Skip to main content
Log in

Eperythrozoon infection identified in an unknown aetiology anaemia patient

  • Methods
  • Short Communication
  • Published:
Annals of Microbiology Aims and scope Submit manuscript

Abstract

In this report,Eperythrozoon leading haemolysis was identified in human blood. A patient with long-term anaemia was selected for blood smear examination and electron microscopy. The microscopic results showed a lot of small organisms attaching on the surface of erythrocytes. The partial 16S rRNA gene was amplified and confirmed as haemoplasma by sequence alignment. Phylogenetic analysis showed it fell in the same cluster with otherEperythrozoon species in haemoplasma group. It was the first time to confirm the haemoplasma infection in human blood by molecular assay combined with microscope. Such infection may be a potential criminal of some cases of human unknown origin anaemia.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

References

  • Berent L.M., Messick J.B., Cooper S.K., Cusick P.K. (2000). Specificin situ hybridization ofHaemobartonella felis with a DNA probe and tyramide signal amplification. Vet. Pathol., 37: 47–53.

    Article  CAS  PubMed  Google Scholar 

  • Bidwell D.E., Voller A. (1967). The effect ofEperythrozoon coccoides on infections in mice. Parasitology, 57: 22.

    Google Scholar 

  • Buttner M., Plank G., Heinritzi K. (1995). Effect of immunosuppressive treatment onEperythrozoon suis infection and procine peripheral-blood natural-killer-(NK) cell activity. Zentralb. Veterinarmed. Riehe B, 42: 301–310.

    CAS  Google Scholar 

  • Donovan E.F., Loeb W.F. (1960). Hemobartonellosis in the dog. Vet. Med., 55: 57–62.

    Google Scholar 

  • Elko E.E., Cantrell W. (1968). Phagocytosis and anemia in rats infected withHaemobartonella muris J. Infect. Dis., 118: 324–332.

    CAS  PubMed  Google Scholar 

  • Heinritzi K., Plank G. (1992). The effect ofEperythrozoon suis infection on the osmotic fragility of erythrocytes. Berl. Munch. Tierarztl. Wochenschr., 105: 380–383.

    CAS  PubMed  Google Scholar 

  • Henry S.C. (1979). Clinical observations of eperythrozoonosis. J. Am. Vet. Med. Assoc., 174: 601–603.

    CAS  PubMed  Google Scholar 

  • Messick J.B. (2004). Hemotrophicmycoplasmas (hemoplasmas): a review and new insights into pathogenic potentia. Vet. Clin. Pathol., 33: 2–13.

    Article  PubMed  Google Scholar 

  • Neimark H., Johansson K.E., Rikihisa Y., Tully J.G. (2001). Proposal to transfer some members of the generaHaemobartonella andEperythrozoon to the genusMycoplasma with descriptions of ‘Candidatus Mycoplasma haemofelis’, ‘Candidatus Mycoplasma haemomuris’, ‘Candidatus Mycoplasma haemosuis’ and ‘Candidatus Mycoplasma wenyonii’. Int. J. Syst. Evol. Microbiol., 51: 891–899.

    CAS  PubMed  Google Scholar 

  • Neimark H., Hoff B., Ganter M. (2004).Mycoplasma ovis comb. nov. (formerlyEperythrozoon ovis), an epierythrocytic of haemolytic anemia in sheep and goats. Int. J. Syst. Evol. Microbiol., 54: 365–361.

    Article  CAS  PubMed  Google Scholar 

  • Ristic M., Kreier J.P. (1984). Family II. Bartonellaceae. In: Krieg N.R., Holt J.G., Eds, Bergey’s Manual of Systematic Bacteriology, Vol. 1 The Williams & Wilkins Co., Baltimore, Md, pp. 717–719.

    Google Scholar 

  • Sheriff D., Clapp K.H., Reid M.A. (1966).Eperythrozoon ovis infection in South Australia. Aust. Vet. J., 42: 169–176.

    Article  CAS  PubMed  Google Scholar 

  • Stoffregen W.C., Alt D.P., Palmer M.V., Olsen S.C. (2006). Identification of a haemomycoplasma species in anemic reindeer (rangifer tarandus). J. Wildlife. Dis., 42: 249–258.

    CAS  Google Scholar 

  • Sutton R.H., Charleston W.A., Collins G.H. (1977).Eperythrozoon wenyoni — a blood parasite of cattle. A first report in New Zealand. N. Z. Vet. J., 25: 8–9.

    CAS  PubMed  Google Scholar 

  • Yang D., Tai X., Qiu Y., Yun S. (2000). Prevalence ofEperythrozoon spp. infection and congenital eperythrozoonosis in humans in Inner Mongolia, China. Epidemiol. Infect., 125: 421–426.

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Xiuguo Hua.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Yuan, C., Liang, A., Yu, F. et al. Eperythrozoon infection identified in an unknown aetiology anaemia patient. Ann. Microbiol. 57, 467–469 (2007). https://doi.org/10.1007/BF03175091

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF03175091

Key words

Navigation