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Synthesis and characterization of iron oxide nanoparticles decorated with carboxymethyl curdlan

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Conclusions

We have synthesized the SPION coated with CMC and investigated the stability in water,T 2 relaxation rate and cytotoxicity. The coating with CMC improved the stability in water and reduced the cytotoxicity to cell viability. Furthermore, the CMC-coated SPION showed superparamagnetic behaviors. The CMC-coated SPION may be used for cellular andin vivo imaging. When CMC are chemically modified for conjugation of specific ligand, the CMCcoated SPION may have a great potential for biomedical applications.

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References

  1. A. K. Gupta and M. Gupta,Biomaterials,26, 3995 (2005). (b) A. S. G. Curits and C. Wilkinson,Trends Biotech.,19, 97 (2001). (c) J. M. Wilkinson,Med. Device Techonol.,14, 29 (2003).

    Article  CAS  Google Scholar 

  2. Y. Zhang, N. Kohler, and M. Zhang,Biomaterials,23, 1553 (2002).

    Article  CAS  Google Scholar 

  3. Y. Y. Liang and L. M. Zhang,Biomacromolecules,8, 1480 (2007). (b) A. Zhu, L. Yuan, and T. Liao,Int. J. Phram.,28, 361 (2008). (c) H. L. Ma, Y. F. Xu, X. R. Qi, Y. Maitani, and T. Nagai,Int. J. Pharm.,354, 217 (2008). (d) N. Kohler, G. E. Fryxell, and M. Zhang,J. Am. Chem. Soc.,126, 7206 (2004). (e) H. Y. Lee, N. H. Lim, J. A. Seo, S. H. Yuk, B. K. Kwak, G. Khang, H. B. Lee, and S. H. Cho,J. Biomed. Mater. Res. Part B: Appl. Biomater.,79, 142 (2006).

    Article  CAS  Google Scholar 

  4. A. K. Gupta and M. Gupta,Biomaterials,26, 1565 (2005).

    Article  CAS  Google Scholar 

  5. H. Ma, X. Qi, Y. Maitani, and T. Nagai,Int. J. Pharm.,333, 177 (2007).

    Article  CAS  Google Scholar 

  6. T. Harada, A. Misaki, and H. Saito,Arch. Biochem. Biophys.,124, 292 (1968). (b) T. Sasaki, N. Abiko, Y. Sugino, and K. Nitta,Cancer Res.,38, 379 (1978). (c) M. Nakata, T. Kawaguchi, Y. Kodama, and A. Konno, Polymer,39, 109 (1997).

    Article  CAS  Google Scholar 

  7. T. Yoshida, K. Hatanaka, and T. Uryu,Macromolecules,23, 3717 (1990). (b) G. Borjihan, G. Y. Baigude, H. Nakashima, and T. Uryu,Polym. Adv. Technol.,24, 326 (2003).

    Article  CAS  Google Scholar 

  8. K. Na, K. H. Park, S. W. Kim, and Y. H. Bae,J. Control. Release,69, 225 (2000).

    Article  CAS  Google Scholar 

  9. H. Lee, E. Lee, D. K. Kim, N. K. Jang, Y. Y. Jeong, and S. Jon,J. Am. Chem. Soc.,128, 7383 (2006).

    Article  CAS  Google Scholar 

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Authors and Affiliations

  1. Department of Nuclear Medicine, Chonbuk National University Medical School, Jeonju, 561-756, Jeonbuk, Korea

    Chang-Moon Lee, Hwan-Jeong Jeong, Eun-Mi Kim, Su-Jin Cheong, Eun-Hye Park, Dong Wook Kim, Seok Tae Lim & Myung-Hee Sohn

  2. Research Institute of Clinical Medicine, Chonbuk National University Medical School, Jeonju, 561-756, Jeonbuk, Korea

    Chang-Moon Lee, Hwan-Jeong Jeong, Eun-Mi Kim, Su-Jin Cheong, Eun-Hye Park, Dong Wook Kim, Seok Tae Lim & Myung-Hee Sohn

  3. Institute for Medical Sciences, Chonbuk National University Medical School, Jeonju, 561-756, Jeonbuk, Korea

    Chang-Moon Lee, Hwan-Jeong Jeong, Eun-Mi Kim, Su-Jin Cheong, Eun-Hye Park, Dong Wook Kim, Seok Tae Lim & Myung-Hee Sohn

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  1. Chang-Moon Lee
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Correspondence to Hwan-Jeong Jeong.

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Lee, CM., Jeong, HJ., Kim, EM. et al. Synthesis and characterization of iron oxide nanoparticles decorated with carboxymethyl curdlan. Macromol. Res. 17, 133–136 (2009). https://doi.org/10.1007/BF03218667

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  • DOI: https://doi.org/10.1007/BF03218667

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