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Recent considerations in recurrent cellulitis

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Abstract

Cellulitis is a frequently diagnosed syndrome that causes considerable morbidity. For a subset of patients, recurrent bouts of infection impact their quality of life. Most cases are due to b-hemolytic streptococci or Staphylococcus aureus. Inclusion of interdigital space (toe web) or mucosal (anal) swab cultures may increase the ability to define pathogens among patients with lower extremity cellulitis. The pathogenesis of cellulitis is complex, and more work is needed so that novel therapies and vaccines can be developed to improve treatment and prevention of this disorder.

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References and Recommended Reading

  1. Parada JP, Maslow JN, Clinical syndromes associated with adult pneumococcal cellulitis. Scand J Infect Dis 2000, 32:133–136.

    Article  PubMed  CAS  Google Scholar 

  2. Baddour LM, Cellulitis syndromes: an update. Int J Antimicrob Agents 2000, 14:113–116.

    Article  PubMed  CAS  Google Scholar 

  3. Baddour LM, Bisno AL, Recurrent cellulitis after saphenous venectomy for coronary bypass surgery. Ann Intern Med 1982, 97:493–496.

    PubMed  CAS  Google Scholar 

  4. Mertz KR, Baddour LM, Bell JB, Breast cellulitis following breast conservation therapy: a novel complication of medical progress. Clin Infect Dis 1998, 26:481–486.

    Article  PubMed  CAS  Google Scholar 

  5. Dupuy A, Benchikhi H, Roujeau JC, et al. Risk factors for erysipelas of the leg (cellulitis): case-control study. BMJ 1999, 318:1591–1594. This is the first case-control study that examines risk factors for the development of lower extremity cellulitis.

    PubMed  CAS  Google Scholar 

  6. Baddour LM, Breast cellulitis complicating breast conservation therapy. J Intern Med 1999, 245:5–9.

    Article  PubMed  CAS  Google Scholar 

  7. Brewer VH, Hahn KA, Rohrbach BW, et al. Risk factor analysis for breast cellulitis complicating breast conservation therapy. Clin Infect Dis 2000, 31:654–659. This is the first case-control study that examines risk factors for the development of breast cellulitis.

    Article  PubMed  CAS  Google Scholar 

  8. Rockson SG, Lymphedema. Am J Med 2001, 110:288–295. This work is an excellent review of lymphedema and its complications, including cellulitis.

    Article  Google Scholar 

  9. Mellon E, Powell S, Mortimer P, Ryan TJ, Evidence for altered cell-mediated immunity in postmastectomy lymphedema. Br J Dermatol 1997, 137:928–933.

    Article  Google Scholar 

  10. de Godoy JMP, de Godoy MF, Valente A, et al. Lymphoscintigraphic evaluation in patients after erysipelas. Lymphol 2000, 33:177–180.

    Google Scholar 

  11. Binswanger IA, Kral AH, Bluthenthal RN, et al. High prevalence of abscesses and cellulitis among community-recruited injection drug users in San Francisco. Clin Infect Dis 2000, 30:579–581.

    Article  PubMed  CAS  Google Scholar 

  12. Baddour LM, Googe PB, Stevens SL, Biopsy specimen findings in patients with previous lower extremity cellulitis after saphenous venectomy for coronary artery bypass graft surgery. J Am Acad Dermatol 1997, 37:246–249.

    Article  PubMed  CAS  Google Scholar 

  13. Baddour LM, Googe PB, Prince TL, Possible role of cellular immunity: a case of cellulitis. Clin Infect Dis 2001, 32:e17-e21.

    Article  Google Scholar 

  14. Sadow KB, Chamberlain JM, Blood cultures in the evaluation of children with cellulitis. Pediatrics 1998, 101:1–4.

    Article  Google Scholar 

  15. Perl B, Gottehrer NP, Raveh D, et al. Cost-effectiveness of blood cultures for adult patients with cellulitis. Clin Infect Dis 1999, 29:1483–1488.

    Article  PubMed  CAS  Google Scholar 

  16. Woo PCY, Lum PNL, Wong SSY, et al. Cellulitis complicating lymphoedema. Eur J Clin Microbiol Infect Dis 2000, 19:294–297. This investigation suggests that cellulitis in the setting of lymphedema may be clinically distinct from that in patients without cellulitis.

    Article  PubMed  CAS  Google Scholar 

  17. Baddour LM, Bisno AL, Non-group a beta-hemolytic streptococcus cellulitis. Association with venous and lymphatic compromise. Am J Med 1985, 79:155–159.

    Article  PubMed  CAS  Google Scholar 

  18. Semel JD, Goldin H, Association of athlete’s foot with cellulitis of the lower extremities: diagnostic value of bacterial cultures of ipsilateral space samples. Clin Infect Dis 1996, 23:1162–1164.

    PubMed  CAS  Google Scholar 

  19. Eriksson BKG, Anal colonization of group G ß-hemolytic streptococci in relapsing erysipelas of the lower extremity. Clin Infect Dis 1999, 29:1319–1320.

    Article  PubMed  CAS  Google Scholar 

  20. Szuba A, Cooke JP, Yousuf S, Rockson SG, Decongestive lymphatic therapy for patients with cancer-related or primary lymphedema. Am J Med 2000, 109:296–300.

    Article  PubMed  CAS  Google Scholar 

  21. Miller TA, Wyatt LE, Rudkin GH, Staged skin and subcutaneous excision for lymphedema:a favorable report of long-term results. Plast Reconstr Surg 1998, 102:1486–1497.

    Article  PubMed  CAS  Google Scholar 

  22. Schwartz GR, Wright SW, Changing bacteriology of periorbital cellulitis. Ann Emerg Med 1996, 28:617–620.

    Article  PubMed  CAS  Google Scholar 

  23. Balaban N, Goldkorn T, Nhan RT, et al. Autoinducer of virulence as a target for vaccine and therapy against Staphylococcus aureus. Science 1998, 280:438–440. This investigation demonstrated that prevention of cellulitis with a vaccine was achievable in a murine model of infection.

    Article  PubMed  CAS  Google Scholar 

  24. Bisno AL, Gaviria JM, Murine model of recurrent group G streptococcal cellulitis: no evidence of protective immunity. Infect Immun 1997, 65:4926–4930.

    PubMed  CAS  Google Scholar 

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  1. University of Tennessee Medical Center at Knoxville, 1924 Alcoa Highway U-114, 38920, Knoxville, TN, USA

    Larry M. Baddour MD

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  1. Larry M. Baddour MD
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Baddour, L.M. Recent considerations in recurrent cellulitis. Curr Infect Dis Rep 3, 461–465 (2001). https://doi.org/10.1007/BF03160471

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  • DOI: https://doi.org/10.1007/BF03160471

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