Skip to main content
SpringerLink
Log in

Characterization of poly(ethylene oxide)-b-poly(L-lactide) block copolymer by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry

  • Published:
Macromolecular Research Aims and scope Submit manuscript

Abstract

A poly(ethylene oxide)-b-poly(L-lactide) diblock copolymer (PEO-b-PLLA) is characterized by matrixassisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) and a block length distribution map is constructed. Although the MALDI-TOF mass spectrum of PEO-b-PLLA is very complicated, most of the polymer species were identified by isolating the overlapped isotope patterns and by fitting the overlapped peaks to the Schulz-Zimm distribution function. Reconstructed MALDI-TOF MS spectrum was nearly identical to the measured spectrum and this method shows its potential to be developed as an easy and fast analysis method of low molecular weight block copolymers.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  1. B. Jeong, Y. H. Bae, D. S. Lee, and S. W. Kim,Nature,388, 860 (1997).

    Article  CAS  Google Scholar 

  2. S. Tanodekaew, R. Pannu, F. Heatley, D. Attwood, and C. Booth,Macromol. Chem. Phys.,198, 927 (1997).

    Article  CAS  Google Scholar 

  3. H. T. Lee and D. S. Lee,Macromol. Res.,10, 359 (2002).

    Article  CAS  Google Scholar 

  4. S. H. Lee, S. H. Kim, Y. H. Kim, and Y. -K. Han,Macromol. Res.,10, 85 (2002).

    Article  Google Scholar 

  5. G. Glöckner,Gradient HPLC of Copolymers and Chromatographic Cross-Fractionation, Springer-Verlag, Berlin, 1992.

    Google Scholar 

  6. H. Pasch and B. Trathnigg,HPLC of Polymers, Springer-Verlag, Berlin, 1997.

    Google Scholar 

  7. D. Berek,Prog. Polym. Sci.,25, 873 (2000).

    Article  CAS  Google Scholar 

  8. R. Murphy, M. Schure, and J. Foley,Anal. Chem.,70, 4353 (1998).

    Article  CAS  Google Scholar 

  9. P. Jandera, M. Holcapek, and L. Kolarova,J. Chromatogr. A,869, 65 (2000).

    Article  CAS  Google Scholar 

  10. S. Park, D. Cho, J. Ryu, K. Kwon, W. Lee, and T. Chang,Macromolecules,35, 5974 (2002).

    Article  CAS  Google Scholar 

  11. B. G. Belenkii, E. S. Gankina, M. B. Tennikov, and L. Z. Vilenchik,J. Chromatogr.,147, 99 (1978).

    Article  CAS  Google Scholar 

  12. A. M. Belu, J. M. DeSimone, R. W. Linton, G. W. Lange, and R. M. Friedman,J. Am. Soc. Mass Spectrom.,7, 11 (1996).

    Article  CAS  Google Scholar 

  13. A. T. Jackson, H. T. Yates, J. H. Scrivens, M. R. Green, and R. H. Bateman,J. Am. Soc. Mass Spectrom.,8, 1206 (1997).

    Article  CAS  Google Scholar 

  14. D. C. Schriemer, R. M. Whittal, and L. Li,Macromolecules,30, 1955 (1997).

    Article  CAS  Google Scholar 

  15. M. W. F. Nielen,Mass. Spec. Rev.,18, 309 (1999).

    Article  CAS  Google Scholar 

  16. Y. C. Shin, K. Y. Choi, M. Y. Jin, S. K. Hong, D. Cho, T. Chang, and M. Ree,Korea Polym. J.,9, 100 (2001).

    CAS  Google Scholar 

  17. D. Cho, S. Park, K. Kwon, and T. Chang,Macromolecules,34, 7570 (2001).

    Article  CAS  Google Scholar 

  18. S. Park, D. Cho, J. Ryu, K. Kwon, T. Chang, and J. Park,J. Chromatogr. A,958, 183 (2002).

    Article  CAS  Google Scholar 

  19. M. S. Montaudo, C. Puglisi, F. Samperi, and G. Montaudo,Macromolecules,31, 3839 (1998).

    Article  CAS  Google Scholar 

  20. M. S. Montaudo and G. Montaudo,Macromolecules,32, 7015 (1999).

    Article  CAS  Google Scholar 

  21. H. Lee, W. Lee, T. Chang, S. Choi, D. S. Lee, H. Ji, W. K. Nonidez, and J. W. Mays,Macromolecules,32, 4143 (1999).

    Article  CAS  Google Scholar 

  22. H. Lee, T. Chang, D. S. Lee, M. S. Shim, H. Ji, W. K. Nonidez, and J. W. Mays,Anal. Chem.,73, 1726 (2001).

    Article  CAS  Google Scholar 

  23. D. Cho, S. Park, T. Chang, K. Ute, I. Fukuda, and T. Kitayama,Anal. Chem.,74, 1928 (2002).

    Article  CAS  Google Scholar 

  24. D. Cho, J. Hong, S. Park, and T. Chang,J. Chromatogr. A,986, 199 (2003).

    Article  CAS  Google Scholar 

  25. G. Wilczek-Vera, P. O. Danis, and A. Eisenberg,Macromolecules,29, 4036 (1996).

    Article  CAS  Google Scholar 

  26. G. Wilczek-Vera, Y. Yu, K. Waddell, P. O. Danis, and A. Eisenberg,Rapid Commun. Mass Spectrom.,13, 764 (1999).

    Article  CAS  Google Scholar 

  27. G. J. van Rooij, M. C. Duursma, C. G. de Koster, R. M. A. Heeren, J. J. Boon, P. J. W. Schuyl, and E. R. E. van der Hage,Anal. Chem.,70, 843 (1998).

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Chemistry and Center for Integrated Molecular Systems, Pohang University of Science and Technology, 790-784, Pohang, Korea

    Jeongmin Hong, Donghyun Cho & Taihyun Chang

  2. Department of Polymer Science and Engineering, Sungkyunkwan University, 440-746, Suwon, Korea

    Woo Sun Shim & Doo Sung Lee

Authors
  1. Jeongmin Hong
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Donghyun Cho
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Taihyun Chang
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Woo Sun Shim
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Doo Sung Lee
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Hong, J., Cho, D., Chang, T. et al. Characterization of poly(ethylene oxide)-b-poly(L-lactide) block copolymer by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. Macromol. Res. 11, 341–346 (2003). https://doi.org/10.1007/BF03218374

Download citation

  • Received:

  • Revised:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF03218374

Keywords

Search

Navigation