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Reductive amination of aldehydes with sodium borohydride and lithium aluminum hydride in the presence of lithium perchlorate

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Abstract

A one-pot high yielding reductive amination of aldehydes with primary and secondary amines using LiClO4/NaBH4 and LiClO4/LiAlH4 as reducing agents in diethyl ether is described.

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Authors and Affiliations

  1. Department of Chemistry, Queen’s University, Kingston, Ontario, Canada

    R. Stan Brown

  2. Department of Chemistry, Department of Chemistry, Sharif University of Technology, P.O. Box 11365-9516, Tehran, Iran

    M. R. Saidi & A. Ziyaei-Halimjani

Authors
  1. M. R. Saidi
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  2. R. Stan Brown
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  3. A. Ziyaei-Halimjani
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Correspondence to M. R. Saidi.

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Saidi, M.R., Brown, R.S. & Ziyaei-Halimjani, A. Reductive amination of aldehydes with sodium borohydride and lithium aluminum hydride in the presence of lithium perchlorate. JICS 4, 194–198 (2007). https://doi.org/10.1007/BF03245966

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  • DOI: https://doi.org/10.1007/BF03245966

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