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Changes of neuron-specific enolase concentration in plasma after cardiac arrest and resuscitation

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Molecular and Chemical Neuropathology

Abstract

The concentration of neuron-specific enolase (NSE) was measured in plasma of 18 patients after cardiac arrest and resuscitation (14 nonsurvivors and 4 survivors). In all patients, the NSE concentration was significantly higher in comparison to reference values. The highest concentration was measured in nonsurvivors. Time-course investigation in the first 24 h after cardiac arrest was performed in five patients. Two nonsurvivors and one survivor of the five patients showed a significant rise, and a NSE peak concentration of 42.7 μg/L, 13.6 μg/L, and 10.5 μg/L, respectively, was found 10–19 h after cardiac arrest.

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Dauberschmidt, R., Zinsmeyer, J., Mrochen, H. et al. Changes of neuron-specific enolase concentration in plasma after cardiac arrest and resuscitation. Molecular and Chemical Neuropathology 14, 237–245 (1991). https://doi.org/10.1007/BF03159939

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  • DOI: https://doi.org/10.1007/BF03159939

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