehlin O.: Comparison of six depression rating scales in geriatric stroke patients. Stroke20: 1190–1194, 1989.

    Article  PubMed  CAS  Google Scholar 

  34. Montgomery S.A., Åsberg M.: A new depression scale designed to be sensitive to change. Br. J. Psychiatry 134: 382–389, 1979.

    Article  PubMed  CAS  Google Scholar 

  35. Zung W.W.K.: A self-rating depression scale. Arch. Gen. Psychiatry12: 63–70, 1965.

    Article  PubMed  CAS  Google Scholar 

  36. Cronbach L.J.: Coefficient alpha and the internal structure of tests. Psychometrika16: 297–334, 1951.

    Article  Google Scholar 

  37. Folstein M.F., Folstein S.E., Mc Hugh P.R.: “Mini-mental state”. A practical method for grading the cognitive state of patients to the clinician. J. Psychiatr. Res. 12: 189–198, 1975.

    Article  PubMed  CAS  Google Scholar 

  38. Mahoney F.J., Barthel D.W.: Functional evaluation: Barthel Index. Md. State J. 14: 61–65, 1965.

    CAS  Google Scholar 

  39. Wade D.T., Legh-Smith J., Hewer A.: Depressed mood after stroke. Br. J. Psychiatry151: 200–205, 1987.

    Article  PubMed  CAS  Google Scholar 

  40. Bolla-Wilson K., Robinson R.G., Starkstein S.E., Boston J., Price T.R.: Lateralization of dementia of depression in stroke patients. Am. J. Psychiatry146: 627–634, 1989.

    PubMed  CAS  Google Scholar 

  41. Robinson R.G., Morris P.L.P., Fedoroff J.P.: Depression and cerebrovascular disease. J. Clin. Psychiatry51 (Suppl.): 26–31, 1990.

    PubMed  Google Scholar 

  42. Folstein M.F., Maiberger R., McHugh P.R.: Mood disorder as a specific complication of stroke. J. Neurol. Neurosurg. Psychiatry40: 1018–1020, 1977.

    Article  PubMed  CAS  Google Scholar 

  43. Robinson R.G., Kubos K.L., Starr L.B., Rao K., Price T.R.: Mood disorders in stroke patients: importance of location of lesion. Brain107: 81–93, 1984.

    Article  PubMed  Google Scholar 

  44. Dam H., Pedersen E., Ahlgren P.: Depression among patients with stroke. Acta Psychiatr. Scand. 80: 118–124, 1989.

    Article  PubMed  CAS  Google Scholar 

  45. House A., Dennis M., Warlow C., Hawton K., Molyneux A.: The relationship between intellectual impairment and mood disorder in the first year after stroke. Psychol. Med. 20: 805–814, 1990.

    Article  PubMed  CAS  Google Scholar 

  46. Rosse R.B., Ciolino C.P.: Effects of cortical lesion location on psychiatric consultation referral for depressed stroke in-patients. Int. J. Psychiatry Med. 15: 311–320, 1985/86.

    Article  PubMed  Google Scholar 

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  1. Geriatric Clinic, University of Lund, Norra sjukhuset, 22185, Lund, Sweden

    Berit Agrell M.D. & O. Dehlin

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  1. Berit Agrell M.D.
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  2. O. Dehlin
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Agrell, B., Dehlin, O. Depression in stroke patients with left and right hemisphere lesions. A study in geriatric rehabilitation in-patients. Aging Clin Exp Res 6, 49–56 (1994). https://doi.org/10.1007/BF03324213

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  • DOI: https://doi.org/10.1007/BF03324213

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