Skip to main content
Log in

Indolyl alkaloid derivatives,N b-acetyltryptamine and oxaline from a marine-derived fungus

  • Research Articles
  • Articles
  • Published:
Archives of Pharmacal Research Aims and scope Submit manuscript

Abstract

Indolyl alkaloids,N b-acetyltryptamine (1) and the known oxaline (2) have been isolated from the organic extract of the broth of an unidentified fungus collected from the surface of the marine red algaGracilaria verrucosa. The structure ofN b-acetyltryptamine (1) was assigned on the basis of comprehensive spectroscopic analyses.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  • Buckingham, J., Macdonald, F. M., and Bradley, H. M. (Eds.).Dictionary of Natural Products, Vol. 10, Chapman & Hall, London, pp. 5932–5933, (1994).

    Google Scholar 

  • Faulkner, D. J., Marine natural products.Nat. Prod. Rep., 19, 1–48 (2002).

    CAS  PubMed  Google Scholar 

  • Fish, M. S., Johnson, N. M., and Horning, E. C., Piptadenia alkaloids. Indole bases ofP. peregrina (L.) Benth. and related species.J. Am. Chem. Soc., 77, 5892 (1955).

    Article  CAS  Google Scholar 

  • Morales-Rios, M. S., Espineira, J., and Joseph-Nathan, P.,13C NMR spectroscopy of indole derivatives.Magn. Resonance Chem., 25, 377–395 (1987).

    Article  CAS  Google Scholar 

  • Nagel, D. W., Pachler, K. G. R., Steyn, P. S., Vleggaar, R., and Wessels, P. L., The chemistry and13C NMR assignments of oxaline, a novel alkaloid fromPenicillium oxalicum.Tetrahedron, 32, 2625–2631 (1976).

    Article  CAS  Google Scholar 

  • Pietra, F., Secondary metabolites from marine microorganisms: bacteria, protozoa, algae and fungi. Achievements and prospects.Nat. Prod. Rep., 14, 453–464 (1997).

    Article  CAS  PubMed  Google Scholar 

  • Salmoun, M., Devijver, C., Daloze, D., Braekman, J. C., and van Soest, R. W. M., 5-Hydroxytryptamine-derived alkaloids from two marine sponges of the genusHyrtios.J. Nat. Prod., 65, 1173–1176 (2002).

    Article  CAS  PubMed  Google Scholar 

  • Saxton, J. E., The simple bases, In Manske, R. H. F. (Ed.).The alkaloids, Chemistry and Physiology, Vol. VIII, Academic Press, New York, pp. 8–10, (1965) and references therein.

    Google Scholar 

  • Son, B. W., Choi, J. S., Kim, J. C., Nam, K. W., Kim, D. S., Chung, H. Y., Kang, J. S., and Choi, H. D., Parasitenone, a new epoxycyclohexenone related to gabosine from the marine-derived fungusAspergillus parasiticus.J. Nat. Prod., 65, 794–795 (2002).

    Article  CAS  PubMed  Google Scholar 

  • Yang, S. W. and Cordell, G. A., Metabolism studies of indole derivatives using a staurosporine producer,Streptomyces staurosporeus.J. Nat. Prod., 60, 44–48 (1997).

    Article  CAS  PubMed  Google Scholar 

  • Yang, S. W. and Cordell, G. A., Further metabolic studies of indole and sugar derivatives using the staurosporine producerStreptomyces staurosporeus.J. Nat. Prod., 60, 230–235 (1997).

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Byeng Wha Son.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Li, Y., Li, X.F., Kim, D.S. et al. Indolyl alkaloid derivatives,N b-acetyltryptamine and oxaline from a marine-derived fungus. Arch Pharm Res 26, 21–23 (2003). https://doi.org/10.1007/BF03179925

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF03179925

Key words

Navigation