Abstract
A 61-year-old male with a history of metastatic colorectal cancer was referred to our hospital for primary coronary intervention because of acute ST-elevation myocardial infarction. Coronary angiography, however, revealed no significant stenoses. When asked, the patient revealed that capecitabine (Xeloda®) was started by his oncologist one day before admission. It is known that this oral 5-FU analogue drug, used in metastatic colorectal cancer, can cause coronary artery spasms. The main treatment of capecitabine-induced vasospasm is discontinuation of the drug. Indeed, after cessation of the drug the patient remained free of symptoms and the ECG abnormalities normalised. (Neth Heart J 2009;17:288–91.)
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Departments of Cardiology, Rijnstate Hospital Arnhem and Radboud University Nijmegen Medical Centre, the Netherlands
Department of Cardiology, Interventional Cardiology Section, Rijnstate Hospital, Arnhem, the Netherlands
C. Camaro Department of Cardiology, Interventional Cardiology Section, Rijnstate Hospital, PO Box 9555, 6800 TA Arnhem, the Netherlands and Department of Cardiology, Radboud University Nijmegen, Medical Centre, PO Box 9101, 6500 HB Nijmegen, the Netherlands
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Camaro, C., Danse, P.W. & Bosker, H.A. Acute chest pain in a patient treated with capecitabine. NHJL 17, 288–291 (2009). https://doi.org/10.1007/BF03086268
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DOI: https://doi.org/10.1007/BF03086268